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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Development of Corrosion Resistant Prestressed Concrete Strands Utilizing Liquie Plasma Technology

    SBC: CAP Technologies LLC            Topic: 141FH6

    This proposal is to prove the feasibility of a new and novel zinc-based alloyed coating on both the manufactured Grade 270 0.5 and 0.6 low-relaxation strands and for the individual wires used to make the 7-wire strand for prestressed concrete used in bridge construction. The application of the coating will use CAP Technologies LLC [CAP] proprietary and patented foam plasma technology also kn ...

    SBIR Phase I 2014 Department of Transportation
  2. Enhancing Rural Access to Capital Through Development of a Local Crowdfunding Incubator

    SBC: LOCAL CROWD, LLC, THE            Topic: 86

    Strong rural economies need strong entrepreneurs who can start businesses and create jobs. The RUPRI Center for Rural Entrepreneurship reports that regions with high levels of entrepreneurship have 73% higher employment growth, 14% higher wage growth, 87% higher birth rate of new firms, and 45% higher productivity growth--all indicators of robust and sustainable local economies. Entrepreneurs are ...

    SBIR Phase I 2014 Department of Agriculture
  3. Low-Cost, High Efficiency Integration of Solid-State Lighting and Building Controls Using a Packet Energy Transfer (PET) Power Distribution System

    SBC: VoltServer            Topic: 03a

    Solid state lighting has not yet taken off in commercial buildings due to its high relative installed cost. On a normalized basis, solid state lighting replacement lamps are on the order of two times more expensive than equivalent compact fluorescent lamps (CFLs), and five times more expensive than an equivalent downlight fixture. An additional barrier relates to the performance and cost of the dr ...

    SBIR Phase I 2014 Department of Energy
  4. Glycoengineered baculoviruses for the production of more efficacious influenza va

    SBC: Glycobac, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): Vaccination significantly reduces morbidity and mortality caused by annual influenza epidemics. Traditionally, influenza vaccines have been manufactured using adapted influenza virus grown in eggs. However, this methodsuffers from inherent disadvantages such as slow production and allergenic egg proteins in the final product. To avoid these drawbacks, new vacci ...

    SBIR Phase I 2014 Department of Health and Human Services
  5. Peptide inhibitors of coronavirus entry

    SBC: Autoimmune Technologies, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): The broad long-term objectives of the proposed work are to develop effective medical countermeasures to be used for the treatment of viral infectious disease caused by exposure to human coronaviruses. The work will focus on the discovery and development of peptide-based therapeutics for the treatment of persons infected with the newly identified Middle Eastern ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. Calcaftor, a CFTR stabilizer for Cystic Fibrosis treatment

    SBC: Calista Therapeutics, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

    SBIR Phase I 2014 Department of Health and Human Services
  7. On Site Mercury Remediation via Activated Fly Ash

    SBC: POLLUTION CONTROL TECHNOLOGIES, LLC            Topic: NIEHS

    DESCRIPTION (provided by applicant): Coal-fired power plants and burners are vital drivers of the U.S. economy-but they unfortunately produce substantial amounts of mercury (Hg) that are seriously harmful to human health, particularly linked to damages ofthe nervous system. Healthcare costs due to Hg exposure are estimated to be in the billions of dollars annually. New mercury-emission regulations ...

    SBIR Phase I 2014 Department of Health and Human Services
  8. Engineering cells for concurrent protein drug biosynthesis and polysialylation

    SBC: Glycobac, LLC            Topic: NIGMS

    Project Summary / Abstract Therapeutic proteins, or biologics, represent a 100 billion market that includes drugs such as antibodies, hormones, and many others. The clinical efficacy of biologics is critically determined by their circulating half-lives.Hence, various methods have been developed to increase their circulating half-lives by reducing clearance rates. This is commonly achieved by che ...

    SBIR Phase I 2014 Department of Health and Human Services
  9. Inter-alpha-inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, LLC            Topic: NINDS

    DESCRIPTION (provided by applicant): Neonatal hypoxia-ischemia (HI) remains a major cause of acute perinatal brain injury, leading ultimately to neurologic dysfunction manifesting as cerebral palsy, mental retardation, and epilepsy. Cerebral oxygen deprivation and/or reduced blood flow due to umbilical cord occlusion, prolonged labor, and/or intracranial hemorrhage produce an inflammatory respons ...

    SBIR Phase I 2014 Department of Health and Human Services
  10. Novel coatings releasing synergistic polyphenols promote vascular healing

    SBC: REQUISITE BIOMEDICAL, LLC            Topic: NHLBI

    PROJECT SUMMARY Cardiovascular disease (CVD) remains the number one cause of death in the U.S. Left untreated, CVD can result in the occlusion of key arteries that can precipitate a major cardiac event. Clinicians routinely correct arterial blockages mechanically using a balloon expansion of the lesioned area and placement of a metallic stent to help keep the arteries open. However, the overstretc ...

    STTR Phase I 2014 Department of Health and Human Services

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