Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A Novel Substrate to Amplify Growth Factor Impact on hPSC Differentiation

    SBC: PRIMORIGEN BIOSCIENCES INC.            Topic: 300

    DESCRIPTION provided by applicant Primorigen Biosciences R Project Abstract Primorigen will use SBIR funds to develop a paradigm changing technology for expansion and directed differentiation of human pluripotent stem cells hPSCs using a novel peptide that dramatically reduces costs by amplifying the impact of endogenous growth factors and minimizing the need for exogenous growth factors Th ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Toxoid adjuvant CRM197 production in a stable reduced genome E. coli strain

    SBC: SCARAB GENOMICS, LLC            Topic: NIAID

    DESCRIPTION provided by applicant CRM is an inactive form of diphtheria toxin that when conjugated to a vaccine antigen enhances immunity to generate long lasting vaccination against the antigen Conjugate vaccines containing CRM are common and there are currently seven CRM containing conjugate vaccines on the market The top selling vaccine the CRM containing conjugate vaccine P ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Development of a novel highly effective influenza vaccine

    SBC: Flugen, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Seasonal influenza flu virus an NIAID category C priority pathogen causes widespread infection resulting in at least million cases of severe illness and deaths worldwide Young children and elderly or immunocompromised individuals are typically at greater risk of severe illness or death from influenza Newly emerging strains can result ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Continuous Chromatography Device to Economically Purify Clinical-grade Antibodies

    SBC: Semba Biosciences Inc            Topic: 102

    DESCRIPTION provided by applicant Monoclonal antibodies mAbs have become the leading drug class for cancer treatment and over anti neoplastic mAbs are in the biopharmaceutical pipeline Most mAb therapies must be administered in doses of mg kg resulting in per patient costs of up to $ per year The high price of mAb therapy causes a significant financial burden for patients ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Antibacterial molecular coatings pre-fabricated for biologic wound dressings

    SBC: IMBED BIOSCIENCES, INC            Topic: NIAMS

    DESCRIPTION provided by applicant Clinical infections in burn trauma and surgical wounds represent a huge economic and health care burden In the U S there is a infection rate in surgical wounds and up to a rate in burn wounds The current standard of care is intensive and expensive involving frequent topical application of antimicrobials twice daily with painful dressing changes ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Electrode Arrays for Bloodless Liver Resection and Tumor Ablation

    SBC: MEDICAL ENGINEERING INNOVATIONS, LLC            Topic: 102

    DESCRIPTION provided by applicant Both primary and metastatic liver cancer is common in the US and worldwide The standard treatment for liver cancer is liver resection where part of the liver containing the tumor is surgically removed This operation is associated with considerable blood loss typically between L Blood loss is adversely associated with patient morbidity and survival ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Integrated, self-actuated, blood collection and biomarker purification device

    SBC: Tasso, Inc            Topic: SB122003

    Blood-based point-of-care (POC) diagnostics or remote diagnostics that require specialized equipment only available in centralized, commercial laboratories are currently limited by major logistical and technical barriers. Blood collection can be a traumatic, inconvenient, and inconsistent process that is based on decades-old technologies, such as the lancet-puncture, that are not amenable to new P ...

    SBIR Phase II 2014 Department of DefenseDefense Advanced Research Projects Agency
  8. MASS PRODUCTION OF PERSONALIZED HUMAN ENGINEERED HEART TISSUES

    SBC: Invivosciences, Inc.            Topic: 200

    DESCRIPTION provided by applicant Cardiomyopathy has various forms including hypertrophic cardiomyopathy HCM in prevalence could cause sudden cardiac death in athletes Dilated Cardiomyopathy DCM in prevalence results in an enlarge left ventricle Arrhythmogenic Right Ventricular Dysplasia Cardiomyopathy ARVD C in prevalence causes cardiac fibrosis Yearly over $ ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Development of an In Situ Thermal Extraction Detection System (TEDS) for Rapid, Accurate, Quantitative Analysis of Environmental Pollutants in the Subsurface

    SBC: Ion Signature Technology, Inc.            Topic: TopicH

    The U.S. Environmental Protection Agency (EPA) in its publication Technology News and Trends in 2009 featured the Navy's work that saved 6 years and $3 million delineating chlorinated solvent plumes in soil and groundwater. The Navy used EPA's TRIAD process, which incorporates systematic planning, field analytics, and dynamic work strategies, during its hazardous waste site investigation. A direct ...

    SBIR Phase II 2010 Environmental Protection Agency
  10. Development of an in situ Thermal Extraction Detection System (TEDS) for Rapid, Accurate, Quantitative Analysis of Environmental Pollutants in the Subsurface

    SBC: Ion Signature Technology, Inc.            Topic: 09NCERP1

    The U.S. Environmental Protection Agency (EPA) in its publication Technology News and Trends in 2009 featured the Navy's work that saved 6 years and $3 million delineating chlorinated solvent plumes in soil and groundwater. The Navy used EPA's TRIAD process, which incorporates systematic planning, field analytics, and dynamic work strategies, during its hazardous waste site investigation. A direct ...

    SBIR Phase II 2010 Environmental Protection Agency
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