Award Data

Blood-based point-of-care (POC) diagnostics or remote diagnostics that require specialized equipment only available in centralized, commercial laboratories are currently limited by major logistical and technical barriers. Blood collection can be a traumatic, inconvenient, and inconsistent process that is based on decades-old technologies, such as the lancet-puncture, that are not amenable to new P ...

We propose to design and implement a query-based approach to interoperable modeling and simulation of composite material structures, that usually contain the manufacturing recipe within their design. In Phase I, we established the feasibility of the approach using a demonstration scenario of CAD/CAE interoperability for assemblies. In Phase II, we propose to develop a series of use-case scenarios ...

Blood-based assays require upstream mechanisms to acquire sample from a patient, extract the analyte of interest, and preserve the analyte until it can be quantified. Current point-of-care assays overwhelmingly rely on lancet puncture, which is inconvenient because of the presence of blood that is open to the environment and induces high levels of user error inherent with the multiple steps requir ...

In order to maintain our nation’s technological superiority on air, sea and land, we must respond quicker to emerging threats and reduce the cost of major sensing platforms. Every DoD platform developed nowadays contains at least one sensor, whether it be RF, EO/IR, or acoustic. In fact, in a lot of recent developments, the platform is built around the sensor and exists only to support the senso ...

Current research tools to understand tumor cell migration and metastases are limited to linear gradients or constant flow across cells skewing results. Researchers at the National Institute of Standards and Technology developed a tool called the microfluidic palette which exposes cells to chemical stimuli in a static environment overcoming the limitations above. Several improvements are necessary ...

Optimization of generator performance and maximization of output power are difficult to attain in the generation of hydro-power. This is due to the changing water conditions and corresponding changes in the form of available energy. ESL proposes to use self-tuning controls in combination with a suitably chosen and optimized generator driven by hydro-energy and condition it for distribution to then ...

This program proposes to demonstrate an ultra-low power design methodology and circuits for digital logic employing advanced dynamic voltage scaling (DVS) for asynchronous NULL Convention Logic (NCL) circuits operating in sub-threshold to super-threshold voltage regimes. The power supply voltages of logic block partitions will be independently set by on-chip voltage controllers based on the data p ...

nPoint proposes to design and construct a closed-loop 2mm range-of-motion, 2-axis nano-positioning system with unprecedented precision and resolution. There is considerable need for such a tool in near-future nanomanufacturing, characterization, and lithography. One example is scanned-probe tip-based nanomanufacturing. As such manufacturing comes to commercial fruition, accurate long-range positi ...

ORBITEC proposes to develop functionally graded metallic lattice components for use in advanced rocket propulsion systems. The FGMLC material will utilize an internal intertwined lattice structure to join different constituents of the composite material. This lattice structure will allow a designed gradation from one material to another while maintaining each materials properties. The FGMLC will u ...

The U.S. Environmental Protection Agency (EPA) in its publication Technology News and Trends in 2009 featured the Navy's work that saved 6 years and $3 million delineating chlorinated solvent plumes in soil and groundwater. The Navy used EPA's TRIAD process, which incorporates systematic planning, field analytics, and dynamic work strategies, during its hazardous waste site investigation. A direct ...