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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Molecular Diagnostic to Determine the Sex of Sturgeon at an Early Age

    SBC: APPLIED FOOD TECHNOLOGIES, INC            Topic: 87

    Sturgeons have very high potential to become an important and profitable aquaculture species in the US, as males are grown for meat and brood stock and female sturgeon are primarily raised for their eggs (caviar). In fact, sturgeon caviar is the highest-valued aquaculture product worldwide, selling for $104 - $250 per 50 grams (depending on the quality). One 60 kg adult female can produce approxim ...

    SBIR Phase I 2014 Department of Agriculture
  2. iPAD App for Improving Embryo Transfer Practices

    SBC: ARCHIE MD INC.            Topic: N/A

    This proposal will use interactive mobile technology decision aids for in vitro fertilization (IVF) patients. Phase I will focus on education patients on appropriate embryo transfer numbers. The advent of assisted reproductive technology methods has increased the incidences of high-order multiple births, which are a leading cause of long-term child morbidity, gestational hypertension, placenta p ...

    SBIR Phase I 2014 Department of Health and Human Services
  3. Development of Pills or Tables to Expedite Water Fluoridation

    SBC: KC Industries, LLC            Topic: N/A

    The development & commercialization of an innovative, simple-to-use, durable & cost-effective system capable of delivering fluoride to small & med-size potable water systems is essential to increase the availability of fluoridated water to 80 percent of the nation's population by 2020 (CDC's Health People goal). To achieve this goal, a research & development Plan has been created using sodium flu ...

    SBIR Phase I 2014 Department of Health and Human Services
  4. Innovative Nucleic Acids to Diagnose Endemic Fungal Infections


    Firebird will deliver multiplexed assays that inexpensively detect and distinguish coccidioidomycosis, blastomycosis, and histoplasmosis by targeting the genomic DNA of their causative agents. This assay uses six Firebird technologies: 1. Artificially expanded genetic information systems (AEGIS), which support ultra-clean DNA amplification with ultra-low noise despite the complexity of realbiolog ...

    SBIR Phase I 2014 Department of Health and Human Services
  5. Prostate Cancer Detection Through Urine Headspace Analysis Using Colorimetric Sen


    DESCRIPTION (provided by applicant): In the U.S., prostate cancer is the second leading cause of cancer death in men, and one in six men will eventually develop prostate cancer during his lifetime. Currently, the prostate specific antigen test and digitalrectal examination are the most predominant used tools for prostate cancer detection, but both methods have low specificity and poorly predict t ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. Intravesical Chitosan IL-12 Therapy in an Orthotopic Mouse Bladder Cancer Model

    SBC: SCION CARDIO-VASCULAR, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): This SBIR project brings together the skills and resources of laboratories at Scion Cardio-Vascular Inc. (Scion C-V), Loma Linda University, and North Carolina State University to advance a new signaling molecule treatment for superficial bladder cancer. This treatment delivers the cytokine Interleukin 12 (IL-12) to the bladder wall using Scion C-V's muco ...

    SBIR Phase I 2014 Department of Health and Human Services
  7. Novel selective alpha4beta2 nicotinic receptor antagonists for smoking cessation


    DESCRIPTION (provided by applicant): Smoking remains the number one avoidable cause of death in the United States. Current therapies including nicotine replacement, inhibition of the dopamine system with bupropion, and partial activation of the 4 2 neuronal nicotinic acetylcholine receptor (nAChR) with varenicline have not been particularly effective, with relapse rates at nearly 80% regardless of ...

    SBIR Phase I 2014 Department of Health and Human Services
  8. Calcaftor, a CFTR stabilizer for Cystic Fibrosis treatment

    SBC: Calista Therapeutics, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

    SBIR Phase I 2014 Department of Health and Human Services
  9. A novel biomaterial-based therapy to prevent type 1 diabetes

    SBC: ONEVAX, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Immune-mediated diseases such as type 1 diabetes (T1D), multiple sclerosis, rheumatoid arthritis, and systemic lupus erythematosis are reaching epidemic proportions in the US. T1D affects an estimated 3 million Americans, with more than 30,000 new patients diagnosed annually, resulting in roughly 15B in health care costs in the US each year. T1D is an autoimmu ...

    SBIR Phase I 2014 Department of Health and Human Services
  10. Next-generation PERG devices and methods

    SBC: JORVEC CORP.            Topic: NEI

    DESCRIPTION (provided by applicant): Glaucoma is one of a number of optic nerve diseases which lead to retinal ganglion cells (RGC) degeneration, ultimately manifesting in a functional loss of vision if left untreated. There exist a number of therapeuticapproaches to treat these conditions, but there are currently no clinical methods to detect the onset of RGC dysfunction. The Pattern Electroret ...

    SBIR Phase I 2014 Department of Health and Human Services

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