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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Calcaftor, a CFTR stabilizer for Cystic Fibrosis treatment

    SBC: Calista Therapeutics, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

    SBIR Phase I 2014 Department of Health and Human Services
  2. Inter-alpha-inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, LLC            Topic: NINDS

    DESCRIPTION (provided by applicant): Neonatal hypoxia-ischemia (HI) remains a major cause of acute perinatal brain injury, leading ultimately to neurologic dysfunction manifesting as cerebral palsy, mental retardation, and epilepsy. Cerebral oxygen deprivation and/or reduced blood flow due to umbilical cord occlusion, prolonged labor, and/or intracranial hemorrhage produce an inflammatory respons ...

    SBIR Phase I 2014 Department of Health and Human Services
  3. IGF::OT::IGF High-Impact Substance Abuse Prevention Technologies. SBIR Phase I. Period of Performance 7/16/2014-1/15/2015

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    The overarching objective of this project is to develop an innovative technological tool that will facilitate the implementation of an evidence-based substance abuse prevention program and related health behavior risk programs among military personnel. PUBLIC HEALTH RELEVANCE

    SBIR Phase I 2014 Department of Health and Human Services
  4. Integration of Complex Geometry, 3D Woven Preforms via Innovative Stitching Technique

    SBC: T.E.A.M., INC.            Topic: H701

    Thick, 3D woven carbon/phenolic composites offer potential improvement over legacy thermal protection systems (TPS) for re-entry vehicle heat shield applications. However due to the scale and complexity of typical re-entry vehicle structures, it is likely that multiple 3D woven panels would need to laid up to create the overall heat shield, creating a potential weak spots at the panel joints. ...

    SBIR Phase I 2014 National Aeronautics and Space Administration
  5. Advancing High Energy Lithium-Sulfur Batteries

    SBC: Yardney Technical Products, Inc.            Topic: Z102

    Lithium-Ion batteries have been a main source of energy for many aerospace applications over the past decade. Future space missions are facing a number of challenging requirements, including significant increase in specific energy, approaching 500 Wh/kg, and energy density of 700 Wh/l at cell level. Compared to state-of-the-art technology today, a reduction in mass and volume are necessary, along ...

    SBIR Phase I 2014 National Aeronautics and Space Administration
  6. Low CSWAP Multi-Beam TCDL Antenna System

    SBC: APPLIED RADAR, INC.            Topic: N132089

    Applied Radar proposes to develop a high-gain low cost, size, power and weight (low-CSWAP) tactical common data link (TCDL) antenna for the Firescout and Predator UAVs. The improved TCDL antenna will support 6 or more nodes of high-gain full-duplex communication at 21.42 MBPS in a star network configuration with 360 degree coverage out to 110 nm slant range. In Phase 1, we will design, fabricate a ...

    SBIR Phase I 2014 Department of DefenseNavy
  7. Sensitive and Shape-Specific Molecular Identification

    SBC: RYON TECHNOLOGIES, INC            Topic: A11aT017

    The ability to rapidly detect, identify and monitor chemical agents remains a challenge of significant importance to the Armed Forces. Existing chemical sensing techniques have shortcomings that inhibit widespread implementation. To address this situation, Ryon Technologies is developing a portable instrument that is based on Rydberg Fingerprint Spectroscopy (RFS) in combination with mass spectrom ...

    STTR Phase II 2014 Department of DefenseArmy
  8. Low-Erosion and Affordable Nozzles for Advanced Air-to-Air Missiles

    SBC: Knobley Technical Associates LLC            Topic: N121014

    Advance the TRL level of highly-loaded rate-augmented multi-pulse reduced-signature propellant solid propulsion system nozzle technologies selected in Phase I by developing desigh architectures and a credible materials data base required to establish accurate analytical design models and verifying design/materials performance through sub-scale and full-diameter prototype motor tests.

    SBIR Phase II 2014 Department of DefenseNavy
  9. Safe, Large-Format Lithium Ion Batteries for Aircraft

    SBC: Yardney Technical Products, Inc.            Topic: AF141071

    YTP will develop technology that provides a high performance, modular Li-ion battery with: redundant safety features, safer thin, metal case cell designs; fin/micro-channel thermal control system; and an evaporating fluid system that rapidly quenches failing cells to prevent thermal runaway and fratricide. The end goal of the proposal is making a lighter, longer lasting, less expensive, safer JSF ...

    SBIR Phase I 2014 Department of DefenseAir Force
  10. Low-Profile, Broadband, Shear-Mode SONAR Transducer for Deep Submergence Applications

    SBC: Btech Acoustics, LLC            Topic: N141066

    BTech proposes the design and development of a low-profile, broadband, shear-mode piezocrystal acoustic transducer for deep submergence applications. The Phase I effort considers evaluation of design variants of shear mode transducers with increased pressure operation/tolerance and tradeoffs associated with the same. Design feasibility is supported with calculations of expected performance and whe ...

    SBIR Phase I 2014 Department of DefenseNavy

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