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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Enhancing Rural Access to Capital Through Development of a Local Crowdfunding Incubator

    SBC: LOCAL CROWD, LLC, THE            Topic: 86

    Strong rural economies need strong entrepreneurs who can start businesses and create jobs. The RUPRI Center for Rural Entrepreneurship reports that regions with high levels of entrepreneurship have 73% higher employment growth, 14% higher wage growth, 87% higher birth rate of new firms, and 45% higher productivity growth--all indicators of robust and sustainable local economies. Entrepreneurs are ...

    SBIR Phase I 2014 Department of Agriculture
  2. Glycoengineered baculoviruses for the production of more efficacious influenza va

    SBC: Glycobac, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): Vaccination significantly reduces morbidity and mortality caused by annual influenza epidemics. Traditionally, influenza vaccines have been manufactured using adapted influenza virus grown in eggs. However, this methodsuffers from inherent disadvantages such as slow production and allergenic egg proteins in the final product. To avoid these drawbacks, new vacci ...

    SBIR Phase I 2014 Department of Health and Human Services
  3. Calcaftor, a CFTR stabilizer for Cystic Fibrosis treatment

    SBC: Calista Therapeutics, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

    SBIR Phase I 2014 Department of Health and Human Services
  4. On Site Mercury Remediation via Activated Fly Ash

    SBC: POLLUTION CONTROL TECHNOLOGIES, LLC            Topic: NIEHS

    DESCRIPTION (provided by applicant): Coal-fired power plants and burners are vital drivers of the U.S. economy-but they unfortunately produce substantial amounts of mercury (Hg) that are seriously harmful to human health, particularly linked to damages ofthe nervous system. Healthcare costs due to Hg exposure are estimated to be in the billions of dollars annually. New mercury-emission regulations ...

    SBIR Phase I 2014 Department of Health and Human Services
  5. Engineering cells for concurrent protein drug biosynthesis and polysialylation

    SBC: Glycobac, LLC            Topic: NIGMS

    Project Summary / Abstract Therapeutic proteins, or biologics, represent a 100 billion market that includes drugs such as antibodies, hormones, and many others. The clinical efficacy of biologics is critically determined by their circulating half-lives.Hence, various methods have been developed to increase their circulating half-lives by reducing clearance rates. This is commonly achieved by che ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. Inter-alpha-inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, LLC            Topic: NINDS

    DESCRIPTION (provided by applicant): Neonatal hypoxia-ischemia (HI) remains a major cause of acute perinatal brain injury, leading ultimately to neurologic dysfunction manifesting as cerebral palsy, mental retardation, and epilepsy. Cerebral oxygen deprivation and/or reduced blood flow due to umbilical cord occlusion, prolonged labor, and/or intracranial hemorrhage produce an inflammatory respons ...

    SBIR Phase I 2014 Department of Health and Human Services
  7. IGF::OT::IGF High-Impact Substance Abuse Prevention Technologies. SBIR Phase I. Period of Performance 7/16/2014-1/15/2015

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    The overarching objective of this project is to develop an innovative technological tool that will facilitate the implementation of an evidence-based substance abuse prevention program and related health behavior risk programs among military personnel. PUBLIC HEALTH RELEVANCE

    SBIR Phase I 2014 Department of Health and Human Services
  8. Integration of Complex Geometry, 3D Woven Preforms via Innovative Stitching Technique

    SBC: T.E.A.M., INC.            Topic: H701

    Thick, 3D woven carbon/phenolic composites offer potential improvement over legacy thermal protection systems (TPS) for re-entry vehicle heat shield applications. However due to the scale and complexity of typical re-entry vehicle structures, it is likely that multiple 3D woven panels would need to laid up to create the overall heat shield, creating a potential weak spots at the panel joints. ...

    SBIR Phase I 2014 National Aeronautics and Space Administration
  9. Advancing High Energy Lithium-Sulfur Batteries

    SBC: Yardney Technical Products, Inc.            Topic: Z102

    Lithium-Ion batteries have been a main source of energy for many aerospace applications over the past decade. Future space missions are facing a number of challenging requirements, including significant increase in specific energy, approaching 500 Wh/kg, and energy density of 700 Wh/l at cell level. Compared to state-of-the-art technology today, a reduction in mass and volume are necessary, along ...

    SBIR Phase I 2014 National Aeronautics and Space Administration
  10. Low CSWAP Multi-Beam TCDL Antenna System

    SBC: APPLIED RADAR, INC.            Topic: N132089

    Applied Radar proposes to develop a high-gain low cost, size, power and weight (low-CSWAP) tactical common data link (TCDL) antenna for the Firescout and Predator UAVs. The improved TCDL antenna will support 6 or more nodes of high-gain full-duplex communication at 21.42 MBPS in a star network configuration with 360 degree coverage out to 110 nm slant range. In Phase 1, we will design, fabricate a ...

    SBIR Phase I 2014 Department of DefenseNavy

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