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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Innovative Designs for Reliable Electro-Explosive Ordnance Devices

    SBC: SEACORP, LLC            Topic: MDA12031

    Missiles, use electro-explosive devices (EEDs) to perform mulitple functions during operation. This effort seeks ways to improve on the EED"s reliability and lower the failure or inadvertent activation rate of these devices. During Phase I, SEA CORP investigated replacing EEDs with commercial off the shelf (COTS) automotive airbag inflators to perform the required pneumatic functions of variou ...

    SBIR Phase II 2014 Department of DefenseMissile Defense Agency
  2. Calcaftor, a CFTR stabilizer for Cystic Fibrosis treatment

    SBC: CALISTA THERAPEUTICS INC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Novel Hydrocyanine Probes for the Accurate Detection of Reactive Oxygen Species

    SBC: LI-COR BIOSCIENCES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Reactive oxygen species (ROS) are involved in numerous cell-signaling pathways. They have been implicated in over 150 diseases including cancer, arthritis, Parkinson's disease, diabetes, myocardial infarction and atherosclerosis. The need to understand the role of ROS in these processes is evidenced by the 80,000 publications in this field during the last ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Inter-alpha-inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): Neonatal hypoxia-ischemia (HI) remains a major cause of acute perinatal brain injury, leading ultimately to neurologic dysfunction manifesting as cerebral palsy, mental retardation, and epilepsy. Cerebral oxygen deprivation and/or reduced blood flow due to umbilical cord occlusion, prolonged labor, and/or intracranial hemorrhage produce an inflammatory respons ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. IGF::OT::IGF High-Impact Substance Abuse Prevention Technologies. SBIR Phase I. Period of Performance 7/16/2014-1/15/2015

    SBC: Pro-Change Behavior Systems, Inc.            Topic: NIDA

    The overarching objective of this project is to develop an innovative technological tool that will facilitate the implementation of an evidence-based substance abuse prevention program and related health behavior risk programs among military personnel. PUBLIC HEALTH RELEVANCE

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Next Generation Western for high-throughput and high-content protein analysis

    SBC: LI-COR, Inc.            Topic: 100

    DESCRIPTION provided by applicant The identification and quantification of specific proteins in complex samples are critical processes in discovering understanding and ultimately addressing the underlying nature of human health and disease The western blot is a fundamental method used for these processes due to the sensitivity and specificity enabled by combining protein sizing with immuno ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. THIS IS A PROPOSAL TO EVALUATE COMMES, A COMPUTER-BASED NURSING EDUCATIONAL CONSULTING SYSTEM, DESIGNED TO PROVIDE INDIVIDUALLY TAILORED MINICURRICULA THAT MEETS THE NEEDS OF THE NURSE USER.

    SBC: Data Management Services, Inc.            Topic: N/A

    THIS IS A PROPOSAL TO EVALUATE COMMES, A COMPUTER-BASED NURSING EDUCATIONAL CONSULTING SYSTEM, DESIGNED TO PROVIDE INDIVIDUALLY TAILORED MINICURRICULA THAT MEETS THE NEEDS OF THE NURSE USER. THE COMPUTER PROGRAM USES WORDS TYPED AT A SUITABLE TERMINAL TOGETHER WITH OPERATORS "OR", "AND", AND "INCLUDING" IN AN INQUIRY MODE TO PRODUCE A DETAILED STUDY GUIDE OF LEARNING REQUIREMENTS AND EDUCATIONAL G ...

    SBIR Phase I 1983 Department of Health and Human Services
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