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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Work Tool Innovation for Farm Land Management and Wildfire Abatement

    SBC: HILL MANUFACTURING, INC.            Topic: 812

    For rural farmers and ranchers with small and mid-sized operations who suffer losses in efficiency due to unproductive pastures and damage and property loss due to wild fires, the envisioned tree saw is an auxiliary tractor attachment with the potential to rapidly and safely remove large trees, brush, and undergrowth. Unlike current heavy and expensive attachments that require non-traditional farm ...

    SBIR Phase I 2014 Department of Agriculture
  2. Mannheimia haemolytica outer membrane vesicle-based vaccine for Shipping Fever in cattle

    SBC: Solidtech Animal Health, Inc.            Topic: 83

    "Shipping Fever" is the main cause of illness/death in beef cattle in North America, resulting in & gt;$500 million/year of losses due to treatment costs, poor weight gain, reduced carcass value and death. Mannheimia haemolyticabacteria causes the most serious form of shipping fever, causing severe, often fatal pneumonia. Because currently availableM. haemolytica vaccines are not eff ...

    SBIR Phase I 2014 Department of Agriculture
  3. Technology for Removal of Heavy Metals and Arsenic from Juice

    SBC: XPLOSAFE, LLC            Topic: 85

    The discovery that many fruit juices and brown rice syrup contain significant concentrations of arsenic or heavy metals such as lead and cadmium has raised concern amongst the public, government regulators, and food and juice producers. This contamination occurs both from natural and anthropogenic sources such as industrial pollution, arsenical herbicides and pesticides etc. While the levels of th ...

    SBIR Phase I 2014 Department of Agriculture
  4. Calcaftor, a CFTR stabilizer for Cystic Fibrosis treatment

    SBC: Calista Therapeutics, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

    SBIR Phase I 2014 Department of Health and Human Services
  5. A Wnt Modulator for Treatment of Age-related Macular Degeneration

    SBC: Charlesson, LLC            Topic: NEI

    PROJECT SUMMARY/ABSTRACT Age-related macular degeneration (AMD) is characterized by progressively decreased central vision and visual acuity and remains a leading cause of vision loss and blindness in aged Americans. Currently, the standard of care for AMD is intravitreal vascular endothelial growth factor (VEGF) inhibitors. Clinical studies have demonstrated that anti-VEGF drugs can slow or reve ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. Inter-alpha-inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, LLC            Topic: NINDS

    DESCRIPTION (provided by applicant): Neonatal hypoxia-ischemia (HI) remains a major cause of acute perinatal brain injury, leading ultimately to neurologic dysfunction manifesting as cerebral palsy, mental retardation, and epilepsy. Cerebral oxygen deprivation and/or reduced blood flow due to umbilical cord occlusion, prolonged labor, and/or intracranial hemorrhage produce an inflammatory respons ...

    SBIR Phase I 2014 Department of Health and Human Services
  7. Small blood pumps for small patients

    SBC: Vadovations, Inc.            Topic: NHLBI

    PROJECT SUMMARY/ABSTRACT Heart failure and congenital heart defects threaten the lives of several thousand children each year. The only FDA-approved long term pediatric heart support device is the Berlin Heart Excor, which is based on 30+ year old technology and is fraught with complications including blood clots forming in the device requiring frequent device replacement. The recipients of this ...

    SBIR Phase I 2014 Department of Health and Human Services
  8. IGF::OT::IGF High-Impact Substance Abuse Prevention Technologies. SBIR Phase I. Period of Performance 7/16/2014-1/15/2015

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    The overarching objective of this project is to develop an innovative technological tool that will facilitate the implementation of an evidence-based substance abuse prevention program and related health behavior risk programs among military personnel. PUBLIC HEALTH RELEVANCE

    SBIR Phase I 2014 Department of Health and Human Services
  9. Label-free platform for applications in drug discovery

    SBC: SENSIQ TECHNOLOGIES, INC.            Topic: NCATS

    DESCRIPTION: Incremental improvements in label free screening technologies over the past decade have not produced the capability necessary to support the changing needs of drug discovery programs. Persistent artifacts related to non-specific binding, promiscuous binding, precipitation, complex binding, tubing retention, aggregation, and sub-optimally designed platforms continue to hinder progress ...

    SBIR Phase II 2014 Department of Health and Human Services
  10. Integration of Complex Geometry, 3D Woven Preforms via Innovative Stitching Technique

    SBC: T.E.A.M., INC.            Topic: H701

    Thick, 3D woven carbon/phenolic composites offer potential improvement over legacy thermal protection systems (TPS) for re-entry vehicle heat shield applications. However due to the scale and complexity of typical re-entry vehicle structures, it is likely that multiple 3D woven panels would need to laid up to create the overall heat shield, creating a potential weak spots at the panel joints. ...

    SBIR Phase I 2014 National Aeronautics and Space Administration

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