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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Novel and improved extraction techniques and supply chain development for indigo crop and black walnut hull.

    SBC: STONY CREEK COLORS, INC.            Topic: 812

    The market for natural colorants is growing. Trends in food, cosmetics, and textiles show consumers are concerned over the use of synthetic, petroleum-derived dyes and seek a more environmentally friendly option. However, manufacturers cannot compromise on quality, stability, or functionality of colorants in their products. Natural colorants from plants have been used as dyes for thousands of year ...

    SBIR Phase II 2014 Department of Agriculture
  2. Calcaftor, a CFTR stabilizer for Cystic Fibrosis treatment

    SBC: Calista Therapeutics, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

    SBIR Phase I 2014 Department of Health and Human Services
  3. A new device to improve screening of corneal transplant tissue

    SBC: Sarver & Associates Inc            Topic: NEI

    Marous, James R. An Eye Bank Endothelial Cell Counter Abstract Procurement of donor corneal tissue for transplant use is an important social service undertaken by largely underfunded eye banks. Tissue is not only harvested, but must be screened for a myriad of issues that may make the tissue unsuitable for transplant or pose a health risk to the tissue recipient. Donor tissue may be rejected for ...

    SBIR Phase I 2014 Department of Health and Human Services
  4. Holographic Virtual Anatomy Table

    SBC: THIRD DIMENSION TECHNOLOGIES            Topic: NIGMS

    Project Summary/Abstract Medical students long ago gave up robbing graves for corpses, but students still need access to anatomy resources. While availability of traditional resources (e.g. cadavers, animals, etc.) is dwindling, emerging virtual alternatives are revolutionizing the practice of medicine. Interest in virtual aids derives from decades of success in aviation and the military. These in ...

    SBIR Phase I 2014 Department of Health and Human Services
  5. Inter-alpha-inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, LLC            Topic: NINDS

    DESCRIPTION (provided by applicant): Neonatal hypoxia-ischemia (HI) remains a major cause of acute perinatal brain injury, leading ultimately to neurologic dysfunction manifesting as cerebral palsy, mental retardation, and epilepsy. Cerebral oxygen deprivation and/or reduced blood flow due to umbilical cord occlusion, prolonged labor, and/or intracranial hemorrhage produce an inflammatory respons ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. Development of Compounds for the Prevention and Treatment of Rhabdomyolysis

    SBC: Virtual Drug Development Inc.            Topic: NIDDK

    ? DESCRIPTION (provided by applicant): The goal of this Phase I STTR project is to establish the feasibility of developing a small-molecule therapeutic agent designed to prevent rhabdomyolysis-induced renal failure. Rhabdomyolysis accounts for 7% to 10% of cases of renal failure in the US. Rhabdomyolysis results from muscle injury that leads to the release of myoglobin, which is then deposited ...

    STTR Phase I 2014 Department of Health and Human Services
  7. Targeting DNA damage response pathways for the treatment of advanced lung cancer

    SBC: CUMBERLAND PHARMACEUTICALS INC.            Topic: NIEHS

    DESCRIPTION (provided by applicant): There is an urgent, unmet need for novel therapeutic approaches that are efficacious against lung cancer. Ranking first among cancer deaths in the U.S., this disease has 5-year relative survival rates of lt20%. Most lung cancers are non-small cell (NSCLC, 85% of cases). Curative surgery is not an option for the 80% of NSCLC patients who present with advanced s ...

    STTR Phase I 2014 Department of Health and Human Services
  8. IGF::OT::IGF High-Impact Substance Abuse Prevention Technologies. SBIR Phase I. Period of Performance 7/16/2014-1/15/2015

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    The overarching objective of this project is to develop an innovative technological tool that will facilitate the implementation of an evidence-based substance abuse prevention program and related health behavior risk programs among military personnel. PUBLIC HEALTH RELEVANCE

    SBIR Phase I 2014 Department of Health and Human Services
  9. Lab on a chip point of care assay for the rapid serodiagnosis of Lyme disease

    SBC: Immuno Technologies, Inc.            Topic: R

    DESCRIPTION Caused by Borrelia burgdorferi Lyme disease LD can affect the skin heart joints or nervous system leading to an array of largely non specific symptoms that overlap with those of other debilitating illnesses Disease progression can lead to development of conditions with unfavorable prognosis such as antibiotic refractory arthritis or Post Treatment Lyme disease Syndrome PTLDS ...

    SBIR Phase II 2014 Department of Health and Human Services
  10. Automated Identification and Sorting of Rare Earth Elements in an E-waste Recycling Stream

    SBC: National Recovery Technologies LLC            Topic: B

    Electronic waste (e-waste) is one of the most rapidly growing waste problems worldwide. Improper handling of e-waste results in vast amounts of toxic waste being sent to landfill and leaching into the water supply. Due to these concerns, e-waste recycling is a rapidly growing industry. Unfortunately, most current e-waste recycling processes rely on either manual hand sorting or differential densit ...

    SBIR Phase II 2014 Environmental Protection Agency

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