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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Captive Reproduction, Hatchery Research and Production of Endothermic Pacific Bluefin Tuna Juveniles:Toward Responsible Pacific Bluefin Tuna Mariculture in the United States

    SBC: Ichthus Unlimited, LLC            Topic: 87

    Tuna ranching is dependent on wild-captured fish and the current operational model is largely unsustainable as it increases fishing pressure on the Pacific bluefin tuna (PBFT) wild stock. Recent ISC (International Scientific Committee for Tuna and Tuna-like Species in the North Pacific Ocean) assessments indicate that this stock is "alarmingly overfished", while experiencing high exploitation rate ...

    SBIR Phase I 2018 Department of Agriculture
  2. Broadly protective porcine Streptococcus suis vaccines

    SBC: PATHOVACS INCORPORATED            Topic: 83

    Non-technical SummaryCurrently, there are no efficacious vaccines to protect piglets against disease caused by the emerging zoonotic (transmissible from animals to humans) pathogen, Streptococcus suis. Porcine S. suis disease is a major cause of morbidity and mortality in weaned piglets and is a significant economic burden on pork producers globally. Losses to the pig industry globally are in the ...

    SBIR Phase I 2018 Department of Agriculture
  3. STEM lesson creation coaching framework to improve the pedagogy of K-5 teachers implementing the Next Generation Science Standards (NGSS)

    SBC: StarrMatica Learning Systems, Inc.            Topic: 86

    High-quality schools positively influence the economic development prospects in rural areas by attracting business and industry to the area and producing the educated labor force that is needed to sustain economic growth. The greatest source of a highly educated population in rural areas is native individuals who attended college locally or who return home after completing their education elsewher ...

    SBIR Phase I 2018 Department of Agriculture
  4. Culturally Aware Entrepreneurial Education

    SBC: Independent Platform, LLC            Topic: 86

    This proposal is a response to the Rural and Community Development needs outlined in the RFP to focus on efforts needed to enhance human capital development, build earnings capacity, increase labor force participation and/or promote job creation to the most vulnerable populations in rural communities. The Navajo community drastically underperforms the nation in creation of businesses and jobs for ...

    SBIR Phase I 2018 Department of Agriculture
  5. Customizable Science Informational Texts to Support K-5 Teachers Implementing the Common Core and NGSS

    SBC: StarrMatica Learning Systems, Inc.            Topic: 86

    Today's elementary teachers must address the needs of an increasingly diverse population of students--ranging from those who enter their classrooms reading at many years below grade level to those who are many years above grade level. This discrepancy is often the most profound in rural school districts. This impacts teachers' abilities to help students acquire strong skills in reading--fo ...

    SBIR Phase II 2018 Department of Agriculture
  6. New Biotechnology using MicroRNA Inhibitors to Regenerate Alveolar Bone

    SBC: Naturemiri, LLC            Topic: 100

    Summary AbstractDental implants are becoming an increasingly popular option vsdenturesbridgesand other dentalprosthetics due to greater patient satisfaction and better longterm outcomesHoweverosseointegrateddental implants require stronghealthy bone for implantation to be successfulWhile success rates forosseointegrated dental implants are relatively higha drastic increase in the number of implant ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. New Technology to Improve Chemotherapy Safety for Cancer Patients and Health Workers

    SBC: J & J Solutions, Inc.            Topic: 101

    PROJECT ABSTRACTManual drug compounding of chemotherapy medications permits deadly dosing errors and toxic drug exposureposing unnecessary risks to patients and healthcare workersSome automated drug compounding devices have been developed in responsehoweverpoor drug containment safety capabilities and prohibitive cost and size have limited widespread adoption of existing compounding devicesCorvida ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Development of a syringe/sonication device employed to administer DDFPe in the prehospital setting

    SBC: NUVOX PHARMA, L.L.C.            Topic: 101

    PROJECT SUMMARY ABSTRACT Clinical ChallengeIn acute traumain the civilian settinghemorrhage is the second most leading cause of deathIn the military settingof potentially preventable deaths are caused by hemorrhage due to traumaof civilian andof military mortality caused by traumatic hemorrhage occurs pre hospitalizationAdverse outcome in trauma patients during prehospital resuscitation is due to ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Novel Targeting of the S1P Receptor, S1P1, and Nox4 as Therapeutic Approaches in ARDS

    SBC: RESTORE THERAPEUTICS LLC            Topic: NHLBI

    PROJECT SUMMARYAcute Respiratory Distress SyndromeARDSis a devastating syndrome that afflicts more thanpatients in United States alone and has an unacceptably high mortality rate ofCurrently there are no therapies that address the loss of lung vascular barrier integrityvascular leakage and alveolar flooding that are critical features of ARDS pathobiologyThe PI was the first to demonstrate that sph ...

    STTR Phase I 2018 Department of Health and Human Services
  10. Preclinical studies of Selective and Orally Bioavailable Aurora B Inhibitors for the Treatment of AML

    SBC: SYNACTIX PHARMACEUTICALS, INC.            Topic: 102

    ABSTRACTThe Aurora Kinase FamilyAKFcomprises heavily pursued therapeutic targets for cancer because of their intimate involvement in cell division and tumor progressionNumerous therapeutic campaigns have been initiated against the AKFwith promising clinical successes emanating from strategies targeting either Aurora A or Aurora BHoweverthe US Food and Drug Administration has yet to approve a cance ...

    STTR Phase I 2018 Department of Health and Human Services

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