List

A Multimodal Acoustic Tool for Inline Pipe Inspection 3/19/2018 The US energy transport pipeline system is a longstanding distribution network with most of its still standing pipes being installed between the 1950s–1970s. Due to degradation mechanisms, such as embrittlement, capable of causing a two-fold reduction in fracture toughness, pipe rupture is a major risk. Current nondestructive ins ...

Proposal title: Rapid Assessment of Air Void System in Fresh Concrete Water expansion during freeze-thaw cycles can cause deterioration in concrete, leading to scaling, cracking, and crumbling over a period of years. Resistance to this damage is achieved with a system of voids formed by adding surfactants to the fresh concrete to stabilize air bubbles naturally entrained during mixing. The volume ...

Proposal title: Broken Rail Detection from Flashing Rear End Device Broken rails are a common cause of mainline derailments and a particular concern given the increasing use of our rail system for passenger traffic and petroleum products. The progressive nature of the defects provides an opportunity for early detection of cracks before they become significant enough to cause a derailment. Unfortu ...

INRS and MDP will collaborate to build an analytical model that demonstrates the probability of success - and opportunities for enhancement - for the redevelopment of idled industrial assets. This model will be developed and refined using the former pulp and paper mill in Old Town, ME., and data supplied by multiple redevelopment efforts elsewhere in the State of Maine. Based upon learnings and ex ...

This proposal is a response to the Rural and Community Development needs outlined in the RFP to focus on efforts needed to enhance human capital development, build earnings capacity, increase labor force participation and/or promote job creation to the most vulnerable populations in rural communities. The Navajo community drastically underperforms the nation in creation of businesses and jobs for ...

Project SummaryAbstract The goal of this Phase I work is to finish development of an innovative interactive app designed to help patients appropriately use total knee replacementTKRsurgery and provide support to achieve best outcomesTKR is highly effective for treating advanced osteoarthritis of the kneebut it has risksAppropriate use can be assured by engaging patients in a Shared Decision Making ...

PROJECT SUMMARY ABSTRACTMillions of children around the globe are afflicted with conditions that can alter neuropsychological developmentincluding human immunodeficiency virusHIVtraumatic brain injuryTBIcerebral malariaand a host of other developmental and acquired diseases and disordersEarly assessment and intervention are critical in overcoming cognitive and developmental deficiencies and are in ...

PROJECT SUMMARY ABSTRACT Clinical ChallengeIn acute traumain the civilian settinghemorrhage is the second most leading cause of deathIn the military settingof potentially preventable deaths are caused by hemorrhage due to traumaof civilian andof military mortality caused by traumatic hemorrhage occurs pre hospitalizationAdverse outcome in trauma patients during prehospital resuscitation is due to ...

PROJECT SUMMARYAcute Respiratory Distress SyndromeARDSis a devastating syndrome that afflicts more thanpatients in United States alone and has an unacceptably high mortality rate ofCurrently there are no therapies that address the loss of lung vascular barrier integrityvascular leakage and alveolar flooding that are critical features of ARDS pathobiologyThe PI was the first to demonstrate that sph ...

ABSTRACTThe Aurora Kinase FamilyAKFcomprises heavily pursued therapeutic targets for cancer because of their intimate involvement in cell division and tumor progressionNumerous therapeutic campaigns have been initiated against the AKFwith promising clinical successes emanating from strategies targeting either Aurora A or Aurora BHoweverthe US Food and Drug Administration has yet to approve a cance ...