Award Data

Circular RNAs (circRNAs) are a novel class of non-coding RNAs that are an abundant component of the epitranscriptome. Putative functions of circRNAs, include miRNA sequestration, RNA-binding protein scaffolding, mRNA trapping, and protein translation regulation. Deregulation in one or more of these roles has been linked to several types of cancer, including pancreatic cancer, basal cell carcinoma, ...

The trend over the last several years is fewer businesses supplying manufactured products. Thus, by supply and demand, the cost of military hardware has increased with less competition. Furthermore, amortized cost of the qualifying a new product becomes cost prohibited resulting in non-competitive bids compared to historical averages. DLAs Replenishment Parts Purchase or Borrow program supports re ...

ORBIS proposes to Address SBIR DLA171-002 by developing efficient and effective processes to reverse engineer RPPOB Candidate Items. ORBIS has a wealth of experience in supporting DoD systems and components and is well suited to addressing the backlog of unsupported equipment .

A technical approach is proposed to survey the industry for state of the art capabilities in terms of the SOCOM mission requirements described in the solicitation for the Group 2 Tactical ISR UAS. The results of the survey will select a configuration of potential candidate UAS that would meet the threshold and ultimately objective goals stated.

This STTR Phase I project will undertake the development of iron coordination complexes as alternatives for gadolinium contrast agents which are currently used in clinical MRI diagnostic exams. New MRI contrast agents are needed to serve the segment of the population who cannot tolerate Gd(III) agents. This includes patients with kidney disease and those who have frequent MRI scans and may accumul ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project will serve two complementary unmet market needs by: (1) accelerating the evaporation rate of brine ponds and enhancing salt production efficiency by 2-3 times; (2) condensing the moisture evaporated from contaminated/salty water so that one can obtain clean drinking water with n consumption of ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is to produce polymer composites that enable commercialization of alkaline electrochemical devices, such fuel cells and electrolyzers. The use of fuel cell technologies will help preserve the environment, mitigate climate change, decreasing our carbon footprint and securing renewable energy supply. El ...

This Small Business Innovation Research Phase I project will demonstrate feasibility of the first metrology system capable of quantifying surface roughness in three dimensions in situ in production environments. Current shop floor systems are almost entirely two-dimensional stylus-based systems that are fragile, incapable of measuring complex geometries and have high cost of ownership. A shop-floo ...

This Small Business Innovation Research Phase I project is aimed at developing a superior platform for the preparation of samples for cryogenic Transmission Electron Microscopy (cryo-TEM). Cryo-TEM provides images of morphologies and structures of liquid-based samples with nanometer resolution, which provides crucial insight for the development of materials in the pharmaceutical, chemicals and con ...

The broader impact of this Small Business Innovation Research (SBIR) Phase I project is to equip consumers with a scientific tool to measure and control their exposure to ultraviolet (UV) radiation, thereby mitigating their risk of getting skin cancer while enjoying the benefits of sunlight such as Vitamin D and outdoors activities. In the United States, skin cancer has become a major public healt ...