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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Spirulina-based oral vaccine for infectious hematopoietic necrosis virus (IHNV) in farmed salmonid fish

    SBC: Lumen Bioscience, Inc.            Topic: 87

    Non-Technical SummaryAquaculture is the fastest growing segment of the global food industry and plays an increasingly important role in feeding the world's population. Intensive aquaculture using increased stocking densities, compressed rearing cycles, monocultures, antibiotics, and other strategies aimed at efficient protein production has been complicated by outbreaks of known and newly emer ...

    SBIR Phase I 2018 Department of Agriculture
  2. Tick Surveillance and Mass Capture Trap

    SBC: Springstar, Inc.            Topic: 83

    To this date there are no commercially available tick traps. A simple tick trap will provide a method for detection of ticks that users can use to make informed decisions about timing appropriate pesticide applications, thus minimizing total pesticide use. Additionally, the traps can be deployed to mass-capture ticks, so that the devices can provide a pesticide-free intervention for controlling ti ...

    SBIR Phase I 2018 Department of Agriculture
  3. Culturally Aware Entrepreneurial Education

    SBC: Independent Platform, LLC            Topic: 86

    This proposal is a response to the Rural and Community Development needs outlined in the RFP to focus on efforts needed to enhance human capital development, build earnings capacity, increase labor force participation and/or promote job creation to the most vulnerable populations in rural communities. The Navajo community drastically underperforms the nation in creation of businesses and jobs for ...

    SBIR Phase I 2018 Department of Agriculture
  4. Scale up and commercialization of high performance biocomposite structures

    SBC: Grow Plastics LLC            Topic: 88

    Grow Plastics has a technology that has been demonstrated to generate sandwich core structures in thermoplastic products. This efficient structure allows the generation of plastic products which are equivalent in strength to solid products, yet use 1/3 of the material. This substantial material reduction allows the production of parts that are lower environmental impact (due to source reduction) a ...

    SBIR Phase II 2018 Department of Agriculture
  5. RECAL:A New Tool for Disease Detection and Biomolecular Imaging

    SBC: Photon Biosciences LLC            Topic: 400

    Project SummaryAbstract We envision developing a new ultrasensitive detection platform that combines a recombinant protein with a unique imaging media that results in a luminescent protein that is non bleaching and non blinkingThe excitation and emission wavelengths of this protein can be tuned with the choice of imaging media and span much of the visible and near infrared regions of the electroma ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. Real-Time Salivary Testosterone and Extension to Mobile Application and Multiple Biomarker Quantification Capability

    SBC: OASIS DIAGNOSTICS CORPORATION            Topic: NIDA

    Program Director Principal InvestigatorLastFirstMiddleSloweyPaul DAbstract This phase I NIH SBIR proposal seeks support for an interdisciplinary partnership between Oasis Diagnosticsand Iowa State University who collaboratively seek to develop a novel tool that can measure and quantify levels of the sex hormone testosterone in saliva within minutes of collectionVerOFytestosteroneThe FDA has urged ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Development of an alpha-conotoxin RgIA analog as a novel, non-opioid therapeutic for chronic neuropathic pain

    SBC: KINETA, INC.            Topic: NIDA

    PROJECT SUMMARY The objective of this SBIR Phase I application is to select an optimized lead analog ofconotoxin RgIA to develop as a uniquenon opioid therapeutic for chronic neuropathic painRgIAa peptide derived from the predatory marine cone snail Conus regiusis an inhibitor of thenicotinic acetylcholine receptornAChRa novel genetically validated pain targetOur current lead candidateKCPpotently ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Development of a syringe/sonication device employed to administer DDFPe in the prehospital setting

    SBC: NUVOX PHARMA, L.L.C.            Topic: 101

    PROJECT SUMMARY ABSTRACT Clinical ChallengeIn acute traumain the civilian settinghemorrhage is the second most leading cause of deathIn the military settingof potentially preventable deaths are caused by hemorrhage due to traumaof civilian andof military mortality caused by traumatic hemorrhage occurs pre hospitalizationAdverse outcome in trauma patients during prehospital resuscitation is due to ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Novel Targeting of the S1P Receptor, S1P1, and Nox4 as Therapeutic Approaches in ARDS

    SBC: RESTORE THERAPEUTICS LLC            Topic: NHLBI

    PROJECT SUMMARYAcute Respiratory Distress SyndromeARDSis a devastating syndrome that afflicts more thanpatients in United States alone and has an unacceptably high mortality rate ofCurrently there are no therapies that address the loss of lung vascular barrier integrityvascular leakage and alveolar flooding that are critical features of ARDS pathobiologyThe PI was the first to demonstrate that sph ...

    STTR Phase I 2018 Department of Health and Human Services
  10. Design and Optimization of Clinical Gene Gun for Delivery of Nucleic Acid Vaccines

    SBC: Orlance, Inc.            Topic: NIAID

    Gene gun delivery of DNA vaccinesalso known as particle mediated epidermal delivery or PMEDdelivers DNA vaccines coated ontomicron sized gold particles directly into cells of the epidermisIt achieves pain free deliveryis considerably more efficient than electroporation or other DNA vaccine delivery approachesrequiresfold lower dosesand induces both systemic and mucosal responsesThe gene gun stands ...

    SBIR Phase I 2018 Department of Health and Human Services

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