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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. SBIR Phase II: Optimization of Rotavirus Vaccine Production

    SBC: Meridian Life Sciences, Inc.            Topic: N/A

    To improve the safety and efficacy of oral rotavirus vaccines, CDC scientists have developed a proprietary inactivated rotavirus vaccine (IRV) technology (new human strains and a novel method for rotavirus inactivation) and demonstrated the immunogenicity in mice [14] and protective efficacy in piglets [15] of this IRV by intramuscular (IM) administration. More recently, CDC scientists have demons ...

    SBIR Phase II 2014 Department of Health and Human Services
  2. IGF::OT::IGF-- Biomarkers for Alcohol and ALD

    SBC: ECHELON BIOSCIENCES, INC.            Topic: NIAAA

    This contract addresses the need for reliable and accurate biomarkers of alcohol consumption, initially in response to a National Institute on Alcohol Abuse and Alcoholism (NIAAA)-initiated Small Business Innovation Research (SBIR) contract topic on Biomarkers for Alcohol-induced Disorders. The goals of this contract are to advance the usefulness of phosphatidylethanol (PEth), an alcohol metabolit ...

    SBIR Phase II 2014 Department of Health and Human Services
  3. HHSN261201400049C; TOPIC 309- DEVELOPMENT OF LOW COST, SMALL SAMPLE MULTI-ANALYTE TECHNOLOGIES FOR CANCER DIAGNOSIS, PROGNOSIS AND EARLY DETECTION; TITLE: LOW-VOLUME, ULTRA-SENSITIVE IMMUNODIAGNOSTIC

    SBC: SILOAM BIOSCIENCES            Topic: NCI

    Not Available

    SBIR Phase II 2014 Department of Health and Human Services
  4. IGF::OT::IGF SBIR Topic 66 Phase II: Haptoglobin Treatment to Reduce Complications of Sickle Cell Disease

    SBC: NANOSHELL COMPANY, LLC            Topic: NHLBI

    Not Available

    SBIR Phase II 2014 Department of Health and Human Services
  5. Helium Free MRI Image Guided Radiation Therapy (IGRT) System for ViewRay Inc

    SBC: HYPER TECH RESEARCH, INC.            Topic: NCI

    ? DESCRIPTION (provided by applicant): This NIH Bridge Grant will result in a conduction cooled, liquid helium free, MRI background magnet for a commercial image guided radiation treatment (IGRT) for cancer treatment. The program will ensure the successful continued commercialization of our customer's image guided radiation therapy (IGRT) system, a vital cancer treatment device now treati ...

    SBIR Phase II 2014 Department of Health and Human Services
  6. Miniature Stimulator for Temporary Therapies

    SBC: SPR THERAPEUTICS, INC.            Topic: NICHD

    DESCRIPTION (provided by applicant): The goal of this project is to collect the safety and effectiveness clinical data necessary to commercialize the SMARTPATCH(R) system for post-stroke shoulder pain (PSSP). The prevalence of stroke is approximately 8 million in the US, with 795,000 additional persons surviving a stroke each year. Moderate to severe shoulder pain develops in a quarter to a third ...

    SBIR Phase II 2014 Department of Health and Human Services
  7. Alternative Pathway Inhibitors for Orphan Indication

    SBC: Novelmed Therapeutics Inc            Topic: NHLBI

    DESCRIPTION (provided by applicant): Paroxysmal Nocturnal Hemoglobinuria (PNH) is an orphan disease characterized by severe anemia, kidney and liver failure, and ultimately death, if left untreated. In 2007, FDA approved the first complement inhibitor, Eculizumab (Soliris(R)), for the treatment of PNH. Eculizumab binds to C5 and prevents C5 cleavage and the formation of C5b-9, a complement product ...

    SBIR Phase II 2014 Department of Health and Human Services
  8. Epoch Telemetry System for Long-Term Monitoring of Biopotentials

    SBC: EPITEL, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): Epoch Telemetry System for Long-Term Monitoring of Biopotentials ABSTRACT Epoch is a wireless, multi- channel biopotential recording system designed for small animal translational research models of human disease developed in Phase I and II. Obtaining long- term continuous recordings from animal models of disease is a critical component of translational resear ...

    SBIR Phase II 2014 Department of Health and Human Services
  9. Health Effects of CREON2000 in Asthmatic Children

    SBC: GENERAL INNOVATIONS AND GOODS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The purpose of this trial is to investigate the effectiveness of the CREON2000A for improving asthma control and preventing or reducing asthma events in children with mild to moderate allergic asthma. The patented CREON2000A device is being developed as an environmental control intervention that will serve as an adjunctive treatment of asthma. The compact energ ...

    SBIR Phase II 2014 Department of Health and Human Services
  10. Backbone Degradable Polymer-drug Conjugates for the Treatment of Ovarian Cancer

    SBC: TheraTarget, Inc.            Topic: NCI

    DESCRIPTION provided by applicant The purpose of this Phase II STTR project is to develop a polymeric system for the combination delivery of two antineoplastic agents gemcitabine and paclitaxel Based on the successful results of the STTR Phase I award this Phase II proposal details the rationale and research plan for the synthesis and evaluation of in vivo efficacy of two novel macromolecula ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health

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