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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Enhanced Radiation Attenuation Medical Gloves

    SBC: EnergyEne Inc.            Topic: 88

    High margin, low volume, specialty rubber product markets are critical to early stage commercialization of guayule natural rubber, a domestic rubber source. Current guayule production is too small to achieve economies of scale and cannot compete in the low cost, high volume, commodity markets. This project exploits the unique mechanical properties of guayule latex to develop the first radiation at ...

    SBIR Phase I 2018 Department of Agriculture
  2. Virus-like-particle (VLP) vaccine for chicken infectious anemia.

    SBC: LARAD Inc.            Topic: 83

    The human population relies on food animals as a major source of high quality protein. Maintaining the health of these animals is of critical importance to good human nutrition worldwide. Chicken anemia virus (CAV) is an important immunosuppressive pathogen of poultry. We are proposing to improve vaccines and diagnostics for this pathogen to improve animal health. Chicken infectious anemia (CIA) i ...

    SBIR Phase II 2018 Department of Agriculture
  3. A New Nano-Based Detector for the Indian Meal Moth, Both Adult Insects and Larva

    SBC: SENSOR DEVELOPMENT CORPORATION            Topic: 85

    The problem of losses due to insect and microbiological pests does not end in the field or with the harvest. The problem persists into the storage phase where the value of raw commodities is reduced by direct damage. Thus sensing and eliminating insect pests must be accomplished to ensure not only the retention of maximum value of the crop but also to permit the safe movement of agricultural commo ...

    SBIR Phase II 2018 Department of Agriculture
  4. The Bimodal Ankle: Development and Engineering Validation of a Hydraulic Actuator

    SBC: OHIO WILLOW WOOD COMPANY, THE            Topic: na

    This project designs, fabricates, and completes engineering verification of a hydraulic actuator for a novel prosthetic ankle-foot system. The goal of this project is to improve balance and balance confidence of persons with lower extremity amputations by developing a prosthetic ankle that has biomimetic modes for walking and standing. This bimodal ankle provides flexibility for walking mobility a ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Rapid response toxicology prediction platform

    SBC: LEADSCOPE, INC.            Topic: NIEHS

    Project Summary Abstract In silico toxicology is an important alternative approach to animal testing that provides a fast and inexpensive prediction of toxicityIt uses computer models to predict whether a chemical is safe or if there is a potential hazardIn silico methods are particularly valuable when a decision needs to be made quicklysuch as for an emergency response to a chemical spill or when ...

    SBIR Phase II 2018 Department of Health and Human Services
  6. Development and validation of a novel non-invasive device for measuring the mechanical properties of cortical bone

    SBC: AEIOU Scientific LLC            Topic: NIA

    Abstract AEIOU ScientificLLCAEIOUaims to develop and commercialize Ohio Universityandapos sOHIOandapos spatent pending Cortical Bone Mechanics TechnologyCBMTas a non invasive medical device for improving the diagnosis and monitoring of osteoporosis and other bone diseasesOsteoporosis and low bone mass affectmillion Americans andmillion people worldwideIn womenthe resulting fragility fractures caus ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Production and Characterization of Human Immunoglobulin Producing Goats for Diagnostic Reagents and Therapeutics

    SBC: SAB Capra LLC            Topic: NIAID

    Project Summary A research plan is proposed to engineer goats that produce fully human immunoglobulinThese animals will be evaluated as a candidate platform system for production of both targeted therapeutic immunoglobulin as well as reagent antibodies for standards and controls of serological assays of human clinical samplesPrevious studies have demonstrated that ungulates such as cattle can prod ...

    STTR Phase I 2018 Department of Health and Human Services
  8. The Kappa Partial Agonist PPL-103 as a Potential Cocaine Abuse Pharmacotherapy

    SBC: PHOENIX PHARMALABS, INC.            Topic: NIDA

    Abstract Currentlyclinically used drug abuse medications exist for treatment of addiction to opiatesalcoholand nicotinebut not cocaineThe objective of the proposed project is to test the hypothesis that the partial kappa agonist PPLcan be effective as a pharmacotherapy for treatment of cocaine abuseBecause of chronic drug induced changes in the kappa opioid receptor systemkappa receptor directed c ...

    STTR Phase I 2018 Department of Health and Human Services
  9. Humanized EMAP II mAb as a Novel Therapy for Viral-Associated Lung Injury

    SBC: Allinaire Therapeutics, LLC            Topic: NHLBI

    Summary Abstract The ultimate goal of this project is the validation of a humanized endothelial monocyteactivating protein IIEMAP IIneutralizing monoclonal antibodymAbfor progression to clinical evaluation as a novel treatment for patients with influenza associated lung injuryInfection with influenza virusIAVremains a major world wide health threat to high risk populations including the young and ...

    STTR Phase I 2018 Department of Health and Human Services
  10. 3D Holographic Guidance, Navigation, and Control (3D GN&C) for Endovascular Aortic Repair (EVAR)

    SBC: Centerline Biomedical, Inc.            Topic: NHLBI

    Project Summary This project will develop newD visualization to improve stent graft deployment during minimally invasive endovascular aortic repairEVARby overcoming limitations ofD x ray fluoroscopyfluoroD holographic guidancenavigation and controlD GNandamp Cwill be provided to decrease fluoro radiation dose burden to patients and OR staff during treatment of aortic aneurysmsparticularly when dep ...

    STTR Phase I 2018 Department of Health and Human Services

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