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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Randomized Prospective Phase II Clinical Trial of NVX-108 in Association with Chemoradiation of Glioblastoma

    SBC: NUVOX PHARMA, L.L.C.            Topic: 102

    Glioblastoma multiforme (GBM) is a malignant primary brain tumor affecting about 12,000 new cases per year in the U.S. Average survival is only about 14-15 months. Radiation (RT) is most commonly administered as 30 fractions of 2 Gray each over 6-weeks with concomitant temozolomide (TMZ). GBM tumors are hypoxic. The primary mechanism of RT is creation of singlet oxygen; hypoxia within GBM adversel ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. An Integrated Microarray Printing and Detection System

    SBC: BIOSENSING INSTRUMENT INC            Topic: 400

    DESCRIPTIONprovided by applicantMicroarray technology has dramatically advanced the study of protein interactions leading to discovery and validation of new biomarkers and therapeutic drugsTypicallyprotein microarrays are pre spotted with target molecules in one device and then tested with probe molecules using another deviceDuring each testing cyclethe entire microarray becomes exposed to the pro ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. STTR Phase I: Novel Radar Using 3D Printed Luneburg Lens for Autonomous Transportation

    SBC: LUNEWAVE INC.            Topic: EW

    The broader impact/commercial potential of this project is significant. The research results will address the resolution and detection speed requirements of autonomous driving in complex environments such as urban scenarios. The next major revolution of transportation is undoubtedly autonomous driving which will bring great potential benefits in terms of safety, mobility and related productivity. ...

    STTR Phase I 2017 National Science Foundation
  4. SBIR Phase I: Novel Plasma Actuator for Improved Wind Turbine Performance

    SBC: AQUANIS, INC.            Topic: MI

    The broader impact/commercial potential of this project is the reduction in the cost of renewable energy. The dramatic decline in the cost of wind energy over the last several decades has been fueled by the ever increasing turbine size and the introduction of new manufacturing methods and materials. However, the industry is approaching the limits of this trend due to the increased wear and tear of ...

    SBIR Phase I 2017 National Science Foundation
  5. SBIR Phase I: High multiplex visual mapping of heterogeneity in FFPE biospecimen

    SBC: BIOSYNTAGMA, LLC            Topic: BM

    This SBIR Phase I project will address drug resistance in cancer patients through the advanced analysis of biopsies. Not only is each patient unique but their tumor contains a high level of genetic diversity as well. Overlooked diversity within patient tumors can lead to inadequate treatment and consequently acquired drug resistance, and has also been shown to predict therapeutic response to certa ...

    SBIR Phase I 2017 National Science Foundation
  6. SBIR Phase I: In-line sensor for monitoring monoclonal antibody production based on hydrogels containing peptide aptamers

    SBC: APPLIED BIOSENSORS, LLC            Topic: BM

    This SBIR Phase I project will benefit society by reducing the cost of manufacturing biologic pharmaceuticals and improving their quality, including pharmaceuticals that are currently too costly to manufacture because they target relatively small patient populations. The proposed innovation will advance state-of-the-art by providing a continuous in-situ multi-analyte sensor enabling novel methods ...

    SBIR Phase I 2017 National Science Foundation
  7. SBIR Phase I: Weft: Simulation Software for Textile Design and Manufacturing

    SBC: COMPUTATIONAL TEXTILES, INC.            Topic: IT

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to revolutionize the way that woven textiles are designed and manufactured. The textile industry is currently organized around fixed catalogs of fabrics, with significant barriers to the introduction of new products, including limited access to industrial equipment. The project will create ...

    SBIR Phase I 2017 National Science Foundation
  8. STTR Phase I: Nondestructive high-resolution measurement of semiconductor carrier density

    SBC: NEWPATH RESEARCH LLC            Topic: MI

    This Small Business Technology Transfer Phase I project will develop advanced tools for semiconductor metrology that are essential for high accuracy at finer resolution as progress continues to the finer lithography nodes. This progress is essential to satisfy the demand for greater performance in numerous consumer products as well as many other applications. The intellectual merit of this project ...

    STTR Phase I 2017 National Science Foundation
  9. SBIR Phase II: Quasi-Active Prosthetic Ankle System: Dynamic Angle and Stiffness Optimizations for Multiple Gait Activities

    SBC: Springactive, Inc.            Topic: EW

    The broader impact/commercial potential of this project is that the proposed system will enhance the ability of the 1.3 million people currently living in the United States with a lower limb amputation to walk in unconstrained environments. The proposed Quasi-Active Prosthetic Ankle System (QPAS) addresses the RH6: Human Assistive Technologies area. QPAS will be lightweight, have a long battery li ...

    SBIR Phase II 2017 National Science Foundation
  10. High throughput multiplexed characterization and modeling of antibody antigen binding with application to HSV

    SBC: Carterra, Inc.            Topic: NIAID

    Abstract All therapeutic antibodies and most vaccines critically depend on the ability of antibodies to specifically recognize particular antigens consequently detailed characterization of antibody antigen binding can provide invaluable information to understand and guide development Unfortunately due to the time and expense required atomic resolution structure determination is typically use ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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