List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Calcaftor, a CFTR stabilizer for Cystic Fibrosis treatment

    SBC: Calista Therapeutics, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

    SBIR Phase I 2014 Department of Health and Human Services
  2. Inter-alpha-inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, LLC            Topic: NINDS

    DESCRIPTION (provided by applicant): Neonatal hypoxia-ischemia (HI) remains a major cause of acute perinatal brain injury, leading ultimately to neurologic dysfunction manifesting as cerebral palsy, mental retardation, and epilepsy. Cerebral oxygen deprivation and/or reduced blood flow due to umbilical cord occlusion, prolonged labor, and/or intracranial hemorrhage produce an inflammatory respons ...

    SBIR Phase I 2014 Department of Health and Human Services
  3. IGF::OT::IGF High-Impact Substance Abuse Prevention Technologies. SBIR Phase I. Period of Performance 7/16/2014-1/15/2015

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    The overarching objective of this project is to develop an innovative technological tool that will facilitate the implementation of an evidence-based substance abuse prevention program and related health behavior risk programs among military personnel. PUBLIC HEALTH RELEVANCE

    SBIR Phase I 2014 Department of Health and Human Services
  4. Lung nodule detection using 3D visual palpation via standard thoracoscopes

    SBC: LUCIDUX            Topic: NIBIB

    DESCRIPTION (provided by applicant): Surgeons perform tens of thousands of operations each year to resect suspicious lung nodules. Historically this necessitated an open surgical approach (thoracotomy) through a large chest wall incision. Over the last 10-15 years, minimally invasive surgical (MIS) approaches have become increasingly common in abdominal and thoracic surgery, with significant benef ...

    SBIR Phase I 2011 Department of Health and Human Services
  5. Development of a Topical Choroid Plexus Factor Product to Accelerate Wound Healin

    SBC: CYTOSOLV INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Chronic superficial wounds are difficult to treat and often never completely heal. Diabetic foot complications account for the majority of lower limb amputations in the world, and 25% of all diabetic hospital admissionsin the US. The standard of care for these wounds has been unchanged for decades, and remains reduced weight bearing, debridement, antibiotics, a ...

    SBIR Phase I 2011 Department of Health and Human Services
  6. Treatment of stroke using a novel PDZ binding peptidomimetic drug.

    SBC: Ardane Therapeutics Inc.            Topic: NINDS

    DESCRIPTION (provided by applicant): Abstract Stroke is the third leading pathological cause of death, behind heart and cancer (NCHS mortality data.). We are developing a new drug, CN 2097, that has demonstrated therapeutic potential for stroke. CN 2097 obstructs the propagation of the cell death signal whilst not interfering with normal neuronal transmission, thus reducing the incidence of si ...

    SBIR Phase I 2011 Department of Health and Human Services
  7. Autonomous Power Management for Hearing Aids and Hearing Products

    SBC: PACKET DIGITAL LLC            Topic: NIDCD

    DESCRIPTION (provided by applicant): Loss of hearing affects the quality of life for individuals. The number of Americans with hearing loss is increasing as baby boomers age and younger citizens damage their hearing with personal audio devices. By 2025, approximately 40 million Americans are projected to be hearing impaired, an increase of 23% from current numbers. Hearing loss may be treated, but ...

    SBIR Phase II 2011 Department of Health and Human Services
  8. Phase II: A multi-user virtual Biology environment for discovery-oriented science

    SBC: WOWIWE INSTRUCTION COMPANY            Topic: NCRR

    DESCRIPTION (provided by applicant): This SBIR Phase II project, A multi-user virtual Biology environment for discovery-oriented science education , is intended for consideration under the NIH Development of Discovery-Oriented Software and Tools for Science Education category through the National Center for Research Resources (NCRR) following a Phase I project with the same title. The Virtual Cel ...

    SBIR Phase II 2011 Department of Health and Human Services
  9. A STUDY IS PROPOSED WHICH WILL DETERMINE THE FEASIBILITY OF DEVELOPING A COMPUTER BASED MODEL FOR ADMINISTERING ASSESSMENT AND THERAPY TO MENTALLY RETARDED/DEVELOPMENTALLY DISABLED INFANTS AND CHILDREN.

    SBC: Handicapped Childrens Technolo            Topic: N/A

    A STUDY IS PROPOSED WHICH WILL DETERMINE THE FEASIBILITY OF DEVELOPING A COMPUTER BASED MODEL FOR ADMINISTERING ASSESSMENT AND THERAPY TO MENTALLY RETARDED/DEVELOPMENTALLY DISABLED INFANTS AND CHILDREN. THE PRINCIPAL AIM OF PHASE I IS TO SURVEY CURRENT TECHNOLOGIES AS THEY RELATE TO THERAPY AND PROVIDE A BASIS FOR A PHASE II RESEARCH PLAN. HARDWARE AND SOFTWARE BASED SIMULATION OF A MODEL WILL BE ...

    SBIR Phase I 1985 Department of Health and Human Services
  10. LIPID INCORPORATED SERUM-FREE MEDIUM

    SBC: Oncology Laboratorytory, In            Topic: N/A

    N/A

    SBIR Phase I 1985 Department of Health and Human Services

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government