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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Commercializing the Effective K-3 Assessment to Instruction (A2i) Intervention to Reduce Cost and to Scale Access to the Benefit of More Students

    SBC: Learning Ovations, Inc.            Topic: N/A

    Purpose: Students who fail to achieve proficient levels of literacy are at increased risk for grade retention, referral to special education, and dropping out of high school. The kindergarten through 3rd grade years are particularly important for students to gain a strong foundation in reading as those who continue to struggle with reading are significantly less likely to achieve reading proficien ...

    SBIR Phase I 2014 Department of Education
  2. Commercializing the Effective K-3 Assessment to Instruction (A2i) Intervention to Reduce Cost and to Scale Access to the Benefit of More Students

    SBC: Learning Ovations, Inc.            Topic: N/A

    Purpose: Students who fail to achieve proficient levels of literacy are at increased risk for grade retention, referral to special education, and dropping out of high school. The kindergarten through 3rd grade years are particularly important for students to gain a strong foundation in reading as those who continue to struggle with reading are significantly less likely to achieve reading proficien ...

    SBIR Phase II 2014 Department of Education
  3. Rapid Point-of-Care Tests for Cytomegalovirus (CMV)

    SBC: Base Pair Biotechnologies, Inc.            Topic: N/A

    The human cytomegalovirus (CMV) is one of the most common intrauterine transmitted viral agents, leading to congenital CMV infection in three to ten newborns per thousand. Depending on the preexisting status of the mother, this infection leads to more or less severe symptoms and in about 2-6% the infected children die as a consequence of the infection. Beside this, sequelae occur in a number of ...

    SBIR Phase I 2014 Department of Health and Human Services
  4. Aptamers to Detect Fungi in Formalin-Fixed Sections

    SBC: Operational Techologies Corporation            Topic: N/A

    Development of novel antifungal drugs is spurring interest in the detection of pathogenic fungi in archival formalin-fixed tissues. While in situ hybridization and PCR-based methods for fungal detection in tissues exist. formaldehyde adducts on fungal DNA complicate or invalidate such detection methods. Operational Technologies Corporation (OpTech) has been developing DNA aptamers against a broad ...

    SBIR Phase I 2014 Department of Health and Human Services
  5. Rapid Detection of Endemic Fungal Infections in the U.S.

    SBC: NANOSHELL COMPANY, LLC            Topic: N/A

    Lectin recognition of fungal cell wall polysaccharides will be used to develop a rapid screening chip technology for the detection endemic fungal infection in blood. Fungal infections are life threatening to immune-compromised and immuno-suppressed patients (i.e. premature and malnourished infants, AIDS and cancer patients. seniors, and organ donation recipients). In addition to routine screenin ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. Screening for Alcohol-Related Liver Disease Using Breath Signatures by DMS

    SBC: Applied Nanotech, Inc.            Topic: NIAAA

    DESCRIPTION (provided by applicant): Alcohol abuse is rampant in the U.S., estimates run as high as 1 in 20 adults, and cost tens of billions of dollars in treatment and economic loss. One especially intransigent problem has been alcohol-induced organ disease such as alcoholic hepatitis and cirrhosis. These diseases can currently be diagnosed, but this requires invasive procedures such as liver bi ...

    SBIR Phase I 2014 Department of Health and Human Services
  7. A rapid, accurate, and easy-to-use diagnostic assay for STIs

    SBC: AI BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The aim of this application is to develop a rapid, easy-to-use, and inexpensive multi-sample diagnostic system to identify sexually transmitted infection (STI) pathogens, such as Chlamydia trachomatis (CT) and Neisseriagonorrhoeae (NG) in non-traditional healthcare settings. According to the CDC, chlamydia and gonorrhea, caused by C. trachomatis and N. gonorrho ...

    SBIR Phase I 2014 Department of Health and Human Services
  8. A Sensitive and Serotype-Specific Dengue Diagnostic Test for Low-Resource Setting

    SBC: AI BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Dengue is transmitted mainly by the Aedes aegypti mosquitoes which inhabit the tropics, making Dengue endemic to these areas. It is caused by four genetically and serologically related viruses, termed DENV1, DENV2, DENV3, and DENV4. Dengue infection is a leading cause of illness and death in the tropics and subtropics, including Puerto Rico and the U.S. Virgin ...

    SBIR Phase I 2014 Department of Health and Human Services
  9. Enhanced Efficacy Photodynamic Disinfection

    SBC: Lynntech Inc.            Topic: NIAID

    PROJECT SUMMARY This proposal is in response to the NIAID Advanced Technology SBIR (PA-10-123) Funding Opportunity. This Phase I feasibility study is an advanced technology project with a clearly identified product that will result in a clinically relevanttopical AM treatment modality. The award period and amount requested are guided by project needs and are in compliance with the issued guideline ...

    SBIR Phase I 2014 Department of Health and Human Services
  10. A Quantum Similarity Approach for the Discovery of Anti-Trypanosome Drug Leads

    SBC: GRADIENT BIOMODELING, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): Human African trypanosomiasis (HAT) is an infectious disease with a large global health burden occurring primarily in Central and Eastern Africa. HAT is 100% fatal if untreated and the current drug therapies suffer frompoor safety profiles, difficult treatment regimens, limited effectiveness, and high costs. Furthermore, drugs that cross the blood brain barrier ...

    SBIR Phase I 2014 Department of Health and Human Services
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