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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Pedestrian Auto Enforcement Program (PAEP)

    SBC: Polaris Sensor Technologies, Inc.            Topic: 122FH3

    The Pedestrian Automated System for Enforcement and Safety is a novel video and radar based system that is able to detect and track vehicles and pedestrians, and to determine when violations of pedestrian right of way have occurred. By using multiple sensor modalities the system provides a robust tracking solution. The use of radar provides long standoff detection and tracking of vehicles with hig ...

    SBIR Phase II 2014 Department of Transportation
  2. Improve Competitiveness of Specialty Crop Production through a New Product Quality Verification Method

    SBC: SMART VISION WORKS, LLC            Topic: 813

    Agricultural sorting and grading is most commonly preformed primarily through the use of human resources. Farm workers sort crops by hand through visual inspection. This process is expensive and highly subjective. In addition the labor force is susceptible to human error which can impact the quality of the resulting data. The outcome of this project will be to increase efficiencies in the grading ...

    SBIR Phase I 2014 Department of Agriculture
  3. Commercializing the Effective K-3 Assessment to Instruction (A2i) Intervention to Reduce Cost and to Scale Access to the Benefit of More Students

    SBC: LEARNING OVATIONS, INC.            Topic: N/A

    Purpose: Students who fail to achieve proficient levels of literacy are at increased risk for grade retention, referral to special education, and dropping out of high school. The kindergarten through 3rd grade years are particularly important for students to gain a strong foundation in reading as those who continue to struggle with reading are significantly less likely to achieve reading proficien ...

    SBIR Phase I 2014 Department of Education
  4. Commercializing the Effective K-3 Assessment to Instruction (A2i) Intervention to Reduce Cost and to Scale Access to the Benefit of More Students

    SBC: LEARNING OVATIONS, INC.            Topic: N/A

    Purpose: Students who fail to achieve proficient levels of literacy are at increased risk for grade retention, referral to special education, and dropping out of high school. The kindergarten through 3rd grade years are particularly important for students to gain a strong foundation in reading as those who continue to struggle with reading are significantly less likely to achieve reading proficien ...

    SBIR Phase II 2014 Department of Education
  5. Rapid Detection of Endemic Fungal Infections in the U.S.

    SBC: NANOSHELL COMPANY, LLC            Topic: N/A

    Lectin recognition of fungal cell wall polysaccharides will be used to develop a rapid screening chip technology for the detection endemic fungal infection in blood. Fungal infections are life threatening to immune-compromised and immuno-suppressed patients (i.e. premature and malnourished infants, AIDS and cancer patients. seniors, and organ donation recipients). In addition to routine screenin ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. A Quantum Similarity Approach for the Discovery of Anti-Trypanosome Drug Leads

    SBC: GRADIENT BIOMODELING, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): Human African trypanosomiasis (HAT) is an infectious disease with a large global health burden occurring primarily in Central and Eastern Africa. HAT is 100% fatal if untreated and the current drug therapies suffer frompoor safety profiles, difficult treatment regimens, limited effectiveness, and high costs. Furthermore, drugs that cross the blood brain barrier ...

    SBIR Phase I 2014 Department of Health and Human Services
  7. Endotoxin Neutralization as a Biomonitor for HIV Disease Progression

    SBC: BIODTECH, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Endotoxin neutralization in human plasma is an excellent indicator of chronic immune activation, which is the most accurate predictor of mortality in HIV. Recently we developed an assay using endotoxin neutralization asan indicator of bacterial translocation. This assay is accurate in discriminating control patients from those with inflammatory bowel disease in ...

    SBIR Phase I 2014 Department of Health and Human Services
  8. Multiplexed Ovarian Cancer Microfluidic Tissue Microarray

    SBC: Carterra, Inc.            Topic: NCI

    Project Summary We propose an instrument system for automated, multiplexed cell- and tissue-based experiments (i.e. tissue microarrays) called the Microfluidic Flow Cell Array (MFCA). The MFCA consists of a microfluidic flow cell array integrated with an inverted fluorescent microscope, allowing the observation of 48 flow chambers simultaneously or an individual chamber at higher magnification. Th ...

    SBIR Phase I 2014 Department of Health and Human Services
  9. The Development of Novel Inhibitors of BCL2 Gene Expression as Anticancer Therape

    SBC: TETRAGENE, LLC            Topic: NCI

    Project Summary Evasion of apoptosis is a hallmark of cancer and is associated with oncogenesis, tumor maintenance, and resistance to conventional chemotherapy. BCL-2 was the first identified anti-apoptotic factor and is a member of the BCL-2 family of proteins that cooperate in the regulation of programmed cell death. BCL-2 plays a dominant role in the survival of multiple lymphoid malignancies a ...

    SBIR Phase I 2014 Department of Health and Human Services
  10. New High Throughput Anti-Tumor Drug Screening System

    SBC: Vivo Biosciences Inc            Topic: NCI

    DESCRIPTION (provided by applicant): This SBIR project is focused to develop, validate and commercialize an advanced high-throughput anti- tumor drug screening platform (HTS) which employs a new 3D HuBioGEM assay technology. Preclinical drug screening is commonly performed using biochemical and cell-based assay systems. In recent years, more relevant 3D spheroid models have been developed using mi ...

    SBIR Phase I 2014 Department of Health and Human Services

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