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DESCRIPTION provided by applicant A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellariumandquot for treatment of glial cell based cancers Successful completion of this project will confirm therapeutic effect and pre clinical safety of the vaccine in preparation for first in human studies Upon demonstration of ...

The primary goal of the proposed STARA innovation is to develop and demonstrate a high altitude precision guided parafoil system that will enable NASA to control the final landing point of the sounding rocket payload, thus reducing system offset, recovery time, and recovery cost. Current recovery methods utilize unguided parachutes, which are susceptible to large uncertainties in recovery location ...

This Small Business Innovation Research (SBIR) Phase II project will develop and produce a robust, hand-held, video-rate three-dimensional surface metrology system with vertical and lateral resolution of several micrometers, in order to bridge a critical existing metrology gap for precision-machined surfaces. Many modern manufactured parts, such as turbine blades, drive shafts, orthopedics, and va ...

ABSTRACT:A system is proposed to access, collate and process imagery from multiple small satellite constellations. The imagery is fused and registered to a common reference so that exploitation algorithms, such as change detection and event monitoring, are reported with accurate geographic coordinates. The system, called SatTel, is implemented as open source software that is designed to run on the ...

Unmanned automated convoys provide an efficient means for transporting the cargo of many vehicles across the same terrain to reach a desired location. As more vehicles are added, the efficiency of the convoy can increase; however, if each successive vehicle uses the previous vehicle for path following, the convoy accuracy will gradually degrade. In order to improve the path following of successive ...

Additive manufacturing lacks efficient, composable physics-based computational frameworks to predict quality and performance for arbitrary geometry, orientation, location and process parameter combinations. A new set of composable computational tools capable of accurately predicting the geometrical accuracy, residual stress and microstructure of the parts made using metal based AM has been develop ...

Abstract Vaccines are fundamental in preventing debilitating illnesses and saving millions of lives each year But despite these vaccine oriented victories infectious diseases are still the second leading cause of death as well as the leading cause of disability adjusted life years worldwide About six million deaths were attributed to AIDS malaria and tuberculosis in regions where no vaccine ...

DESCRIPTION provided by applicant The human genome encodes protein kinases that catalyze the phosphorylation of client proteins Signal transduction mediated by protein impacts virtually all aspects of cellular physiology from the coordination of the cell cycle and cll division to apoptosis Not surprisingly the deregulation of kinases is implicated in many diseases including diabetes in ...

The broader impact/commercial potential of this project lies in its ability to implement multiple-input multiple-output (MIMO) detectors of any size. This, in turn, impacts the broad needs of wireless communications industry that is always in search of more efficient use of the scarce spectral resources. Since its invention 15 years ago, MIMO has been included in all wireless standards, e.g. WiFi, ...

DESCRIPTION provided by applicant THE MEMORY CARE NAVIGATOR A PROACTIVE GUIDE Memory loss is an increasing problem as our population ages causing a tremendous personal and societal toll in disability and cost Alzheimerandapos s disease AD the most common cause of dementia is the illness elderly Americans most fear and the only major illness with an increasing mortality rate Despite subs ...