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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Calcaftor, a CFTR stabilizer for Cystic Fibrosis treatment

    SBC: Calista Therapeutics, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

    SBIR Phase I 2014 Department of Health and Human Services
  2. Inter-alpha-inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, LLC            Topic: NINDS

    DESCRIPTION (provided by applicant): Neonatal hypoxia-ischemia (HI) remains a major cause of acute perinatal brain injury, leading ultimately to neurologic dysfunction manifesting as cerebral palsy, mental retardation, and epilepsy. Cerebral oxygen deprivation and/or reduced blood flow due to umbilical cord occlusion, prolonged labor, and/or intracranial hemorrhage produce an inflammatory respons ...

    SBIR Phase I 2014 Department of Health and Human Services
  3. IGF::OT::IGF High-Impact Substance Abuse Prevention Technologies. SBIR Phase I. Period of Performance 7/16/2014-1/15/2015

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    The overarching objective of this project is to develop an innovative technological tool that will facilitate the implementation of an evidence-based substance abuse prevention program and related health behavior risk programs among military personnel. PUBLIC HEALTH RELEVANCE

    SBIR Phase I 2014 Department of Health and Human Services
  4. Integration of Complex Geometry, 3D Woven Preforms via Innovative Stitching Technique

    SBC: T.E.A.M., INC.            Topic: H701

    Thick, 3D woven carbon/phenolic composites offer potential improvement over legacy thermal protection systems (TPS) for re-entry vehicle heat shield applications. However due to the scale and complexity of typical re-entry vehicle structures, it is likely that multiple 3D woven panels would need to laid up to create the overall heat shield, creating a potential weak spots at the panel joints. ...

    SBIR Phase I 2014 National Aeronautics and Space Administration
  5. Advancing High Energy Lithium-Sulfur Batteries

    SBC: Yardney Technical Products, Inc.            Topic: Z102

    Lithium-Ion batteries have been a main source of energy for many aerospace applications over the past decade. Future space missions are facing a number of challenging requirements, including significant increase in specific energy, approaching 500 Wh/kg, and energy density of 700 Wh/l at cell level. Compared to state-of-the-art technology today, a reduction in mass and volume are necessary, along ...

    SBIR Phase I 2014 National Aeronautics and Space Administration
  6. Sensitive and Shape-Specific Molecular Identification

    SBC: RYON TECHNOLOGIES, INC            Topic: A11aT017

    The ability to rapidly detect, identify and monitor chemical agents remains a challenge of significant importance to the Armed Forces. Existing chemical sensing techniques have shortcomings that inhibit widespread implementation. To address this situation, Ryon Technologies is developing a portable instrument that is based on Rydberg Fingerprint Spectroscopy (RFS) in combination with mass spectrom ...

    STTR Phase II 2014 Department of DefenseArmy
  7. Safe, Large-Format Lithium Ion Batteries for Aircraft

    SBC: Yardney Technical Products, Inc.            Topic: AF141071

    YTP will develop technology that provides a high performance, modular Li-ion battery with: redundant safety features, safer thin, metal case cell designs; fin/micro-channel thermal control system; and an evaporating fluid system that rapidly quenches failing cells to prevent thermal runaway and fratricide. The end goal of the proposal is making a lighter, longer lasting, less expensive, safer JSF ...

    SBIR Phase I 2014 Department of DefenseAir Force
  8. Low-Profile, Broadband, Shear-Mode SONAR Transducer for Deep Submergence Applications

    SBC: Btech Acoustics, LLC            Topic: N141066

    BTech proposes the design and development of a low-profile, broadband, shear-mode piezocrystal acoustic transducer for deep submergence applications. The Phase I effort considers evaluation of design variants of shear mode transducers with increased pressure operation/tolerance and tradeoffs associated with the same. Design feasibility is supported with calculations of expected performance and whe ...

    SBIR Phase I 2014 Department of DefenseNavy
  9. Innovative Acoustic Velocity Sensors

    SBC: Btech Acoustics, LLC            Topic: N141026

    BTech proposes the design and development of low-profile, innovative acoustic velocity sensors for measuring acoustic motion of sound waves in marine applications. Methods include increasing voltage sensitivity by novel connections, considerations of co-located preamplifiers, multiple plates, improved materials and more. An improved acoustic motion accelerometer sensor for hull arrays is proposed ...

    SBIR Phase I 2014 Department of Defense
  10. Innovative Designs for Reliable Electro-Explosive Ordnance Devices

    SBC: SYSTEMS ENGINEERING ASSOCIATES CORPORATION            Topic: MDA12031

    Missiles, use electro-explosive devices (EEDs) to perform mulitple functions during operation. This effort seeks ways to improve on the EED"s reliability and lower the failure or inadvertent activation rate of these devices. During Phase I, SEA CORP investigated replacing EEDs with commercial off the shelf (COTS) automotive airbag inflators to perform the required pneumatic functions of variou ...

    SBIR Phase II 2014 Department of DefenseMissile Defense Agency
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