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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Goal Guide: A Web-Based Application for Self-Management of Goal Tracking

    SBC: Assistech Systems LLC            Topic: N/A

    This is a Phase II project to develop and evaluate the effectiveness of a responsively designed web application, Goal Guide, that enables individuals with intellectual disabilities and autism to effectively manage self-defined goals for everyday living across personal, educational, and vocational life domains. Users will be able to easily enter goals, work with data for each goal, engage with info ...

    SBIR Phase II 2014 Department of Education
  2. Novel Single Well Avidity EIA to Determine Recency of HIV-1 Infections

    SBC: SEDIA BIOSCIENCES CORPORATION            Topic: NIAID

    DESCRIPTION (provided by applicant): The objectives of this project are to develop a commercial single well HIV-1 Limiting Antigen Avidity EIA, developed in Phase I as a research tool, and establish its suitability for identifying recent HIV-1 infections on both a population an on an individual clinical basis as an aid to early intervention in acute infections. Such methods are needed for accurate ...

    SBIR Phase II 2014 Department of Health and Human Services
  3. Therapeutic Thrombin Analogs

    SBC: Aronora, Inc            Topic: NHLBI

    DESCRIPTION (provided by applicant): Project Summary/Abstract Treatment of acute ischemic stroke (AIS) with the thrombolytic/antithrombotic agent tissue plasminogen activator (tPA, Activase(R)) is limited due to the potential for severe hemorrhagic side effects. The first symptoms of acute ischemia to tPA treatment ( time to needle ) can span hours, even in developed urban areas, since an establis ...

    SBIR Phase II 2014 Department of Health and Human Services
  4. IGF::OT::IGF Novel siRNA-nanoparticle Platform for Treating Drug-Resistant HER2 Positive Breast Cancer

    SBC: PDX PHARMACEUTICALS, LLC            Topic: NCI

    Over one million women worldwide are diagnosed with breast cancer each year. Roughly 20% of all breast cancers overexpress the human epidennal growth receptor 2 (HER2-positive subtype). HER2-targeted therapies, including Herceptin and lapatinib, account for 55% of the breast cancer therapy market in 2011 (or $5 billion annually). Response to HER2-targeted therapies typically average about one year ...

    SBIR Phase II 2014 Department of Health and Human Services
  5. Chitosan Endoluminal Hemostatic Dressing

    SBC: HemCon Medical Technologies Inc            Topic: 400

    DESCRIPTION provided by applicant Perioperative hemorrhage remains the major complication of transurethral and open prostatic surgical procedures Significant blood loss from these procedures causes delayed healing and longer hospitalization which significantly increases the cost of patient care Moreover prolonged urethral catheterization due to significant post operative hematuria is one of ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Preclinical development of novel small molecule malaria drugs that overcome drug

    SBC: DESIGNMEDIX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The worldwide health problem created by malaria has been made more difficult by the spread of drug resistant parasites We have developed an orally available and inexpensive class of novel drugs that act against both chloroquine resistant and chloroquine sensitive malaria This project carries on preclinical development of a drug candidate that has been select ...

    STTR Phase II 2014 Department of Health and Human Services
  7. A human cytomegalovirus-based immunotherapy for HIV-1

    SBC: TOMEGAVAX, INC.            Topic: NIAID

    DESCRIPTION The ultimate goal of this project is to develop an immunotherapy for human immunodeficiency virus HIV based on a spread deficient cytomegalovirus CMV derived vaccine expressing andquot tailoredandquot antigens designed for maximal coverage of clade B epitopes In non human primate models rhesus CMV vectored vaccines demonstrated unprecedented protection against highly virulent ...

    SBIR Phase II 2014 Department of Health and Human Services
  8. Fathering Through Change: Online Parent Training for Divorced Fathers (FTC)

    SBC: IRIS MEDIA INC            Topic: NICHD

    DESCRIPTION provided by applicant The goal of this Phase II project Fathering Through Change FTC Online Parent Training for Divorced Fathers is to provide a severely underserved population divorced fathers with the skills necessary to be effective parents to their children and co parents with their former spouses To provide this training FTC will adapt the Parent Management Training ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Therapeutic Thrombin Analogs

    SBC: Aronora, Inc            Topic: NHLBI

    DESCRIPTION provided by applicant Project Summary Abstract Treatment of acute ischemic stroke AIS with the thrombolytic antithrombotic agent tissue plasminogen activator tPA Activase is limited due to the potential for severe hemorrhagic side effects The first symptoms of acute ischemia to tPA treatment andquot time to needleandquot can span hours even in developed urban areas since ...

    SBIR Phase II 2014 Department of Health and Human Services
  10. Padres Preparados: An Evidence-Based Parenting Intervention for Latino Families

    SBC: IRIS MEDIA INC            Topic: NICHD

    DESCRIPTION provided by applicant Latino youth currently comprise more than one fifth of the US youth population Mather andamp Foxen yet this sizeable group of the nationandapos s future adults lags alarmingly behind non Latino youth in academic achievement The proposed program Padres Preparados A Cultural Adaptation of an Evidence Based Parenting Intervention for Latino Families ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health

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