You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Goal Guide: A Web-Based Application for Self-Management of Goal Tracking

    SBC: Assistech Systems LLC            Topic: N/A

    This is a Phase II project to develop and evaluate the effectiveness of a responsively designed web application, Goal Guide, that enables individuals with intellectual disabilities and autism to effectively manage self-defined goals for everyday living across personal, educational, and vocational life domains. Users will be able to easily enter goals, work with data for each goal, engage with info ...

    SBIR Phase II 2014 Department of Education
  2. Physiologically Compatible Hemodialysis through Advanced Dialysate Regeneration

    SBC: Chemica Technologies, Inc            Topic: N/A

    The uremic syndrome is a disabling condition attributed to the progressive retention of solutes that would normally be excreted by the kidneys and which interact negatively with physiological systems/functions. These are broadly defined as uremic toxins. Hemodialysis treatment is prescribed for the majority of individuals in the final stages of renal failure. However, better dialysis options (leng ...

    SBIR Phase I 2014 Department of Education
  3. Web-Based Training in Alcohol SBIRT for Youth Aged 9-18

    SBC: Oregon Center For Applied Science, Inc            Topic: NIAAA

    DESCRIPTION (provided by applicant): Underage alcohol consumption is a public health concern with numerous negative sequelae, including adoption of other risky behaviors (smoking, other drug use, at-risk sexual behavior, drinking and driving), increased rates of depression or suicidal ideation, poor academic achievement, and behavioral problems (delinquency, violence, crime). Adolescents who drink ...

    SBIR Phase I 2014 Department of Health and Human Services
  4. Mobile Intervention to Enhance Physical Activity in the Chronically Ill

    SBC: Oregon Center For Applied Science, Inc            Topic: NIA

    PROJECT SUMMARY This project aims to fill the urgent need for a safe and engaging intervention that promotes physical activity in a population of patients with chronic diseases (e.g., diabetes, asthma, osteoarthritis, and chronic heart failure). Compelling evidence suggests that physical activity is an effective therapeutic intervention for numerous chronic diseases. However, in spite of the wide ...

    SBIR Phase I 2014 Department of Health and Human Services
  5. Microfluidic screening devices for health-span extending drugs

    SBC: NEMAMETRIX, INC            Topic: NIA

    Aging, the progressive degeneration of body and mind, is a universal problem marked by a decline in tissue organization and function, and an increase in the likelihood of death. Progress in understanding the cellular and molecular basis of aging is rapidlyaccelerating, following the discovery that several well-known model organisms age in many of the same ways as humans. In addition to their contr ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. Destroying the HIV-1 provirus by utilizing components of the CRISPR/Cas system

    SBC: CELDARA MEDICAL, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): The goal of this project is to develop a plasmid-based therapy that will destroy the integrated HIV-1 DNA (HIV- 1 provirus) in infected cells. Current HIV-1 anti-retroviral therapy (ARV) consists of a cocktail of drugsthat blocks viral binding and replication, but does not destroy the HIV-1 provirus. In addition, ARV does not impact the large reservoir of laten ...

    SBIR Phase I 2014 Department of Health and Human Services
  7. Development and Commercialization of an Innovative Rapid HIV-1 Incidence Assay

    SBC: SEDIA BIOSCIENCES CORPORATION            Topic: NIAID

    DESCRIPTION (provided by applicant): The objective of this project is to develop a commercially viable point of care Rapid HIV-1 Incidence Assay and establish its suitability for determination of recency of HIV-1 infection in whole blood, plasma, serum specimens for epidemiological, research and surveillance purposes. It is further intended to determine the feasibility of the application of the as ...

    SBIR Phase I 2014 Department of Health and Human Services
  8. Synergy between MAG-1 and Cyclophosphamide for Treatment of Recurrent SCLC

    SBC: Woomera Therapeutics, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): There is currently no effective treatment for recurrent small-cell lung cancer (rSCLC). The objective of this project is to utilize a monoclonal antibody, MAG-1, to develop new, rational, and successful treatment of rSCLC. The hypothesis being tested is that a cancer -specific provasopressin antigen, called GRSA, present at the surface of these tumors will prov ...

    SBIR Phase I 2014 Department of Health and Human Services
  9. An effector memory T cell-based therapeutic cervical cancer vaccine

    SBC: TOMEGAVAX, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): The longterm goal of this project is to utilize cytomegalovirus (CMV) vectors carrying oncogenes of high risk human papillomaviruses (HPV) as novel therapeutic vaccines against cervical cancer. Although recently launched prophylactic vaccines protect against HPV infection, these VLP-based vaccines have not demonstrated significant benefit for individuals who a ...

    SBIR Phase I 2014 Department of Health and Human Services
  10. Dampening CAR therapy-induced cytokine storm with anti-GM-CSF antibodies

    SBC: CELDARA MEDICAL, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): The long-term aim of this project is to reduce or eliminate the serious adverse events associated with cellular immunotherapy used to treat cancer. The current impressive efficacy of chimeric antigen receptor (CAR) T cell therapies is often accompanied by a well-known toxicity stemming from the large release of cytokines from activated immune cells, known as a ...

    SBIR Phase I 2014 Department of Health and Human Services
US Flag An Official Website of the United States Government