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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 4695 results
  1. SBIR Phase II:Resilience for Waterfront Infrastructure

    SBC: NATRX INC            Topic: ET

    The broader/commercial impact of this Small Business Innovation Research (SBIR) Phase II project is to drive restoration and preservation of coastal wetlands by unlocking their ecosystem value. Many coastal communities are underserved and do not have resources to adapt to increasing risks from erosion, storms, and sea level rise. Enhanced coastal resilience and restoration promotes biodiversity, w ...

    SBIR Phase II 2023 National Science Foundation
  2. SBIR Phase II:A Digital Platform That Engages Elementary Aged Girls in STEM Through Personalized Informal Learning

    SBC: SMART GIRLS HQ LLC            Topic: LC

    The broader/commercial impact of this Small Business Innovation Research (SBIR) Phase II project is an increase in the representation of women in Science, Technology, Engineering, and Math (STEM) employment areas, enabling the US to meet the increasing demand for STEM workers and maintain competitiveness in the global innovation community. The factors contributing to the underrepresentation of gir ...

    SBIR Phase II 2023 National Science Foundation
  3. Addressing bone marrow lesions that compromise osteochondral tissue repair

    SBC: Cytex Therapeutics, Inc.            Topic: NIAMS

    ABSTRACT Degenerative joint diseases such as osteoarthritis (OA) remain the source of significant pain and disability, affecting over 30 million adults with an annual US economic burden of more than $486 billion. Joint replacement is a well-established procedure, but its finite life span makes this treatment unacceptable for younger (under 65) or more active individuals. For this growing patient p ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. A metabolomics-based laboratory developed test to improve the diagnostic precision of Polycystic Ovary Syndrome

    SBC: METABOLON, INC.            Topic: NICHD

    Abstract Polycystic ovary syndrome (PCOS) is a complex, multifactorial endocrine disorder characterized by hyperandrogenism, chronic anovulation, and polycystic ovaries. It is currently diagnosed by the Rotterdam criteria, which categorizes the presentation of these basic symptomologies into four main phenotypes labeled A, B, C, and D. While these phenotypes can define disease and inform clinical ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Inter-alpha Inhibitors in Experimental Necrotizing Enterocolitis

    SBC: PROTHERA BIOLOGICS, INC.            Topic: NICHD

    Necrotizing enterocolitis (NEC) is a devastating acute inflammatory condition of the gastrointestinal tract resulting in intestinal necrosis, systemic sepsis and multi-system organ failure found mostly in infants born prematurely. Despite modern medical advances in the past decade, the etiology remains elusive and morbidity and mortality are still unacceptably high. It has been concluded that the ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Micro-Organospheres Drug Screen to Lead Care (MODEL): a Precision Oncology Platform to Guide Breast Cancer Therapy

    SBC: XILIS INC            Topic: 102

    PROJECT SUMMARY/ABSTRACT The goal of precision oncology is to match cancer patients with medicines based on the specific biology of their tumor. Crucially, the current precision oncology paradigm – which is largely based on tumor genomic profiling – doesn’t work for the majority of patients. Since every patient’s tumor is uniquely complex, a potential solution to this “precision” probl ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Multiomic genomic mapping with long read sequencing

    SBC: Epicypher, Inc.            Topic: 400

    PROJECT SUMMARYGenomic mapping of histone post-translational modifications (PTMs), chromatin-associated proteins (CAPs), and DNA methylation (DNAme) is a powerful approach for biomedical research and drug development. Current genomics assays (e.g. ChIP-seq, CUTandRUN) rely on second generation short-read sequencing (SRS), wherein short reads (lt500bp) limit the ability to a) analyze concordance of ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Culture-free microbial enrichment for diagnosis and characterization of anti-microbial resistance

    SBC: Triangle Biotechnology, Inc.            Topic: CDC

    Abstract Timely identification of infectious agents enables targeted antibiotic administration and better health outcomes for patients. However, current methodologies take days to months, leading to the administration of broad- spectrum antibiotics when they may not be appropriate or effective. Drastic cost reductions of DNA sequencing technologies have led to increased demand for such workflows t ...

    SBIR Phase I 2023 Department of Health and Human ServicesCenters for Disease Control and Prevention
  9. SBIR Phase I:Development of an enzymatic method to produce compounds found in human milk at commercial scale

    SBC: MAMMAE BIOSCIENCES, INC.            Topic: BT

    The broader/commercial impact of this Small Business Innovation Research (SBIR) Phase I project is to assess an affordable enzymatic method for producing marketable natural compounds usually found in human milk. Once this strategy is validated, it could be implemented by domestic and industrial users. The technology is capable of transforming the lactose in milk to highly desirable compounds. Thes ...

    SBIR Phase I 2023 National Science Foundation
  10. Improving parent-adolescent communication about sexual and reproductive health

    SBC: Teen Health Research, Inc.            Topic: NICHD

    PROJECT SUMMARY Early adolescence, between the ages of 10-13, is a critical time for sexuality development. It is a period when most young people enter puberty and have new questions about bodies, relationships, and sexual activity. However, the majority of US adolescents enter this early adolescent period without access to the kind of inclusive, comprehensive sex education that could help them de ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
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