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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 5273 results
  1. Plasma-assisted atomic layer deposition of alumina and Parylene-C bi-layer encaps

    SBC: BLACKROCK MICROSYSTEMS            Topic: NIBIB

    DESCRIPTION provided by applicant A range of neurological diseases are now being researched or treated using fully implantable electronic systems to either record or modulate brain activity in humans These implants are currently being protected using polymer coatings that envelop the implant and help keep body fluids away from the sensitive electronics Brain implants with complex three dimens ...

    SBIR Phase I 2014 Department of Health and Human Services
  2. Targeting B-cell lymphoma with Leukothera-phase II

    SBC: ACTINOBAC BIOMED, INC.            Topic: NCI

    DESCRIPTION provided by applicant B cell lymphoma is cancer of B lymphocytes and accounts for more than deaths in the U S each year While many patients respond to currently available therapy there is a high rate of cancer relapse and inability for the patients o tolerate chemotherapy Thus there is a significant need to make available to these patients newer therapies that are more e ...

    STTR Phase II 2014 Department of Health and Human Services
  3. Transcutaneous Energy Transmission System for Fully Implantable VADs

    SBC: Minnetronix Medical, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant Mechanical circulatory support devices have become increasingly common in the treatment of end stage heart failure primarily in the form of the Left Ventricular Assist Device LVAD Survival and quality of life have improved steadily due to the transition from larger pulsatile devices to small continuous flow devices as well as improved patient selection an ...

    SBIR Phase II 2014 Department of Health and Human Services
  4. Remote-Access Data Enclave for HRS/PSID Analysis

    SBC: Acumen, LLC            Topic: NIA

    DESCRIPTION provided by applicant To enhance the utility of federally funded surveys Acumen through a project entitled the Medicare Medicaid Research Information Center MedRIC has pursued adding individual linked administrative data from the Centers for Medicare andamp Medicaid Services CMS to supplement information in these survey data Two prominent surveys are the Health and Retiremen ...

    SBIR Phase II 2014 Department of Health and Human Services
  5. A Novel Approach to Assessing Cognitive State During Real-World Tasks

    SBC: ADVANCED BRAIN MONITORING, INC.            Topic: 105

    DESCRIPTION provided by applicant In Phase our team was able to enhance the ABM B Alert system for use in on the road evaluations by reducing the overall profile of the hardware system introducing real time commenting for marking events in real world activities and assessing and confirming current artifact rejection algorithms for sufficiency in real world environments In addition the ...

    STTR Phase II 2014 Department of Health and Human Services
  6. Development of novel agents for the treatment of renal fibrosis adminstrative supplement

    SBC: Epigen Biosciences, Inc.            Topic: 300

    DESCRIPTION provided by applicant The ultimate goal of our project is to develop novel therapeutics effective in chronic kidney diseases that normally develop fibrosis lead to end stage renal disease and require renal replacement therapy This SBIR phase application builds on the results obtained in phase where novel and selective small molecule antagonists were discovered that prevent the ...

    SBIR Phase II 2014 Department of Health and Human Services
  7. Development of P2X3 Ion Channel MAbs for the Treatment of Pain

    SBC: INTEGRAL MOLECULAR, INC            Topic: 100

    DESCRIPTION provided by applicant Acute and chronic pain resulting from injury surgery or disease afflicts andgt million Americans each year having a severe impact on mood mental health and quality of life and costing the U S approximately $ billion in economic costs annually For many patients treatment options provide inadequate relief because of the shortcomings of available th ...

    SBIR Phase II 2014 Department of Health and Human Services
  8. An Early-Phase Clinical Trial Evaluating ABC294640 in Patients with Refractory/Re

    SBC: Apogee Biotechnology Corporation            Topic: 102

    DESCRIPTION provided by applicant Diffuse large B cell lymphoma DLBCL represents one of the most common variants of Non Hodgkinandapos s lymphoma NHL and oncogenic herpesviruses EBV and KSHV are the etiologic agents for the majority of these tumors in patients over or those infected with the human immunodeficiency virus HIV Despite modest improvements in outcomes for patients rece ...

    STTR Phase II 2014 Department of Health and Human Services
  9. Vault-CCL21 Nanocapsule for Lung Cancer

    SBC: PROTEIN SCIENCES CORPORATION            Topic: NCI

    DESCRIPTION provided by applicant Lung cancer is the leading cause of cancer death in the United States and is responsible for more deaths each year than breast prostate colon hepatic renal and skin cancers combined Viewed in economic terms in the United States the value of life lost from lung cancer deaths in the year was more than $ billion which is estimated to rise to more t ...

    SBIR Phase II 2014 Department of Health and Human Services
  10. Peptide-coated skin substitutes for the treatment of burn injuries and wounds

    SBC: AFFINERGY, LLC            Topic: 300

    DESCRIPTION provided by applicant Burn injuries and chronic wounds present a significant burden to patients and the US healthcare system Each year in the US there are burns that require medical treatment and burn patients that require hospitalization The mortality rate associated with severe burns can be as high as with of patient deaths arising from infection In add ...

    SBIR Phase II 2014 Department of Health and Human Services

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