Award Data

DESCRIPTION (provided by applicant): It is widely accepted that the existing clinical paradigm of one treatment fits all is a major factor in the lack of progress in the effective treatment of a highly heterogeneous diseases. We propose a new innovative cl inical paradigm that optimizes brain cancer therapy using patient-specific markers of therapeutic response. Our long-term objective is to impro ...

We propose new concepts for developing components for high performance space based Lidar systems. While it is generally recognized that photonic crystal fiber technology can extend the performance range of fiber laser based sources these fibers are considered by many to be incompatible with complementary component technology such as fused couplers and pump combiners. Integration of these fibers i ...

Tactical laser sources delivering high-peak-power (from multi-MW to TW) in agile optical pulse trains at high pulse repetition frequency (PRF) in the eye-safe wavelength region are of interest for several military applications including proactive infrared countermeasures (PIRCM), non-lethal munitions, and remote sensing of battlefield threats. To meet the needs for future tactical lasers, Aculigh ...

Electron accelerators allow researchers to advance energy and luminosity frontiers and expand our knowledge of nuclear physics and basic materials science. To achieve the best performance, specialized lasers are used to produce electrons for these accelerators. The lasers not only must be precise and reliable but also much more powerful than those that are currently available. This project will de ...

Tactical laser sources delivering high peak power (from multi-MW to TW) in agile optical pulse trains at high pulse repetition frequency (PRF) in the 3.5-4 µm wavelength region are of interest for several military applications including proactive infrared countermeasures (PIRCM), non-lethal munitions, and remote sensing of battlefield threats. To meet the needs for future tactical lasers, Aculig ...

DESCRIPTION (provided by applicant): Vestibular disorders represent a debilitating medical problem by causing balance and vision impairments that adversely affects the lives of people of all ages and backgrounds. The restoration of vestibular function by d irect stimulation of the vestibular nerve, bypassing the sensory organs, is expected to alleviate these symptoms in some patients. Currently, t ...

DESCRIPTION (provided by applicant): Iatrogenic nerve damage is one of the most adverse sequalae of tumor resection surgery in all parts of the body. Many neuromonitoring techniques have been developed to lower the incidence of damage, most notably electr ostimulation. However, the clinical potential of precise neuromonitoring remains unfulfilled, due to several key limitations intrinsic to elect ...

SBC of high-power fiber lasers uniquely links an efficient, versatile, and robust power scaling architecture to individual emitters with outstanding efficiency, diffraction-limited beam quality, and distributed thermal loading. Fiber SBC, thus provides an exceptionally promising pathway to scalable, high efficiency laser systems with high average power, superb power-to-mass ratios, and near perfec ...

DESCRIPTION (provided by applicant): A novel sulfonated polymer with unique chemically tailorable properties and processing characteristics has shown considerable promise as a thrombo- resistant surface and has been proven to be effective inhibitor against neutrophil- derived proteases. A phase 1 SBIR testing is proposed to investigate this polymer as a tailorable interface coating for blood-cont ...

Andrews Space proposes an inflatable rigidizable wing that can be stored folded or rolled up, and deployed at altitude via an inflation system, and will then cure to form a rigid wing improving the reliability and reducing the risk of an inflatable wing. It will also be much lighter and have a much smaller storage volume than a mechanically folding wing. A high altitude, long endurance aircraft c ...