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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Small Engines Designed for High Efficiency, High Power Density and Quiet Operations

    SBC: XRD, INC.            Topic: SB082010

    XRD Inc. will deliver a feasibility study and work plan to produce engines operating on heavy fuel that meets the objectives of Program Solicitation entitled “Small Engines designed for High Efficiency, High Power Density and Quiet Operations”. The goal is to have power density greater than 1 hp per pound and greater than 25% thermal efficiency while operating on available heavy fuels. This n ...

    SBIR Phase I 2009 Department of DefenseDefense Advanced Research Projects Agency
  2. Novel Inhibitors of Pim Protein Kinases

    SBC: VORTEX BIOTECHNOLOGY CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): There is a growing body of evidence that implicates the protein kinase Pim-1 as a major driver of prostate cancer progression, and perhaps response to chemotherapy. Pim-1 is overexpressed in early prostate intraepithelial neoplasia and metastatic prostate cancer, and its levels predict response to therapy. Pim-1-overexpressing mouse prostate stem cells demonstr ...

    STTR Phase I 2009 Department of Health and Human Services
  3. STTR Phase I: Ammonothermal Growth of Doped Aluminum Gallium Nitride Single Crystals for Energy Efficient Solid State Lighting and Tunable LED?s

    SBC: ADVANCED PHOTONIC CRYSTALS, LLC            Topic: MM

    This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Technology Transfer Phase I project will address the problem of a multifunctional wide band-gap aluminum gallium nitride single crystal substrate that will enable low-defect, high-performance epitaxial growth. Since much of the energy consumed in the U.S. used for traditional ligh ...

    STTR Phase I 2009 National Science Foundation
  4. SBIR Phase I: Hydrothermal Growth of Potassium Beryllium Fluoroborate (KBBF) for deep UV Nonlinear Optical Applications.

    SBC: ADVANCED PHOTONIC CRYSTALS, LLC            Topic: NM

    This Small Business Innovative Research Phase I project is to develop a commercial growth process for single crystals of KBe2BO3F2 (KBBF) using hydrothermal techniques. KBBF shows exceptional promise as a deep UV non-linear optical material (NLO). NLOs are vital for the development of solid-state lasers with wavelengths below 200 nm for use in photolithography, micromachining and spectroscopy. The ...

    SBIR Phase I 2009 National Science Foundation
  5. Acid Ceramidase, Target for Cancer

    SBC: Sphingogene, Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Acid ceramidase (AC) has been implicated as a novel target for cancer therapy because of its pivotal role in regulating interconversion of three key bioactive lipids; ceramide (Cer), sphingosine (Sph) and Sphingosine-1-Phosphate (S1P). It is well known that Cer functions predominantly as a tumor suppressor lipid and mediator of apoptosis following chemo and rad ...

    STTR Phase I 2009 Department of Health and Human Services
  6. Controlling Intracellular Ice Formation with Antifreeze Proteins

    SBC: Cell & Tissue Systems, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Long term preservation is crucial as an enabling technology for regenerative medicine products that contain living cells. However, while cryopreservation works well for most cells, some cells are more sensitive and hard to cryopreserve by freezing. Plus, the three dimensional structure and extracellular architecture of tissues is damaged by ice formation that r ...

    SBIR Phase I 2009 Department of Health and Human Services
  7. Feasibility of Unfrozen Sub-zero Storage of Mammalian Tissues with Insect Anti-Fr

    SBC: Cell & Tissue Systems, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The long term goal is the development of better, longer hypothermic storage conditions, using novel insect antifreeze proteins, for liver transplants than is currently possible in clinical practice. The use of hypothermia as the principal means to suppress metabolism in a reversible way is the foundation of most of the effective methods for tissue and organ sto ...

    SBIR Phase II 2009 Department of Health and Human Services
  8. SBIR Phase I: Low Cost, Robust Multi-Gas Sensors for Environmental Sensing Applications

    SBC: SENS4            Topic: EL

    This Small Business Innovation Research (SBIR) Phase I research project will develop a gas sensor technology that is both highly sensitive and selective, with a rapidity and accuracy not yet seen in commercially available technologies. This will develop an integrated high performance, low cost, and compact gas sensor device for environmental monitoring, with emphasis placed on the early and reliab ...

    SBIR Phase I 2009 National Science Foundation
  9. A Cryo-coil MAS 1H/13C/2H/15N Probe for Highest S/N in NMR of Solids

    SBC: DOTY SCIENTIFIC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): For over three decades, High-Resolution (HR) Nuclear Magnetic Resonance (NMR) has been a leading analytical technique for structure and function elucidation of molecules of all types, large and small, in homogeneous systems. More recently, Magic Angle Spinning (MAS) has been combined with high-field HR-NMR to extend the technique to inhomogeneous systems, such ...

    SBIR Phase I 2009 Department of Health and Human Services
  10. A Risk Reduction Process for Enhanced Mission Assurance

    SBC: ADVANCED CORE TECHNOLOGIES, LLC            Topic: MDA08021

    Advanced Core Technologies brings three advanced competencies together to support a successful research effort required to identify, foster, and deploy technologies promising reliability enhancing materials and manufacturing innovations. Self-learning search methods, sophisticated information association techniques, and stochastic forecasting enables a system capable of 5, 10, and 20 year forecas ...

    SBIR Phase I 2009 Department of DefenseMissile Defense Agency

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