Award Data

DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

The goal of this proposal is find novel combinations of approved drugs for the treatment and/or prevention of infection with filoviruses. Ebola and Marburg viruses, the only filoviruses, cause an acute hemorrhagic fever syndrome which has a high mortality rate and poses a significant bio-terrorism threat. There are currently no therapeutic agents available to treat filovirus infections and the de ...

DoD space surveillance and weapons systems require highly accurate inertial knowledge in absolute location and angular orientation. Current technologies providing these functions are not integrated into a single, light-weight, low-cost, power-efficient instrument. Applied Technology Associates (ATA) proposes to further develop its innovative and patented optical inertial reference unit technolog ...

For Airborne Inertial Rate Sensors, Applied Technology Associates (ATA) proposes to introduce a unique and enabling gyroscope technology based upon the principles of magnetohydrodynamics (MHD) that meet all requirements for ABL operation, including flight environment, extreme slew and in precision track. The Enhanced MHD Effect Rate Gyro (EMERG) has the highest potential of outperforming existin ...

As the Airborne Laser (ABL) comes closer to putting a high energy laser (HEL) on a boosting missile target, it has become obvious that a high bandwidth fast steering mirror (FSM) needs to be developed. This FSM must be capable of controlling large, 12-inch mirrors while handling the HEL power levels. Applied Technology Associates (ATA) proposes to develop for the Missile Defense Agency (MDA) revo ...

The development of a generalized moving body capability for Computational Fluid Dynamics (CFD) flow simulations of highly transient flowfields is critical to system analyses of Divert and Attitude Control Systems (DACS) for Kinetic Warheads (KWs). Testing capabilities are limited in the DACS operating regime; therefore, computational tools are essential for such analyses. The flow in the DACS its ...

This phase I SBIR proposal addresses development of a generalized benign, high throughput, low-cost silicon die thinning etch tool. Thinning of Si dies is required in many advanced 3-D packaging, rad-hard and flexible-circuit electronics. For example, using hyper-thin (~ 10-25 m) Si memory dies, a stack of 500 MCMs/inch can be formed to provide ~ 200 gigabits/cu. in. density using 64 mbits Si m ...

High energy optical components, such as beam splitters, are specified and designed to meet increasingly tight system level alignment budgets while subjected to severe environmental loads. These loads include shock and vibration loads generated by a number of sources, such as those environments present for the Airborne Laser. Kinematic mounts supporting these components are a desirable design fea ...

This proposal deals with new techniques for the guidance and control of Boost Phase of the missile defense. A new concept integrating the synergy between guidnace and coontrol is offered as an Integrated Guidance and Control approach; furthermore, a new nonlinear controller-filter called the theta-D technique is offered as the tool to solve the boost phase guidance and control problem for accurate ...

The pressing need exists within industry to accurately measure high aspect ratio microscale structures. For example, diesel injector nozzles are manufactured with microscale holes ranging from 50-200 micrometers in diameter and 3-5 mm depths. One fundamental challenge is to nondestrucvely measure these features in order to validate models, enhance manufacturing processes, and reduce fuel emissions ...