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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Human monoclonal antibodies as countermeasures for T-2 mycotoxin

    SBC: ABZYME THERAPEUTICS LLC            Topic: CBD152003

    Mycotoxins are fungal toxins to which exposure frequently results in incapacitation or even in death. Natural outbreaks of mycotoxin poisoningare common worldwide. Due to its physical-chemical properties, high toxicity and relative ease to produce, mycotoxin T-2 is classified as apotential biological warfare agent. Currently there are no FDA approved medical countermeasures available for T-2 mycot ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  2. Protein Qspec: An Improved Method for Rapid Characterization of Protein Aggregates in Biologic Drugs for Increased Quality and Safety

    SBC: OPTOFLUIDICS, INC.            Topic: 90201

    Optofluidics will develop Protein Qspec, a new particle analysis QC instrument designed to characterize protein aggregates in biologic drugs. The primary concern for this class of therapeutics is that they can elicit an immune response from patients who develop anti-drug antibodies which can eliminate the therapeutic benefit. The presence of particulate matter, in these therapeutics (e.g. shed gla ...

    SBIR Phase I 2016 Department of CommerceNational Institute of Standards and Technology
  3. Probabilities of Business Impact Variables from CFS2 Ensembles

    SBC: PRESCIENT WEATHER LTD            Topic: 831

    The value of the subseasonal and seasonal probability (S2S) forecasts of the NWS Climate Forecast System Version 2 (CFS2) will increase substantially when they are converted into forecasts about business impact variables such as degree days, wind and solar power potential, end-of-season crop yield, water resource variables, and extremes of both weather and impacts themselves. In Phase II, our Phas ...

    SBIR Phase II 2016 Department of Commerce
  4. Satellite ground station network for real-time space weather data

    SBC: USML L.L.C.            Topic: 843

    The goal of this project is to determine the feasibility of developing a ground station network capable of delivering real time space weather data to end users. Specifically, the proposed works seek to assess existing and future communications requirements for providing better than 15 minute latency (threshold objective) for transfer of data from NOAA space weather assets to the ground for distrib ...

    SBIR Phase I 2016 Department of Commerce
  5. Signal Processing for Layered Sensing

    SBC: VADUM INC            Topic: CBD152006

    In Phase I, Vadum will develop a signal processing module designed to fuse data from multiple heterogeneous, multi-tiered sensors, as well as asoftware prototype demonstrating the automation of the fusion process for presentation to a Brigade Chemical Biological Radiological Nuclear(CBRN) analyst. The techniques developed will incorporate Chemical/Biological (CB) agent detection sensors, non-CB se ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  6. Single domain antibodies as medical countermeasures for viral induced encephalitis

    SBC: ABZYME THERAPEUTICS LLC            Topic: CBD161004

    Alphavirus infection, which may cause encephalitis and death, are recognized as potential biological warfare agents. There are no approved medical countermeasures against diseases caused by Alphaviruses. In this project, thermostable single domain antibodies capable of crossing the blood brain barrier (BBB) and neutralizing encephalitic viruses will be developed using Abzymes proprietary in vivo S ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  7. Contaminated Materiel Transfer Case

    SBC: PRODUCTION PRODUCTS MANUFACTURING & SALES CO., INC.            Topic: CBD161006

    With the global reach of our US military and civilian population, with the threat of use of chemical and biological warfare, and the spread of deadly viruses in the world; it has become necessary to have containment options for large scale transport of hazardous/contaminated materials that meet the strict national, international and US Air Force standards for air transport. In this Phase I SBIR, P ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  8. Decontamination Assurance Spray

    SBC: AGENTASE LLC            Topic: CBD05103

    There are many products that can identify chemical weapons. They range in complexity from simple colorimetric chemical test strips or gas tubes, to more complex multi-step test kits, to intricate arrays of gas chromatographs and mass spectrometers. None of the products is specifically designed to illustrate the presence of chemicals on surfaces or have use as a decontamination assurance method. ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  9. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  10. Filovirus drug discovery using novel combinations of approved drugs

    SBC: APATH, LLC            Topic: CBD05119

    The goal of this proposal is find novel combinations of approved drugs for the treatment and/or prevention of infection with filoviruses. Ebola and Marburg viruses, the only filoviruses, cause an acute hemorrhagic fever syndrome which has a high mortality rate and poses a significant bio-terrorism threat. There are currently no therapeutic agents available to treat filovirus infections and the de ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
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