Award Data

The objective of this SBIR Phase I proposal is to determine the feasibility of viscosity characterization of high concentration protein formulations (HCF) by QATCH’s microcapillary quartz technology. HCFs are non-Newtonian fluids with shear-thinning behavior and they are administered to patients by subcutaneous or muscular injections. The injectability of HCFs depends on the viscosity at high-sh ...

NOAA is pursuing sustained, in-situ sensing technology to support improved atmospheric modeling of the upper ocean boundary environment, including the air-sea interface, during turbulent storms. Improved atmospheric modeling in this critical region will lead to better forecasting and support NOAA's mandate to protect property and save lives. Small, unmanned aircraft, equipped with atmospheric sens ...

The S‐100 specification is a new geospatial standard for hydrographic data, that is presently under development by the International Hydrographic Organization (IHO). Once the S‐100 based products and services are fully developed by the IHO, current datasets will be scheduled for obsolescence, and the Hydrographic Offices (HOs) will no longer produce them. Companies offering e‐navigation solu ...

In this Phase II effort, PEMDAS Technologies and Innovations (PEMDAS), in collaboration with subcontractor Westover Studios, proposes to develop a functional prototype of the Weather “Action Chain” Enabler (ACE) application using the technologies identified, knowledge gained, and preliminary design conceived during the Phase I effort. As designed, the Weather ACE application will be a non-intr ...

Electro-optical infrared and long wavelength infrared detectors and sensors are increasingly important for the Chemical/Biological Defense community. Solid-state optical cooler materials are in demand for replacing mechanical closed cycle coolers used in current LWIR standoff sensors to achieve cryogenic temperatures. Recent advances in optical cooling of rare-earth doped materials are pointing to ...

The proliferation of weapons of mass destruction (WMDs) presents a serious security threat to U.S. and allied personnel around the world. Military personnel and first responders must be prepared to operate under a wide range of chemical, biological, radiological, nuclear (CBRN) threats. Commercially available CBRN protective suits are bulky offering little dexterity to the wearer, therefore new st ...

In response to the defined need for minimizing the carry weight of combat teams while retaining capability, Luna Innovations is proposing the development of a stable formulation of atropine and scopolamine for use in an autoinjector to combat nerve agent intoxication. The combined formulation of atropine and scopolamine will allow for better treatment with more physiological coverage within the hu ...

Luna Innovations is addressing the need to develop novel fluid repellent textile treatments for military uniforms that will repel and actively decontaminate chemical and biological warfare agents (CBWA). There have been recent significant advances in textile treatments that have demonstrated water, oil and chemical agent resistance that are superior to Quarpel repellent treatments currently used o ...

Nerve agents exert their toxic effect by binding to and inactivating enzyme acetylcholinesterase, a key enzymatic regulator of cholinergic neurotransmission. The binding becomes irreversible after a varying amount of time with nerve agents and this aging process limits the treatment window of oxime reactivators. To enhance the current antidote treatment of nerve agent autoinjectors, a pyridostigmi ...

DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...