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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Filovirus drug discovery using novel combinations of approved drugs

    SBC: APATH, LLC            Topic: CBD05119

    The goal of this proposal is to find novel combinations of approved drugs for the treatment and/or prevention of infection with filoviruses. Ebola and Marburg viruses, the only filoviruses, cause an acute hemorrhagic fever syndrome which has a high mortality rate and poses a significant bio-terrorism threat. There are currently no therapeutic agents available to treat filovirus infections and the ...

    SBIR Phase II 2006 Department of DefenseOffice for Chemical and Biological Defense
  2. Construction of a Force Probe for Characterization of Microscale Features

    SBC: INSITUTEC, INC.            Topic: N/A

    The Phase 2 objective is to provide NIST with a modular gauge head unit equipped with InsituTec's standing wave probe technology. The complete gauge head unit will be retrofitted to the NIST M48 which is one of the most precise measuring machines in the world. This unit will enable NIST to achieve the agency's program goal in dimensional metrology which is to provide microscale measurement capacit ...

    SBIR Phase II 2006 Department of CommerceNational Institute of Standards and Technology
  3. A Multivalent Bacterial Vaccine for Atlantic Cod

    SBC: Maine BioTek, Inc.            Topic: 8111

    The goal of this project (Phase I ¿ III) is to develop a vaccine for the control of diseases in Atlantic cod caused by L. anguillarum and A. salmonicida. To accomplish this we have established the following sequential technical Phase I objectives: (1) identify bacterial growth conditions suitable for small-scale vaccine production, (2) determine the conditions for inactivation that result in the ...

    SBIR Phase I 2006 Department of Commerce
  4. Handheld FT-IR/Photoacoustic Chemical Agent Detector

    SBC: MANNING APPLIED TECHNOLOGY            Topic: CBD05112

    Manning Applied Technology proposes development of the MP-100 handheld FT-infrared photoacoustic chemical agent detector, following a highly successful Phase I effort. Chemical attacks and accidents can be mitigated partially by cost-effective sensors. High priority programs will benefit from a sensor compliant to Joint Warning & Reporting Network (JWARN) standards. The device is ideally suited to ...

    SBIR Phase II 2006 Department of DefenseOffice for Chemical and Biological Defense
  5. User-Friendly 3D Environmental Profiler AUV

    SBC: NEKTON RESEARCH LLC            Topic: 813

    We propose Ranger ES, a low cost, autonomous underwater vehicle (AUV) for three-dimensional profiling and water samplings of chemical, physical, and biological parameters of oceanic and fresh waters. The AUV will be programmable by point and click to analyze a volume of water continuously for the selected parameters. After returning for pickup after a day¿s run, it will download its data into a ...

    SBIR Phase I 2006 Department of Commerce
  6. Realtime Detection And Identification Of Airborne Microorganisms Using Infrared Spectroscopy

    SBC: Orono Spectral Solutions Inc.            Topic: CBD06102

    The goal of this Phase I effort is to investigate the feasibility of extracting at least 1.0 microgram of bacillus spores from the environment and presenting these spores in real-time to an FTIR spectrometer for detection. The identification of bacterial spores using FTIR spectroscopy has been successful in classifying these microorganisms down to the genus and species level. Therefore the key e ...

    SBIR Phase I 2006 Department of DefenseOffice for Chemical and Biological Defense
  7. Analysis Tools for Detection and Diagnosis of Biological Threats

    SBC: ALPHA-GAMMA TECHNOLOGIES, INC.            Topic: CBD04113

    DNA microarray technology, in combination with statistical and predictive modeling tools, could be used to evaluate thousands of genes against distinct gene expression patterns induced by chemical/biological agents to provide early identification and speed therapeutic intervention. The overall objective of this Phase II effort is to leverage existing public domain resources and commercial tools t ...

    SBIR Phase II 2005 Department of DefenseOffice for Chemical and Biological Defense
  8. Filovirus drug discovery using novel combinations of approved drugs

    SBC: APATH, LLC            Topic: CBD05119

    The goal of this proposal is find novel combinations of approved drugs for the treatment and/or prevention of infection with filoviruses. Ebola and Marburg viruses, the only filoviruses, cause an acute hemorrhagic fever syndrome which has a high mortality rate and poses a significant bio-terrorism threat. There are currently no therapeutic agents available to treat filovirus infections and the de ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
  9. Construction of a Force Probe for Characterization of Microscale Features

    SBC: INSITUTEC, INC.            Topic: N/A

    The pressing need exists within industry to accurately measure high aspect ratio microscale structures. For example, diesel injector nozzles are manufactured with microscale holes ranging from 50-200 micrometers in diameter and 3-5 mm depths. One fundamental challenge is to nondestrucvely measure these features in order to validate models, enhance manufacturing processes, and reduce fuel emissions ...

    SBIR Phase I 2005 Department of CommerceNational Institute of Standards and Technology
  10. Handheld Photoacoustic Chemical Agent and Toxic Industrial Material Detector

    SBC: MANNING APPLIED TECHNOLOGY            Topic: CBD05112

    Manning Applied Technology proposes to develop a handheld infrared spectrometer, ideally suited to detection of airborne chemical agents at and below permissible exposure limits. This approach offers unmatched sensitivity and specificity for detection of all types of chemical vapors. The instrument is modular, rugged, compact and highly sensitive. Volume pricing will be less than $1000 each. ...

    SBIR Phase I 2005 Department of DefenseOffice for Chemical and Biological Defense
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