Award Data

Our goal is to develop a first-of-its-kind, commercial, model-based design tool to enable digital engineering of solar cells and modules. We will leverage and adapt Plato1 – an open-source2 software developed at Sandia National Laboratories to support multidisciplinary design, analysis, and optimization in high performance computing environments – to accelerate software development proposed he ...

C55-10a-270371Electron Tomography (ET) is used to visualize nanostructures in three dimensions, but long acquisition times make it unsuitable for the study of fast in situ reactions and dose-sensitive materials. The limiting factor for fast acquisition of ET data is stage instability causing drift in all directions while tilting. Because ET requires many images taken within the exact same field of ...

C55-05a-270492-AbstractChemical reactions are rarely performed in isolation. Most real-world applications involve chemical reaction networks in which many simultaneous chemical reactions of many species occur. Advances in high-performance computer simulations and laboratory automation provide an increasingly detailed picture of these chemical reaction networks, but the underlying representation in ...

Wellbores that intersect CO2 storage formations represent a potential leakage pathway that can lead to subsurface migration of stored CO2 and/or subsequent venting of stored CO2 to the surface; consequently, repair and remediation of these wellbore is critical for ensuring the permanent storage of CO2 in geologic formations. Repair and remediation operations are particularly challenging for these ...

C55-05a-270698Computational methods and tools applied to mine data are critical for the economic growth and security of our nation. Advanced machine learning (ML) and artificial intelligence (AI) algorithms are applied to automate the mining of zettabytes of internet data. However, the mining of the much more limited, highly heterogeneous, multimodal, disparate, uncertain, non-uniform, and unstruc ...

U.S. Department of Energy (DOE) is developing innovative, flexible, and small-scale (1-5 MW), modular gasification systems for converting diverse types of US domestic energy resources into value-added products with greatly reduced or negative CO2 emissions. Production of high purity (>95%) oxygen at modular scale is an enabling technology for successful development and deployment of these systems. ...

Biological imaging with molecular specificity is most often achieved using fluorescent labeling. Fluorescent light for image contrast is also the basis of most optical “super-resolution” techniques that achieve far-field spatial resolution beyond the classical limit. However, non-invasive imaging techniques have been developed that use only native fluorophores, or bypass fluorescence in favor ...

Statement of the problem or situation that is being addressed: Critical to the development of biofuels is understanding the chemical and physical environments within individual plant cell or organelles as well as cellular interactions with its environment. The ability to track the chemical exchanges between plant cells and microbial communities in environmental settings could improve the efficienc ...

C53-28a-271090Biological systems function across scales, with operations at nanoscales coming together to form complex macroscale communities. Thus, resolving interactions and tracking metabolic processes within living systems requires multi-scale imaging to visualize cells at the community, cellular, subcellular, and single-molecule scales. Although techniques like light sheet fluorescence micros ...

C53-28b-271112Quantum enabled approaches pose new concepts for bioimaging and sensing of biological processes in living biological systems, non-destructively in real time. Processes of interest for bioenergy include measuring enzyme function within cells, tracking metabolic pathways in vivo, monitoring the transport of materials into and out of cells or across cellular membranes and, measuring sig ...