List

Distributed Spacecraft Missions (DSM) architectures provide unique scientific and programmatic benefits including multipoint in-situ measurements, multi-angle viewpoints, and improved understanding of the connections between separately measured phenomena and their time variations. However, these missions impose significant operational demands on ground tracking resources and mission operators alik ...

The objective of this SBIR Phase I proposal is to determine the feasibility of viscosity characterization of high concentration protein formulations (HCF) by QATCH’s microcapillary quartz technology. HCFs are non-Newtonian fluids with shear-thinning behavior and they are administered to patients by subcutaneous or muscular injections. The injectability of HCFs depends on the viscosity at high-sh ...

We will develop a series of object manipulation primitives to pick up and assemble standard mechanical parts such as screws, gears and pulleys that can be configured without any programming skills. Building up on a smart robotic gripper, 3D perception and machine learning algorithms, we will design a graphical user interface for the Universal Robot E-Series that allows an user to label arbitrary 3 ...

The objective of this proposal is to develop an electronic, rule-based clinical decision support system (CDS-Sx) that leverages national clinical practice guidelines (CPGs) to improve cancer symptom management. Specific tasks that will be performed include: 1) create software-ready computable algorithms for managing cancer-related fatigue and constipation that have been vetted with diverse cancer ...

Colorectal Cancer (CRC) is the third most common cancer both in men and women, as well as the second leading cause of cancer deaths with an estimated 135,430 new cases diagnosed and 50,260 deaths for 2017 in the United States. Given the limitations of screening tests and poor prognosis associated with advanced stage colorectal cancer, it would be of great interest in exploring chemoprevention stra ...

A critical remaining challenge toward a true cure for HIV is understanding how latently infected cells evade the immune system and persist as lifelong viral reservoirsOne eradication strategythe so calledshock and killapproachrelies on cell activating compounds to reverse latent infectionand subsequent antiretroviral therapy to eradicate newly activated cellsHoweverthese compounds activate only a ...

There currently lack diagnostic tools with necessary sensitivity for use in the elimination and post elimination efforts for malaria and other Neglected Tropical DiseasesNTDsMicroscopy and rapid diagnostic testsRDTshave been largely adequate for malaria control and case management but lack the sensitivity to detect low density infectionsAsymptomatic individuals with chronic infection remain reserv ...

The MarsOasis™ cultivation system is a versatile, autonomous, environmentally controlled growth chamber for food provision on the Martian surface.  MarsOasis™ integrates a wealth of prior research and Mars growth chamber concepts into a complete system design and operational prototype.  MarsOasis™ includes several innovative features relative to the state of the art spa ...

Reducing the allowable concentration of carbon dioxide (CO2) in spacecraft is a critical need for NASA.  The system now used on the International Space Station (ISS) is the carbon dioxide removal assembly (CDRA).  While it has performed well on the ISS, managers have concluded that using the device to reach the new ppCO2 limit of 2.0 mm Hg is not practical and a new method is needed.In t ...

Opterus Research and Development, Inc. proposes to develop and validate multi-scale thin-ply High Strain Composites (HSCs) constitutive modeling tools for incorporation into commercial finite element analysis codes. The constitutive models will capture the time-temperature-load-deformation viscoelastic characteristics common to HSCs as well as the yielding or permanent deformation associ ...