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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Dynamically Scaled Model for NASA's Next Generation Aviation Demonstrator

    SBC: Sensintel Inc.            Topic: T701

    Significant advances in several key technologies such as material sciences, manufacturing, miniaturization, and active flow control suggest that the time has come to address the issue of affordable General Aviation (GA). These new technologies when combined with advanced avionics and propulsion concepts will make GA affordable and ecologically sustainable. With a greater ease of vehicle operation, ...

    STTR Phase I 2006 National Aeronautics and Space Administration
  2. Nanoliter Lab-on-a-chip for Protein Crystallization

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): The human genome contains at least 30,000 unique open reading frames that may yield >100,000 polypeptide products. These products assemble into more than a million biologically relevant structures or proteins of interest per organism. Crystallization and X-ray diffraction of these proteins is routinely performed to determine their 3D structure which needs to be ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Nanoliter Lab-on-a-Chip for Blood Diagnostics

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): Latrogenic blood loss or "bleeding into the laboratory" is an important reason for administration of small volume transfusions in very low birth weight premature 6infants. A direct correlation was found between the volume of blood drawn for diagnostics and subsequent volume transfused. In neonatal infants, there may not be enough collected blood sample to perfo ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Portable Programmable Multifunction Body Fluids Analyzer

    SBC: ADVANCED LIQUID LOGIC            Topic: X1103

    Advanced Liquid Logic proposes to develop a very capable analyzer based on its digital microfluidic technology. Such an analyzer would be:  Capable of both simple and complex biological assays  Small, lightweight, power efficient, and easy to operate  Fully programmable and remotely reprogrammable Under NIH funding we have demonstrated clinical chemistry blood diagnostic testing on our ...

    SBIR Phase I 2006 National Aeronautics and Space Administration
  5. Nanoliter Lab-on-a-Chip for Rapid Parallel Immunoassays

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): The development of clinically effective cancer vaccines requires reliable analytical methods to evaluate the immune response to vaccination. Immunoassays are among the most sensitive and specific analytical methods that have been used widely in cancer vaccine research, most commonly to monitor the release of cytokines from T-cells in response to vaccination. A ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Gradient Interphase, 3-D Fiber Architecture CMC's

    SBC: 3TEX, Inc.            Topic: N/A

    A clear need exists for the next generation of Ceramic Matrix Composites (CMC) for Thermal Protection Systems (TPS), propulsion hardware, and other high temperature applications. No "off-the-shelf" materials and/or processes capable of meeting NASA's goals are available, yet completely integrating a unique combination of commercially available or nearly commercially available technologies can m ...

    STTR Phase I 2006 National Aeronautics and Space Administration
  7. Discovery of a Platelet Derived Growth Factor Peptide-based Mimetic

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Summary/Abstract Diabetic foot ulcers are a significant health problem that imposes high costs on both patients and society (Boulton, Vileikyte et al. 2005). A large proportion of foot ulcers remain unresponsive to available conventional treatment and their associated complications and costs have prompted extensive research that has led to promising breakthroug ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Click Chemistry for Immobilized Bone Morphogenetic Protein

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): There are over 6.3 million fractures each year in the United States of which approximately 700,000 are difficult to heal. The available treatment options for fractures that do not heal or are slow to heal are limited. Bone morphogenetic proteins are growth factors that stimulate new bone production and have received FDA approval for bone fracture repair and spi ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Improved Orthopedic Implant Surface Coatings

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Many contemporary medical and dental therapies include the replacement or repair of tissues using materials such as metal. Currently there are at least 150,000 hip replacements, 300,000 knee replacements, and 500,000 dental implant procedures performed in the US each year (Kurtz, Mowat et al. 2005). These numbers are expected to increase as the baby boom gen ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  10. Injectable BMP-2 Formulation for Fracture Healing

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Two recombinant human Bone Morphogenetic Proteins (BMP's), rhBMP-2 and rhBMP-7, are currently used in clinical applications to promote spinal fusion and fracture healing (Mont, Ragland et al. 2004). Over 6.3 million fractures occur each year in the United States alone (Praemer, Furner et al. 1999). Approximately 15% of fractures have delayed or impaired healing ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
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