Award Data

A lidar laser transmitter useful for profiling of clouds, aerosols, and differential absorption measurements of atmospheric trace constituents such as carbon dioxide, water vapor, and ozone is proposed. The proposed laser transmitter is based on a master tunable external cavity diode laser (ECDL) used to injection lock a series of free running laser diodes (FRLD's). The FRDL's amplify the injected ...

DESCRIPTION (provided by the applicant): Autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, type I diabetes, and multiple sclerosis, are thought to arise from abnormalities of innate or adaptive immune responses. Autoimmune diseases are often difficult to diagnose, as the symptoms can be typical of other conditions and quite vague, such as musculoskeletal complaints ...

DESCRIPTION (provided by applicant): Autoimmune diseases are difficult to diagnose, as the symptoms can be typical of other conditions and quite vague. No currently available blood test accurately excludes or includes the possibility of an autoimmune disease in a subject, and a battery of tests and a period of observation are usually required. A single test that could readily distinguish between ...

DESCRIPTION (provided by applicant): Pretest probability assessment plays an important role in the evaluation of pulmonary embolism (PE) in the emergency department (ED). Current methods of pretest probability assessment produce categories of risk that tend to over fit individual patients. The hypothesis of this work is that the pretest probability of PE can be accurately estimated by computerize ...

DESCRIPTION (provided by applicant): The Genomics Revolution and the resultant explosion of knowledge in genomics are shaping our futures. Therefore, it is crucial that knowledge of genomics is broadly disseminated, so that future scientists, educators, policy makers, community leaders, and heads of households can harness the beneficial power of genomic science. Given the indiscriminate impact of ...

DESCRIPTION (provided by investigator): This application seeks Phase II funding to continue the development of the Elementary School Success Profile (ESSP) Drug Abuse Prevention Sreening Tool. The long-term objective is to help school-based health and mental health professionals quickly and accurately assess students' risk and protective factor status for adolescent substance use and other harmfu ...

DESCRIPTION (provided by investigator): This application seeks Phase II funding to continue the development of the Elementary School Success Profile (ESSP) Drug Abuse Prevention Sreening Tool. The long-term objective is to help school-based health and mental health professionals quickly and accurately assess students' risk and protective factor status for adolescent substance use and other harmfu ...

DESCRIPTION (provided by applicant): Prostate cancer is the most common malignancy in men in the United States and the second leading cause of cancer mortality. Unfortunately there is no cure by standard medical treatment. Therefore, novel treatments for this devastating, common disease are desperately needed. Recent progress in the development of targeted oncolytic viral vectors offer a new strat ...

DESCRIPTION (provided by applicant): Despite continued improvements in diagnosis, surgical techniques, and radiation protocols, the available treatments for high-grade malignant glioma are grossly inadequate. The median survival time for most patients with high-grade gliomas is on the order of months. Metastatic tumors with a tropism for the CNS such as lung and breast pose an even greater problem ...

DESCRIPTION (provided by applicant): This proposal is being sent in response to NIMH PA-00-118. The objective of this proposal is to begin the commercialization process of a high performance reconfigurable signal-processing platform that will perform real-time on-line analysis of large-scale multi-channel data streams for data-driven neural simulations and modeling. The platform will be used to ai ...