Award Data

Bridger Photonics Inc. (Bridger) proposes to develop the most compact, efficient and low-cost ultra-violet ozone differential absorption lidar (DIAL) transmitter available. This system will use a frequency-doubled, conductively-cooled, q-switched Nd:YAG laser to pump a combination optical parametric oscillator (OPO) and sum frequency generation (SFG) cavity to deliver 6 ns, 1.5 mJ and 1 kHz puls ...

The proposed research pursues a path for reducing structural weight, increasing structural performance, and reducing fabrication cost while also minimizing maintainability. The approach, which is a based on selective reinforcement, is a change in the basic design philosophy and will result in the development of a hybrid material form. The selective reinforcement approach allows the structural de ...

This SBIR Phase I effort proposes to establish the feasibility of leveraging advances in compact laser technology with integration of space qualified techniques into AdvR's Planar Lightwave Circuit (PLC) and iodine reference cell technology for the design of a space qualifiable, frequency stabilized seed laser system in support of NASA Langley's High Spectral Resolution Lidar (HSRL) pr ...

DyMA-FM (Dynamic Multivariate Assessment for Fault Management) is a software architecture for real-time fault management. Designed to run in a distributed environment, DyMA-FM enables model-based reasoning and predictive modeling for FM applications. With the appropriate hardware, DyMA-FM can respond to signals at the device level while still placing each signals in context with the larger system ...

Innovative Imaging and Research and the University of Houston Clear Lake have teamed to develop a widely extensible, affordable, energy efficient, smart lighting device known as Lambda-Net. Smart building technologies, such as Lambda-Net, are becoming critical to energy savings and sustainability for terrestrial applications and space-based habitats. Our device incorporates a smart-mobile device ...

Quantifying oceanic CO2 uptake and ocean acidification and understanding their impact on global climate and ocean ecology are key goals of NOAA’s climate change research programs. NOAA’s request for Development of a long-term Lagrangian pH and pCO2 drifter (SBIR Subtopic 8.3.1C) aims to address these goals by developing technology that measures both pCO2 and pH that can be widely deployed in t ...

In Phase I, a novel porous electrode was designed to demonstrate a rapid, simple assay for the detection of domoic acid in marine samples. During Phase II, methods to manufacture porous electrodes will be improved to enable high volume production of low-cost biosensors that can be connected to a potentiostat. These biosensors will be incorporated into a portable test kit for the quantitation of do ...

DESCRIPTION (provided by applicant): Alzheimer's disease (AD) is a progressive and ultimately fatal neurodegenerative disease that affects more than five million people in the USA. Currently there is no cure for AD. Available medicines are aimed only at temporarily reducing symptoms and slowing down the progression of the disease. While many new compounds have been developed to treat AD, they ...

DESCRIPTION (provided by applicant): Standard microfracture is a first-line, widely used and cost-effective surgical technique for repairing damaged articular cartilage, but, it is limited by decreased long-term efficacy and limited applicability in largerlesions. This leads to a burgeoning economic burden associated with primary and follow-up treatment costs, estimated at more than 40 billion dol ...

DESCRIPTION (provided by applicant): Controlling mechanical signal transduction to treat osteoarthritis Abstract The TRPV4 calcium (Ca++) permeable ion channel has been shown to be expressed and functional in chondrocytes, the cells responsible for the maintenance of cartilage in weight-bearing joints. Trauma of joints with subsequent damage of cartilage, as well as chronically increased joint loa ...