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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Compact, Waveguide Based Programmable Optical Comb Generator

    SBC: ADVR, INC.            Topic: T401

    This NASA Phase I STTR effort will establish the feasibility of developing a compact broadband near to mid-IR programmable optical comb for use in laser based remote sensing and communications. The comb generator will use a waveguide-based optical parametric gain block technology that can have ultra wideband (>250nm) operation with very high gain (>25dB) in a very compact footprint. This approach ...

    STTR Phase I 2010 National Aeronautics and Space Administration
  2. Walker Monitor to Inhibit Freezing of Gait by Individuals with Parkinson's Diseas

    SBC: VORTANT TECHNOLOGIES LLC            Topic: NIA

    DESCRIPTION (provided by applicant): Freezing of Gait (FOG) effects the majority of the approximately one million individuals who have Parkinson's disease nationwide and causes a cessation of movement that patients describe as feeling as if their feet are glued to the ground . FOG most often occurs in the mature stages of Parkinson's disease and results in a loss of balance and severe falls. Thes ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Evaluation of NBD Peptides as an Adjunct Therapy for the Treatment of Non-Hodgkin

    SBC: THERALOGICS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The NF-?B family of transcription factors plays a central role in the regulation of lymphocyte proliferation, differentiation and survival. Aberrant constitutive activation of NF-?B has been identified in many different aggressive lymphoid malignancies in humans and contributes to lymphomagenesis and chemotherapeutic resistance by driving the expression of NF-? ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Novel Phosphate Binder: Effects on Hyperphosphatemia, Vascular Calcification and Bo

    SBC: BIOLINK LIFE SCIENCES INC            Topic: NIDDK

    DESCRIPTION (provided by applicant): In patients with chronic kidney disease (CKD), phosphate retention may contribute to progression of renal failure and is a major factor in the development of secondary hyperparathyroidism and vascular calcification. Progression of injury is causally associated with risk of mortality that is estimated 10 to 30 times higher for CKD patients undergoing dialysis th ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  5. Novel Optical Microprobes for Ultra-Precise Intraocular Laser Surgery

    SBC: PhotonTech, LLC            Topic: NEI

    DESCRIPTION (provided by applicant): This STTR project proposes to develop a novel optical scalpel for ultra-precise ophthalmic laser surgery. Segmentation and removal of epiretinal membranes during vitreoretinal surgery is currently performed mechanically with both blunt and sharp dissection, which causes collateral damage to healthy retinal tissue. Conventional fiber-based surgical laser micropr ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. The effect of TLR4 inhibition on lung transplant ischemia-reperfusion injury

    SBC: X-IN8 BIOLOGICALS CORPORATION            Topic: NHLBI

    DESCRIPTION (provided by applicant): Ischemia-reperfusion injury (IRI) occurs in organs when circulation is interrupted, causing ischemia, and then ischemic tissue is reperfused. This leads to a series of biologic consequences, resulting in edema and inflammation. IRI is a significant problem in organ transplantation, because IRI is the major cause of primary graft failure and organ dysfunction af ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Development and Testing of Recombinant Clostridia for Cancer Therapy

    SBC: SGM BIOTECH, INC.            Topic: NCRR

    DESCRIPTION (provided by applicant): This STTR application is to develop and test for eventual clinical use a new strategy for tumor specific anticancer drug delivery. The technology, Clostridia-directed enzyme prodrug therapy, or CDEPT, exploits the fact that certain non-pathogenic bacteria of the Clostridia genus, which only grow in the absence of oxygen (hypoxia), colonize the hypoxic and necr ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  8. N/A

    SBC: FLYING BRIDGE TECHNOLOGIES            Topic: N/A

    N/A

    STTR Phase I 2000 Department of Health and Human ServicesNational Institutes of Health
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    SBC: RESODYN CORPORATION            Topic: N/A

    N/A

    STTR Phase I 2000 National Aeronautics and Space Administration
  10. N/A

    SBC: TRIANGLE LABORATORIES, INC.            Topic: N/A

    N/A

    STTR Phase I 2000 Department of Health and Human ServicesNational Institutes of Health
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