Award Data

ABSTRACT Improving Anticoagulation Monitoring in Pediatric Patients: Use of a Microfluidic Platform to Test Low Volume Blood Samples Obtained by Heel-Stick Collection Children treated for congenital heart defects or other disorders of hypercoagulation are prescribed unfractionated heparin (UFH) or low molecular weight heparin (LMWH) throughout surgical treatment; they may be prescribed heparin for ...

Sustainable Bioproducts (SBP) has developed a simple and energy efficient bioreactor technology for the purpose of supporting NASArsquo;s in-situ microbial manufacturing needs. The technology capitalizes on the robust nature of filamentous fungi grown as biofilms. SBP has shown that the system can be used to convert a multitude of mission available feedstocks into dense, easily harvestable biomats ...

The main focus of this SBIR Phase II project is to develop a prototype instrument and test cartridges for injectability pre-screening of high concentration protein formulations (HCFs). HCFs are non-Newtonian fluids with shear-thinning behavior and they are formulated to be administered by subcutaneous or muscular injections. The injectability and manufacturability of HCFs depend on the viscosity b ...

Ultrasonic Technology Solutions (UTS) aims to develop a transformative human solid waste management system for the International Space Station (ISS) that uses our unique, efficient and fast direct-contact ultrasonic drying method. Human metabolic solid waste (feces) contains 75% water by mass which is currently not recovered on the ISS and is instead transported back to earth. Return transportatio ...

In this phase I effort ultra-light BHL composite transfer lines were shown to reduce chill-down time over 90% compared to equivalent stainless steel lines. BHL tubes have frac14; the mass of comparable systems, and 5-10 times less thermal mass. These benefits are also applicable to BHL tanks. The use of BHL in cryogenic storage and transfer systems will significantly reduce propellant required for ...

As governments and commercial entities compete for opportunities to travel to Mars and throughout deep space, the need for more efficient engines, reduced launch weight and increased payload capacities are constantly being developed. NASA is re-engaging its interest in Nuclear Thermal Propulsion because of its promise to double the efficiencies of competing engine types and fuels including higher ...

Modeling aircraft aeroelastic response is an incredibly challenging process fraught with many questions regarding the approaches and assumptions in both structural and aerodynamic analyses.nbsp; Modeling 3-D, full scale, fully coupled, aerodynamic and structural responses with high-fidelity computational approaches is only viable for evaluating a few conditions within the flight envelope, but intr ...

GTLrsquo;s ultralightweight BHLtrade; dewar provides dramatically reduced mass, and increased performance over metal dewars. In cryogenic propellant storage systems, BHL has a demonstrated mass reduction of 75%. A similar mass reduction is expected for dewar applications. BHL allows thinner carbon fiber plies to be used, reducing mass and thermal mass while also increasing thermal resistance. Vary ...

Real-time, high-frequency measurements of atmospheric ozone are becoming increasingly important to understand the impact of ozone towards climate change, to monitor and understand depletion of the ozone layer, to further understand its role in atmospheric chemistry, and to assess its impact on human health and the productivity of agricultural crops. Expansions of tropospheric ozone measurement eff ...

nbsp;For over 10 years GTL has been developing novel rocket system components. Originally funded by DARPA, with additional funding by NASA, GTL has developed a novel composite system (BHLtrade;) for cryogen storage and transfer. BHL is used to produce LOX and cryogen compatible components that leverage the full strength of carbon fiber. For ground systems, the reduction in thermal mass will be mor ...