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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Lab-on-a-chip for multiplexed newborn screening of lysosomal storage disorders
SBC: ADVANCED LIQUID LOGIC Topic: N/ADESCRIPTION (provided by applicant): Newborn screening is currently performed by collecting dried bloodspots from infants and then sending them to a lab for analysis. There is an increasing necessity to screen for a number of disease conditions for which therapies are becoming available. Lysosomal storage diseases alone number greater than 40. There is a need to minimize the blood collecte ...
SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health -
Interfacial Adapters for Improved Cell Delivery to Tissues
SBC: AFFINERGY, LLC Topic: N/ADESCRIPTION (provided by applicant): Many human diseases can theoretically be treated by injection of healthy or engineered cells into damaged tissue, where ideally they will engraft and remodel the damaged tissue into healthy tissue. However, numerous obstacles stand in the way of this regenerative technology becoming reality. Perhaps the greatest obstacle is that cells injected into many tissues ...
SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health -
Point of Care Attachment of Multiple Antibiotics onto Metal Implants
SBC: AFFINERGY, LLC Topic: N/ADESCRIPTION (provided by applicant): Infection surrounding metal implants is a common and sometimes devastating cause of implant failure in a number of fields including oral, craniomaxillofacial (CMF), orthopedic, and cardiovascular surgery. These infections, which arise from the establishment of biofilms on device surfaces, not only necessitate new surgeries but in themselves present a significan ...
SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health -
Bioactive Peptide Coatings for Synthetic Bone Grafts in Dental Applications
SBC: AFFINERGY, LLC Topic: N/ADESCRIPTION (provided by applicant): According to the National Institute of Dental and Craniofacial Research, 86% of adults over 70 years have at least moderate periodontitis and over a quarter have lost their teeth, which has serious repercussion on health and quality of life. Because of bone loss caused by this disease, bone grafting is routinely necessary prior to the placement of dental implan ...
SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health -
Point of Care Adult Stem Cell Isolation
SBC: AFFINERGY, LLC Topic: N/ADESCRIPTION (provided by applicant): Approximately 500,000 bone-grafting procedures are performed each year in the United States (Boden, 2002). Autologous iliac crest bone graft continues to be the gold standard because it provides the three essential elements for bone formation: osteoprogenitor cells, an osteoconductive matrix, and osteoinductive molecules. Iliac crest harvest is however associat ...
SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health -
Full Range Spectral Domain Anterior Segment OCT Scanner
SBC: BIOPTIGEN, INC. Topic: N/ADESCRIPTION (provided by applicant): In this Phase I Small Business Innovative Research application, Bioptigen Inc. proposes to prototype a portable, handheld cornea and anterior segment optical coherence tomography (CAS-OCT) scanner for use in clinical and applied research applications. OCT is a relatively new technology for ophthalmic imaging, which uses low-coherence interferometry to obtain cr ...
SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health -
Medical Student Education on Alcohol Abuse and Dependence
SBC: Clinical Tools, Inc Topic: N/ADESCRIPTION (provided by applicant): Alcohol use disorders continue to be a growing problem in the United States. Fifty-three percent of Americans consume alcohol on a regular basis (SAMHSA, 2006). Approximately 6 percent of those users meet the criteria f or alcohol abuse or dependence (SAMHSA, 2005); 3 percent of the U.S. population. Currently, alcohol use disorders are only covered superficiall ...
SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health -
Novel Intervention for Amyloid-Induced Neuroinflammation
SBC: COGNOSCI INC Topic: N/ADESCRIPTION (provided by applicant): Novel Intervention for Amyloid-Induced Neuroinflammation Extracellular deposition of the amyloid a-protein (Aa) in brain is a prominent pathological feature of Alzheimer's disease (AD) and related disorders. Fibrillar Aa deposition in the cerebral vasculature, a condition known as cerebral amyloid angiopathy (CAA), is also commonly found in AD. Additionally, se ...
STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health -
Novel Intervention for Colitis
SBC: COGNOSCI INC Topic: N/ADESCRIPTION (provided by applicant): Novel Intervention for Colitis The scope of the current proposal is to determine whether administration of an apoE mimetic peptide, COG112, improves clinical, histological and inflammatory outcomes in clinically relevant paradigms of colitis. Specifically, we will employ the acute Citrobacter rodentium (C. rodentium) model, an acute Dextran Sulfate Sodium (DSS) ...
STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health -
Novel Treatment for Parkinson's Disease
SBC: COGNOSCI INC Topic: N/ADESCRIPTION (provided by applicant): Parkinson's Disease (PD) is a devastating neurodegenerative disorder that affects approximately 500,000 people in the US and an additional 50,000 are diagnosed each year. This disease is characterized by tremors in the limbs, bradykinesia, akinesia, rigid limbs, and a shuffling gait. The symptoms of PD are caused by the destruction of dopaminergic neurons in th ...
SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health