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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Lab-on-a-chip for multiplexed newborn screening of lysosomal storage disorders

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): Newborn screening is currently performed by collecting dried bloodspots from infants and then sending them to a lab for analysis. There is an increasing necessity to screen for a number of disease conditions for which therapies are becoming available. Lysosomal storage diseases alone number greater than 40. There is a need to minimize the blood collecte ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  2. Interfacial Adapters for Improved Cell Delivery to Tissues

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Many human diseases can theoretically be treated by injection of healthy or engineered cells into damaged tissue, where ideally they will engraft and remodel the damaged tissue into healthy tissue. However, numerous obstacles stand in the way of this regenerative technology becoming reality. Perhaps the greatest obstacle is that cells injected into many tissues ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  3. Point of Care Attachment of Multiple Antibiotics onto Metal Implants

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Infection surrounding metal implants is a common and sometimes devastating cause of implant failure in a number of fields including oral, craniomaxillofacial (CMF), orthopedic, and cardiovascular surgery. These infections, which arise from the establishment of biofilms on device surfaces, not only necessitate new surgeries but in themselves present a significan ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  4. Bioactive Peptide Coatings for Synthetic Bone Grafts in Dental Applications

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): According to the National Institute of Dental and Craniofacial Research, 86% of adults over 70 years have at least moderate periodontitis and over a quarter have lost their teeth, which has serious repercussion on health and quality of life. Because of bone loss caused by this disease, bone grafting is routinely necessary prior to the placement of dental implan ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  5. Point of Care Adult Stem Cell Isolation

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Approximately 500,000 bone-grafting procedures are performed each year in the United States (Boden, 2002). Autologous iliac crest bone graft continues to be the gold standard because it provides the three essential elements for bone formation: osteoprogenitor cells, an osteoconductive matrix, and osteoinductive molecules. Iliac crest harvest is however associat ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  6. Digitally Enhanced Microscope for Crystal Detection

    SBC: APPALACHIAN ELECTRONIC INSTRUMENTS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to investigate, design and manufacture a sophisticated, pre-production protein crystal detection microscope, the Crystal Finder(tm) microscope workstation, incorporating extinction polarization and quantitative birefringence imaging for digitally enhanced display of crystal bulk contrast (referred to herein as Detect-X(tm) technology). Many protein c ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  7. Full Range Spectral Domain Anterior Segment OCT Scanner

    SBC: BIOPTIGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): In this Phase I Small Business Innovative Research application, Bioptigen Inc. proposes to prototype a portable, handheld cornea and anterior segment optical coherence tomography (CAS-OCT) scanner for use in clinical and applied research applications. OCT is a relatively new technology for ophthalmic imaging, which uses low-coherence interferometry to obtain cr ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  8. Expired CO2/O2 Analysis to Diagnose Pulmonary Embolism

    SBC: BREATHQUANT MEDICAL SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A rapid, noninvasive, and accurate, point-of-care device to diagnose and exclude pulmonary embolism (PE) remains an unmet need, especially for patients with conditions that activate inflammatory and coagulation pathways and therefore predispose to PE. These conditions include surgery, cancer, age >70 years, prolonged hospitalization, hemodialysis, connective ti ...

    STTR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  9. Spectroscopic presciption verification system

    SBC: CENTICE CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Prescription dispensing errors at a pharmacy are a problem on a national level, at a rate of about 4 errors per day in a pharmacy filling 250 prescriptions daily. This translates to a gigantic amount of 51 million prescription errors per year with about 3 billion prescriptions being filled. There are as many as 7,000 deaths reported annually in the United State ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  10. Rapid point-of-care diagnostic reader for Surface enhanced Raman nanotags in a la

    SBC: CENTICE CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Centice Corporation has developed a powerful, integrated approach to portable, yet sensitive, spectroscopic detection. Combined with novel optical detection tags based on surface enhanced Raman scattering (SERS), these two components can be synergized to create a highly multiplexed, handheld, diagnostic immunoassay system. In this grant proposal, as just one il ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
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