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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Clinical Development of a Therapeutic Agent for COPD


    DESCRIPTION provided by applicant Hypersecretion of mucus into the respiratory airways is a major contributing factor in several lung diseases including chronic pulmonary disease COPD asthma cystic fibrosis allergic rhinitis and bronchiectasis Despite the obvious medical importance there presently are no effective therapies to control excess mucus secretion in these diseases and very ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Improved diagnostic and monitoring assays for thyroid cancer

    SBC: Soymeds Inc            Topic: NCI

    DESCRIPTION provided by applicant Thyroid cancer is the most common type of endocrine malignancy New thyroid cancers patients are identified daily and most patients live for decades following diagnosis Thyroglobulin TG levels in the sera or in fine needle biopsies of thyroid cancer patients are routinely quantified using various agency approved e g FDA immunoassays for diagnostic and p ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Novel Manufacturing Processes for Tissue Engineered Vascular Grafts

    SBC: HUMACYTE, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant This Phase IIB SBIR application is responsive to NHLBI RFA HL andquot NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart Lung Blood and Sleep Disorders and Diseases R andquot This RFA solicits work on andquot basic applied and clinical research on all product and service development related to the ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health

    SBC: Innovation Research And Training, Inc.            Topic: NICHD

    Adolescents with Fetal Alcohol Spectrum Disorder FASD are at risk for substance use and abuse Given the dearth of interventions designed specifically for adolescents with FASD there exists a need for evidence based preventive intervention programs for this population Thus the goal of the proposed Phase II application is to complete the product development and evaluate the effectiveness of t ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Metal Matrix Composite Feedstock for Advanced Fiber Placement Process


    The proposed research pursues a path for reducing structural weight, increasing structural performance, and reducing fabrication cost while also minimizing maintainability. The approach, which is a based on selective reinforcement, is a change in the basic design philosophy and will result in the development of a hybrid material form. The selective reinforcement approach allows the structural de ...

    SBIR Phase I 2013 National Aeronautics and Space Administration
  6. A Real-Time Fault Management Software System for Distributed Environments


    DyMA-FM (Dynamic Multivariate Assessment for Fault Management) is a software architecture for real-time fault management. Designed to run in a distributed environment, DyMA-FM enables model-based reasoning and predictive modeling for FM applications. With the appropriate hardware, DyMA-FM can respond to signals at the device level while still placing each signals in context with the larger system ...

    SBIR Phase I 2013 National Aeronautics and Space Administration
  7. Porous Membrane Electrode for Quantitative Detection of Toxins

    SBC: Mercury Science Inc.            Topic: 816N

    In Phase I, a novel porous electrode was designed to demonstrate a rapid, simple assay for the detection of domoic acid in marine samples. During Phase II, methods to manufacture porous electrodes will be improved to enable high volume production of low-cost biosensors that can be connected to a potentiostat. These biosensors will be incorporated into a portable test kit for the quantitation of do ...

    SBIR Phase II 2013 Department of CommerceNational Oceanic and Atmospheric Administration

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