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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. IGF OT IGF HIGH CONTENT SCREENING FOR HUMAN PRIMARY PANCREATIC CELL TYPE SPECIFIC TOXICANTS

    SBC: ZEN-BIO, INC.            Topic: NIDA

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. CHEMOENZYMATIC SYNTHESIS OF HEPARAN SULFATE OLIGOSACCHARIDES

    SBC: Glycan Therapeutics LLC            Topic: NCI

    The goal of this contract is to synthesize a heparan sulfate HS library consisting of structurally homogeneous oligosaccharides in response to an SBIR contract call from NCl Chemically Defined Glycan Libraries The Contractor specializes in the synthesis of structurally diverse HS oligosaccharides The Contractor has built an innovative chemoenzymatic method for Glycan synthesis Polymeri ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. IGF OT IGF Fluorescent Nanodiamonds for In Vitro and In Vivo Biological Imaging SBIR Topic Phase II

    SBC: Adamas Nanotechnologies, Inc.            Topic: NHLBI

    Not Available

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. IGF OT IGF ARISE AN ONLINE RELAPSE PREVENTION TOOL FOR SUBSTANCE ABUSERS N DA POP SEPTEMBER SEPTEMBER SUPPLEMENTAL W IN SCOPE

    SBC: 3-C Institute for Social Development, Inc.            Topic: NIDA

    Not Available

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Contraceptive testing for semen availability in male monkeys

    SBC: Eppin Pharma Inc            Topic: NICHD

    DESCRIPTION provided by applicant The global contraceptives market was valued at $ billion in and is expected to grow at a CAGR of from to to reach an estimated value of $ billion in An important high impact driver of this market is the prevalence of unintended pregnancies In the US there are million unintended pregnancies annually through inconsistent or ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. New Class of Bright, Sharp, Tunable Red/Far-Red Fluorophores for Flow Cytometry

    SBC: Nirvana Sciences, Inc.            Topic: NIBIB

    DESCRIPTION provided by applicant Polychromatic flow cytometry FC is one of the most powerful analytical techniques used in immunology basic research and clinical medicine In basic research FC is a primary tool for understanding disease development at the cellular and subcellular levels In the rapidly developing field of immunotherapy FC is an indispensable tool for monitoring the effec ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Implantation of Bioengineered Intrinsically Innervated Internal Anal Sphincter (BioSphincter) to Treat Fecal Incontinence

    SBC: CELLF-BIO, LLC            Topic: 300

    DESCRIPTION provided by applicant We propose to bring to market a novel regenerative medicine based therapy for fecal incontinence FI FI is the recurrent uncontrolled passage of fecal material The Internal Anal Sphincter IAS is responsible for maintaining anorectal continence Function of the IAS is dependent upon the neuromuscular integrity of both the smooth muscle and the intrinsic en ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Delivery of peptides for inducing voiding associated with neurological retention

    SBC: Dignify Therapeutics LLC            Topic: 102

    DESCRIPTION provided by applicant Neurological conditions such as multiple sclerosis Parkinsonandapos s disease dementia spina bifida diabetes stroke and spinal cord injury SCI can result in loss of voluntary control over bladder and bowel function often producing both incontinence and retention of urine and stools in the same patient This has a profound impact on the mental and phy ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Development of Small Molecules that Enhance the Delivery and the Pharmacological Effects of Oligonucleotides

    SBC: Initos Pharmaceuticals LLC            Topic: 999

    DESCRIPTION provided by applicant Antisense and siRNA oligonucleotides offer the promise of highly precise manipulation of genes involved in disease pathogenesis However despite the investment of enormous resources that promise has been fulfilled to only a limited degree A key impediment to oligonucleotide based therapeutics is the difficulty in delivering these large highly polar molecule ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Unicondylar Resurfacing in an Ovine Osteoarthritis Disease Model

    SBC: Cytex Therapeutics, Inc.            Topic: NIAMS

    DESCRIPTION provided by applicant The treatment of large cartilage lesions is a difficult clinical problem for which there are few good solutions Left untreated these lesions tend to degenerate to chronic pain and osteoarthritis OA ultimately requiring a total joint replacement For patients suffering from knee OA and in particular unicompartmental OA unicondylar knee arthroplasty UK ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health

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