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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Topic 341: Open Scalable Software Infrastructure for Metabolomics Data

    SBC: Kitware, Inc.            Topic: NCI

    Metabolomics research has great potential, and researchers are rapidly producing new techniques for analyzing the large quantities of measurement data in order to utilize metabolomic data more effectively, including promising techniques for data integration across multiple modalities of data from mass spectrometry (MS) and nuclear magnetic resonance (NMR). However, this confluence of data growth a ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Satellite Ground Station Network for Real-Time Space Weather Data

    SBC: USML L.L.C.            Topic: 843W

    The goal of this Phase II effort is to carry out a series of tasks with the purpose of developing a ground station network that can provide less than 15 minute latency in acquiring data from NOAA space weather assets. These tasks include:  Finalize a set of specifications for ground stations so they can be used to determine the suitability of existing ground stations for the different missions ...

    SBIR Phase II 2017 Department of Commerce
  3. Web Software to develop an RDoC Compatible Adaptive Diagnostic Nosology the SID

    SBC: Health Outcomes Inc            Topic: 102

    n psychiatry clinical judgment has been the predominant method of diagnosis The `gold standard for clinical research is the Structured Clinical Interview for DSM SCID The SCID promotes reliability but its validity is questionable There is growing recognition that biomarkers can be used to identify more homogeneous patient populations but there is substantial phenotypic discordance f ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. The Impact Integrated Data System for Quality and Outcomes Tracking of Prevention Programs

    SBC: 3-C Institute for Social Development, Inc.            Topic: 104

    Abstract There has been substantial progress in developing evidence based prevention programs EBPPs for preventing risky behaviors and promoting positive mental health outcomes for youth Unfortunately EBPP adoption quality implementation long term sustainability and scalability in real world service settings continues to lag far behind jeopardizing the ability to achieve the intended broad ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Functional Tissue Engineering for Cartilage Repair

    SBC: Cytex Therapeutics, Inc.            Topic: NIA

    Abstract It is estimated that only about of young patients suffering from!activity limiting hip osteoarthritis OA choose to undergo traditional hip replacement surgery This low percentage is attributed to the shortened projected lifetime of hip implants for active patients and the subsequent need for revision surgeries that are plagued with higher complication rates and overall decreased ef ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. TARGETED AC RADIOPHARMACEUTICAL FOR METASTATIC UVEAL MELANOMA

    SBC: MODULATION THERAPEUTICS, INC.            Topic: NCI

    Melanocortin receptor MC R is highly expressed on uveal and cutaneous melanoma cells and not on any tissues that are of concern for causing toxicity We developed a proprietary ligand MC RL that binds to melanoma cells with high affinity and specificity Our recently completed SBIR Phase I contract results show no overt toxicity at dosages of Ac DOTA Ahx MC RL that produce outstanding ef ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. VALIDATION OF SHADE A MOBILE TECHNOLOGY FOR MONITORING OF ULTRAVIOLET EXPOSURE

    SBC: YOUV LABS            Topic: NCI

    Shade helps people manage their UV exposure it is a ultraviolet UV monitor with unprecidented accuracyconnected to a mobile application Although it is one of the clearest and most controllable causes of cancer UV exposure can be difficult to estimate due to the importance of combining many rapidly changing factors including intensity shade and use of protective cloting and sunscreen To val ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. High Temperature High Resolution in-situ Differential Pressure Sensor

    SBC: Innoveering, LLC            Topic: NA

    Chemical manufacturers require high accuracy/high sensitivity pressure sensors to efficiently monitor the various manufacturing systems and processes in the chemical plant, to ensure any changes proceed in a safe and reliable manner, adhering to expected standards and practices. NIST also has a need for highly accurate pressure measurements, especially determining the thermo-physical properties of ...

    SBIR Phase II 2017 Department of CommerceNational Institute of Standards and Technology
  9. New Class of Bright Sharp Tunable Near Infrared Fluorophores for Flow Cytometry

    SBC: Nirvana Sciences, Inc.            Topic: R

    DESCRIPTION provided by applicant Polychromatic flow cytometry FC is one of the most powerful analytical techniques routinely used by both basic research and clinical diagnostics laboratories for the immunological categorization of cells Dyes used for FC typically exhibit broad fluorescent emission bands with full width at half maximum fwhm values of nm This limits the maximum numbe ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Development and validation of therapy for mucopolysaccharidosis III

    SBC: Phoenix Nest Inc.            Topic: 105

    DESCRIPTION provided by applicant Sanfilippo syndrome mucopolysaccharidosis type III MPS III is a devastating neurodegenerative lysosomal storage disorder of childhood for which there is presently no cure or effective treatment available The fundamental cause of MPS III is an inherited mutation in one of the enzymes required to catabolize heparan sulfate HS a glycosaminoglycan which pla ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health

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