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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. HUMAN MONOCOLONAL ANTIBODIES FOR CNS REMYELINATION

    SBC: Acorda Therapeutics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The primary goal of the current research will be to select the best recombinant form of one of two naturally occurring human igM antibodies demonstrated to stimulate remyelination to further develop for clinical testing in inflammatory demyelinating disease, such as MS. These antibodies, designated sHIgM22 and sHIgM46, were isolated by the Rodriquez laboratory ...

    STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  2. HUMAN MONOCOLONAL ANTIBODIES FOR CNS REMYELINATION

    SBC: Acorda Therapeutics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The primary goal of the current research will be to select the best recombinant form of one of two naturally occurring human igM antibodies demonstrated to stimulate remyelination to further develop for clinical testing in inflammatory demyelinating disease, such as MS. These antibodies, designated sHIgM22 and sHIgM46, were isolated by the Rodriquez laboratory ...

    STTR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  3. INNOVATIVE TECHNOLOGY FOR GENE EXPRESSION STUDIES

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    Alderon Biosciences proposes to develop a new electrochemical method for detection of specific nucleic acid sequences without enzymatic, fluorescent or radioactive labels and to show the feasibility of applying this method in an electrochemical plate (E-Plate) format to studies of gene expression in cancer. The E-Plate, an electrical analog of a traditional microplate and reader, will be developed ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  4. REDUCING HYPERACTIVITY WITH A FEEDBACK ACTIGRAPH

    SBC: AMBULATORY MONITORING, INC.            Topic: N/A

    This application addresses the need for an alternative to pharmacological treatment of children diagnosed with ADHD (and other conditions that may present motoric excess). Technological enhancements to the Phase I Feedback Actigraph, now referred to as BuzzBee¿, will allow multiple activity recorders (belt-worn by ADHD diagnosed children) equipped with vibrotactile, auditory, and visual feedback ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  5. REDUCING HYPERACTIVITY WITH A FEEDBACK ACTIGRAPH

    SBC: AMBULATORY MONITORING, INC.            Topic: N/A

    This application addresses the need for an alternative to pharmacological treatment of children diagnosed with ADHD (and other conditions that may present motoric excess). Technological enhancements to the Phase I Feedback Actigraph, now referred to as BuzzBee¿, will allow multiple activity recorders (belt-worn by ADHD diagnosed children) equipped with vibrotactile, auditory, and visual feedback ...

    SBIR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  6. A MATERNALLY LINKED DATA SET WITH ANALYTIC AIDS

    SBC: ANALYTICAL SCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to improve the health of women and infants by enabling crucial research in areas such as SIDS, insufficient or excessive maternal weight gain, short interpregnancy intervals, and birth defects. Advances in understanding the causes and prevention of these and other problems require studies that include more than one pregnancy/birth fo ...

    SBIR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  7. A MATERNALLY LINKED DATA SET WITH ANALYTIC AIDS

    SBC: ANALYTICAL SCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to improve the health of women and infants by enabling crucial research in areas such as SIDS, insufficient or excessive maternal weight gain, short interpregnancy intervals, and birth defects. Advances in understanding the causes and prevention of these and other problems require studies that include more than one pregnancy/birth fo ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  8. RENAL INJURY PREVENTION BY SF/HGF-LIKE SMALL MOLECULES

    SBC: Angion Biomedica Corp.            Topic: N/A

    DESCRIPTION (provided by applicant): Recent studies support the concept that treatment with scatter factor/hepatocyte growth factor can prevent renal dysfunction in mouse models of renal failure. SF/HGF has multiple actions such as proliferative, pro-fibrinolytic and anti-apoptotic activities that may contribute to this protective function. Recently we have discovered small peptide sequences usin ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  9. ANTI-ANGIOGENIC & ANTI-TUMOR DRUG FOR HUMAN GLIOMA

    SBC: Angion Biomedica Corp.            Topic: N/A

    Numerous novel approaches to cancer therapy are currently being examined including gene therapy, immunotherapy and combinations of traditional and novel therapies. By targeting multiple events in the proliferation and spread of cancer cells the effectiveness of treatments may be improved and resistance to therapy avoided. Since SF/HGF may promote tumor growth through multiple actions both on cance ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  10. SF/HGF GENE TRANSFER FOR PERIPHERAL ISCHEMIA

    SBC: Angion Biomedica Corp.            Topic: N/A

    Cardiovascular disease is the leading cause of morbidity and mortality in the US, afflicting over 58 million Americans. Angiogenic factors can increase vascularization and improve perfusion in ischemia. Scatter factor/hepatocyte growth factor (SF/HGF) may be superior to other angiogenic factors because of multiple actions on components of the angiogenic cascade and anti-apoptotic properties. Our P ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
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