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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Integration of Lumbar Extensor Muscle Strengthening with Ergonomic Seating

    SBC: ABOVE FITNESS PRODUCTS, LTD            Topic: N/A

    DESCRIPTION (provided by applicant): This grant proposes an innovative approach to prevent low back pain and injury associated with prolonged seating. Specifically, we propose to integrate lumbar extensor muscle strengthening with ergonomic task seating. By doing so, we will provide the public with a means to address two primary causes of low back pain and injury: 1) poor or prolonged seating po ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Demand Driven Healthcare Scheduling using Flexible Shifts and Monte Carlo Simulat

    SBC: Acme Express, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The shortage of healthcare workers is accelerating. An longer-living, ageing population is demanding more medical service while healthcare worker retirements and high turnover is decreasing the worker pool. Shortages ca n be reduced or eliminated by scheduling only the number of staff needed to meet the hour-by-hour demand for medical service and using flexible ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  3. Nanoliter Lab-on-a-Chip for Rapid Parallel Immunoassays

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): The great need for more efficient and effective oncologic drug development has driven the discovery and integration of biomarkers into all phases of clinical research. Further still, biomarkers are entering the clinical arena as early means of determining which patients are likely benefiting from a particular drug. One field of targeted therapy that has relied ...

    SBIR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Multiplexing Cancer Sample Preparation: Indirect Immunomagnetic Enrichment

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): Biomarkers of clinical activity are critical for targeted anti-cancer therapy development and are becoming important for the care of individual patients. In a prototypical tyrosine kinase pathway, governed by the epider mal growth factor receptor (EGFR), functional activity of the pathway is assessed by the phosphorylation status of EGFR and downstream signalin ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  5. Improved Silicon Drift Detector Coincidence Rejection for Digital Pulse Processors

    SBC: 4pi Analysis, Inc.            Topic: N/A

    The recent emergence of the Silicon Drift detector (SDD), for use in Energy Dispersive x-ray Spectroscopy (EDS), has made possible x-ray event streams with input count rates in the range of 1-10 Mcps. Modern digital pulse processors are therefore required to run at fast time constants to achieve reasonable throughput; however, this causes significant coincidence artifacts to appear in the spectrum ...

    SBIR Phase I 2008 Department of CommerceNational Institute of Standards and Technology
  6. Development of a high-throughput screen for inhibitors of water permeability thro

    SBC: AEROMICS, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Cerebral edema (and its counterpart in the spinal cord) is a major contributor to the damage caused by stroke, traumatic brain injury, traumatic spinal-cord injury, and bacterial meningitis. Stroke alone is the third le ading cause of death in the USA and the leading cause of disability. Unfortunately, only a few treatment options are available for cerebral and ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  7. Localized Growth Factor Therapy for Surgical Hernia Repair

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Over 700,000 surgical hernia repairs are performed each year in the United States and despite recent advances, a significant rate of recurrence persists. The incorporation of biocompatable mesh to strengthen the abdomi nal fascia has largely replaced high-tension suturing techniques in hernia repair. Currently, the preferred biomaterials include durable synthe ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  8. Antibiotic-binding Peptides for Biofilm Prevention on Ventriculoperitoneal Shunts

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Ventriculoperitoneal (VP) shunts are used to treat pediatric and neonatal hydrocephalus in severe cases, representing approximately 1/3rd of affected infants. Due to the high susceptibility for infection and mechanica l breakdown, the failure rate of VP shunts is around 30-40%. A need therefore exists to improve infection prevention for this procedure, likely ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  9. Tissue-targeted Antibiotics for the Prevention of Surgical Site Infection

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The Centers for Disease Control estimates that as many as 2 million people contract infections in hospitals each year, with as many as 100,000 deaths. Approximately 1/4 of hospital related infections (~500,000) are surg ical site infections. For each single patient, surgical site infections have been reported to require a median 6.5 additional days of hospital ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  10. Self Assembling High Affinity Peptides for Point of Care Drug-Device Combinations

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Infection surrounding metal implants is a common and sometimes devastating cause of implant failure in a number of fields including oral, craniomaxillofacial (CMF), orthopedic, and cardiovascular surgery. These infectio ns, which arise from the establishment of biofilms on device surfaces, not only necessitate new surgeries but in themselves present a significa ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
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