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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Nanodroplet PCR Lab-Chip for Clinical Pathogen Detection

    SBC: ADVANCED LIQUID LOGIC            Topic: NIAID

    DESCRIPTION (provided by applicant): It is estimated that 2 million health-care associated infections are acquired each year by hospitalized patients resulting in 90,000 deaths and about 4.5 billion in excess health care costs. A large and growing percentage of these infections can be attributed to Staphylococcus aureus and, in particular, to methicillin-resistant S. aureus (MRSA). Rapid PCR-base ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Not Available

    SBC: ADVANCED LIQUID LOGIC            Topic: NHLBI

    Not Available

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Improved Joints Based on 3D Fiber Architecture Preforms

    SBC: 3TEX, Inc.            Topic: 20a

    Wind blades are complex constructions of composite materials. As with all composite structures, forming joints between the various elements has long been problematic, since composites cannot easily be bolted, fastened, or welded together. Current manufacturing methods result in thick adhesive layers that have varying dimensions and which are the most common failure area in wind blades during opera ...

    SBIR Phase II 2010 Department of Energy
  4. Localized Growth Factor Therapy for Surgical Hernia Repair

    SBC: AFFINERGY, LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): Over 700,000 surgical hernia repairs are performed each year in the United States and despite recent advances, a significant rate of recurrence persists. The incorporation of biocompatible mesh to strengthen the abdominal fascia has largely replaced high-tension suturing techniques in hernia repair. Currently, the preferred biomaterials include durable syntheti ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  5. Development of an adipose-derived stem cell isolation matrix

    SBC: AFFINERGY, LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): Mesenchymal stem cells (MSCs) are an adult stem cell population, typically isolated from bone marrow aspirates, and are capable of self-renewal, expansion in culture, and differentiation into adipocytes, chondrocytes, and osteoblasts. These cells are being explored for use in tissue engineering applications, such as spinal fusions, bone defect repairs, and cart ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Recombinant expression of a biomaterial-targeting BMP-2 containing a peptide tag

    SBC: AFFINERGY, LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): The emergence of biological therapeutics, including cells, peptides, and proteins, has allowed medical science to address a number of unmet clinical needs. Often these agents are extremely potent, specifically activating endogenous signaling cascades to promote well-characterized biochemical and physiological responses. For example, bone morphogenetic protein-2 ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Next-Generation Detector and Imager Development

    SBC: American Semiconductor, Inc.            Topic: 44d

    Improvements in silicon-on-insulator (SOI) technology have resulted in development of monolithic chip designs for radiation image sensors and particle detectors by facilitating the use of the handle silicon layer for the detectors and the SOI layer for the readout circuits. Unfortunately, even the most advanced SOI-based imagers are still limited in effectiveness due to threshold (Vt) shifts when ...

    SBIR Phase I 2010 Department of Energy
  8. Platelet-based Nanoparticle Therapy for Prostate Cancer

    SBC: ANDROBIOSYS, INC.            Topic: NCI

    The goal of this Phase II proposal is to develop directed energy transfer methods for imaging, tissue ablation and release of therapeutic modalities targeted to the vasculature of prostate cancer. The platform technology is a freeze-dried human platelet (Stasix particles) that contains super paramagnetic iron oxide (SPIO) nanoparticles. The Phase I program showed that SPIO-Stasix particles selecti ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  9. A Pilot Clinical Study in Acute STEMI

    SBC: Angion Biomedica Corp.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Percutaneous coronary intervention (PCI) has become the mainstay for treatment of ST-segment elevation myocardial infarction (STEMI). Whereas early recanalization undoubtedly salvages myocardial tissue, reperfusion following prolonged ischemia can also exacerbate injury. Infarct size needs to be limited, and the conditions favoring adaptive ventricular healing ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Anti-Fibrotic Therapy for Scleroderma/SSc

    SBC: Angion Biomedica Corp.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Scleroderma (also known as systemic sclerosis-SSc) is an autoimmune disorder characterized primarily by progressive dermal and vascular fibrosis. Other organs are affected too, including lung, heart, esophagus, intestine, and kidney. Many patients who suffer from scleroderma/SSc also have a loss of pulmonary function. Scleroderma/SSc affects approximately 400,0 ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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