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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Radioprotection by use of Topical Lithium Formulations

    SBC: CUMBERLAND PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Roughly 500,000 cancer patients are treated with radiotherapy each year. Acute and late sequelae of radiotherapy have a negative impact upon the quality of life of cancer survivors. These sequelae include proctitis, cystitis, esophageal stricture, cutaneous fibrosis plus others. We propose a novel means of preventing the acute and late radiation injury to norma ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  2. Mannan, A Potential Therapeutic for Asthma

    SBC: CUMBERLAND PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long-term goal of this application is to develop mannan derived from Baker's yeast as asthma therapy. The limitations of currently available immunomodulators are their toxicity at higher doses and the lack of beneficial effect on airway smooth muscle (ASM) remodeling and therefore, new adjunctive therapeutics are needed. Initial findings in the P.I.'s labor ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  3. Functional Tissue Engineering for Cartilage Repair

    SBC: Cytex Therapeutics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Degenerative joint diseases such as osteoarthritis remain the source of significant pain and disability, affecting 20 million adults with an economic burden of over 40 billion per year to the United States. While joint replacement is a well-established procedure, its finite life span makes this treatment unacceptable for younger or more active individuals, of ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  4. Fast Spectral Imaging Device For Tumor Margin Mapping

    SBC: Zenalux Biomedical, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The American Cancer Society estimates that a total of 240,430 new breast cancers were diagnosed in 2007 (178,400 new cases of invasive breast cancer, and 62,030 new cases of in situ breast cancer). Approximately 180,000 of these patients undergo breast conserving surgery (BCS), also called lumpectomy. Multiple recent studies show that a staggering 20-70% of the ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  5. Development of ADAM10 Prodomain as a Therapeutic Agent

    SBC: BIOZYME, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Recent cancer therapies have focused on using biologics to target specific signal transduction pathways implicated in the tumor development or progression. For example, recombinant fusion proteins consisting of the extracellular domain of the immunoregluatory proteins and the constant (Fc) domain of immunoglobulin (IgG) represent a growing class of protein ther ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  6. A Universal Brain Atlas for Implanting and Managing Deep Brain Stimulators

    SBC: Neurotargeting, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Neurotargeting, LLC proposes to develop the technical support infrastructure as well as clinical tools for a commercial software product that will provide a global service for the medical community involved in deep brain stimulator (DBS) therapy. Specifically, this Phase I study will explore the use of a physiological atlas database that can interface with a nu ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  7. Interfacing of Research Modalities in Developmental Cognitive Neuroscience

    SBC: Perception Research Systems Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Biobehavioral research in a range of basic and translational disciplines (particularly cognitive neuroscience, neuropsychology and experimental psychology) increasingly involves the integration of multiple devices for the collection of data, such as EEG, fMRI, eye-tracking and physiological measurements (galvanic skin response, EKG). Current state-of-the-art ex ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  8. The identification of novel negative allosteric modulators of the nicotinic recep

    SBC: Promiliad Biopharma Incorporated            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this Phase I STTR project is to identify novel negative allosteric modulators of the nicotinic acetylcholine receptor. This project seeks to partner the drug discovery technology of the Promiliad Biopharma with the expertise of Professor Dennis McKay to identify novel and subtype selective negative allosteric modulators of the nicotinic acetylcholin ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  9. Prevention Buffet: An Internet Prevention Resource for Middle Schools

    SBC: TANGLEWOOD RESEARCH INC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this STTR Phase I proposal is to develop a searchable Internet database of prevention lessons called Prevention Buffet. The database will allow middle school teachers to customize prevention efforts in their classrooms to the needs of their students, while providing them with guidance in selecting and implementing prevention lessons. Lessons will be ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  10. NF-kB Inhibition of Lung Ischemia Repurfusion Injury

    SBC: THERALOGICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Ischemia-reperfusion injury (IRI) is a major problem in many clinical scenarios, including myocardial infarction and stroke. IRI is also a major problem in organ transplantation, because IRI is the major cause of primary graft failure and organ dysfunction after transplant. Increasingly, graft injury due to IRI at the time of implantation is recognized as a maj ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
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