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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Clinical-scale Production of Osteoprogenitor Cells

    SBC: Aastrom Biosciences, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Due to morbidity and limited amounts of material, alternatives to autologous grafts for bone repair are desirable. Cells within the bone marrow are known to possess bone regenerative capacity, but they are limited in number. Increasing these osteoprogenitor cell populations through the use of ex vivo expansion technologies and combining these cells with a matri ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Clinical Human Cell Production System for Broad Use

    SBC: Aastrom Biosciences, Inc.            Topic: N/A

    The therapeutic potential of patient-specific cultured cells continues to rapidly grow for a range of medical needs, such as regenerative repair of damaged tissue, cancer, and infectious diseases. As a result, the motivation to commercialize patient-specific "cell products" is increasing rapidly as well. A large unmet need exists for the development of reliable clinical and commercial ceil manufac ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  3. EFFICIENT AND EFFECTIVE MOBILE DATA CAPTURE IN AN ACRIN CLIN TRIAL ENVIRON

    SBC: ADVANCED DIGITAL SYSTEMS, INC.            Topic: N/A

    N/A

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Nanodroplet PCR Lab-Chip for Clinical Pathogen Detection

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): Rapid and accurate detection and identification of pathogens is crucial for the effective management and treatment of infectious disease. While molecular diagnostic techniques including PCR are a promising approach for rapid and sensitive detection of pathogens, they suffer from a number of technical drawbacks which have slowed their acceptance in the clinic. ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. Transdermal Patch for Pulsatile Nicotine Delivery

    SBC: ADVANCED SENSOR TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Current nicotine delivery patches rely on the passive diffusion of nicotine through the skin and into the fluid that surrounds the cells beneath the skin (interstitial fluid). From there, the nicotine diffuses into the capillary network, enters the blood stream, and is delivered to the brain. The nicotine is contained in a textile fiber material within the p ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. A Novel Needle-based X-ray System

    SBC: ADVANCED X-RAY TECHNOLOGY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The main objective of this project is to design, fabricate and experimentally research the application of capillary x-ray optics as a means of elevating the dose rate of the radiation produced by a needle-based x-ray system. The goal is to reach the dose rate of 10 Gy/hour at a distance 5 mm from the pseudo-target. The other objective is to apply capillary ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Discovery of Peptide-based Bone Morphogenic Protein Mimetics

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In this proposal, we present a novel approach for the identification and immobilization of a BMP mimetic. We plan to use phage display technology to identify peptides that mimic BMP-like signaling of the BMP receptors. These peptides will be linked to a previously identified high-affinity, collagen-binding peptide. The resulting hybrid molecule will allow contr ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Improved Orthopedic Implant Surface Coatings

    SBC: AFFINERGY, LLC            Topic: N/A

    Endosseous metallic implants are common alloplastic devices used in medicine and dentistry. The orthopedic and dental marketplace continues to grow and indications for implants are expanding. There is a perceived need to improve both the successful healing (osseointegration) and the long term outcome of implants by control of interfacial reactivity during healing and remodeling. The growth of know ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Electrochemical RT activity assay for measuring HIV load

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): In this Phase I SBIR project Alderon Biosciences Inc. (ABI) proposes to demonstrate the feasibility of using electrochemical reverse transcriptase (eRT) assays for determinations of HIV viral load in clinical samples. Success will set the stage for Phase II development, FDA approval, and production of commercial kits using this advanced technology. The long-r ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Electrochemical Quantification of HCV RNA

    SBC: ALDERON BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The National Institutes of Allergy and Infectious Disease have called for better tools for the detection and diagnosis of emerging and re-emerging infectious diseases. To meet this need, Alderon Biosciences Inc. (ABI) proposes to develop innovative, low-cost tests with sensitivity adequate for determining HCV viral load. Reliable and affordable HCV viral load t ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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