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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Nanoliter Lab-on-a-chip for Protein Crystallization
SBC: ADVANCED LIQUID LOGIC Topic: N/ADESCRIPTION (provided by applicant): The human genome contains at least 30,000 unique open reading frames that may yield >100,000 polypeptide products. These products assemble into more than a million biologically relevant structures or proteins of interest per organism. Crystallization and X-ray diffraction of these proteins is routinely performed to determine their 3D structure which needs to be ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
Nanoliter Lab-on-a-Chip for Blood Diagnostics
SBC: ADVANCED LIQUID LOGIC Topic: N/ADESCRIPTION (provided by applicant): Latrogenic blood loss or "bleeding into the laboratory" is an important reason for administration of small volume transfusions in very low birth weight premature 6infants. A direct correlation was found between the volume of blood drawn for diagnostics and subsequent volume transfused. In neonatal infants, there may not be enough collected blood sample to perfo ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
Improved Orthopedic Implant Surface Coatings
SBC: AFFINERGY, LLC Topic: N/ADESCRIPTION (provided by applicant): Many contemporary medical and dental therapies include the replacement or repair of tissues using materials such as metal. Currently there are at least 150,000 hip replacements, 300,000 knee replacements, and 500,000 dental implant procedures performed in the US each year (Kurtz, Mowat et al. 2005). These numbers are expected to increase as the baby boom gen ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
Clinical Development a Therapeutic Agent for COPD
SBC: BIOMARCK PHARMACEUTICALS, LTD Topic: N/AHypersecretion of mucus into the respiratory airways is a major contributing factor in several lung diseases, including chronic pulmonary disease (COPD), asthma, cystic fibrosis, and bronchiectasis. Despite the obvious medical importance, there presently are no effective therapies to control excess mucus secretion in these diseases, and very few potential therapeutic targets. We discovered that a ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
Ophthalmic Optical Coherence Tomography
SBC: BIOPTIGEN, INC. Topic: N/ADESCRIPTION (provided by applicant): This Phase II Small Business Innovative Research application proposes to dramatically expand the commercial availability of optical coherence tomography (OCT) technology for pre-clinical human and animal research applications by commercializing Fourier-domain OCT (FD-OCT) technology and developing robust interfaces for retinal OCT imaging in a wide variety of s ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
IDENTIFICATION OF NEW ACETYL-COA CARBOXYLASE INHIBITORS
SBC: CROPSOLUTION, INC. Topic: N/ADESCRIPTION (provided by applicant): Acetyl-CoA carboxylase (ACC) catalyzes the first step in fatty acid biosynthesis and its product, malonyl-CoA, inhibits fatty acid oxidation. These functions make ACC a prime target for the development of therapeutics to treat obesity and type 2 diabetes. Knockout studies in mice, and animal studies with ACC inhibitors, have validated this approach. The most po ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
Demographic Tool & Database for Households Forecasting
SBC: HOUSEHOLD AND CONSUMPTION FORECASTING, I Topic: N/ADESCRIPTION (provided by applicant): The goal of this SBIR Phase II project is to continue our Phase I work to develop the ProFamy package, which includes commercialized professional software, an input database, and output archive. The software and input database are for household and consumption forecasting at national, state and small area levels. The output archive contains the outcome of house ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
Construction of a Force Probe for Characterization of Microscale Features
SBC: INSITUTEC, INC. Topic: N/AThe Phase 2 objective is to provide NIST with a modular gauge head unit equipped with InsituTec's standing wave probe technology. The complete gauge head unit will be retrofitted to the NIST M48 which is one of the most precise measuring machines in the world. This unit will enable NIST to achieve the agency's program goal in dimensional metrology which is to provide microscale measurement capacit ...
SBIR Phase II 2006 Department of CommerceNational Institute of Standards and Technology -
DEVELOPMENT OF EPITHELIAL SODIUM CHANNEL BLOCKERS FOR CF
SBC: Parion Sciences, Inc. Topic: N/ADESCRIPTION (provided by applicant): Our preliminary data support the hypothesis that 552-02 is a potent, selective inhibitor of epithelial sodium channels that is effective in enhancing mucociliary clearance and is well tolerated when administered as a single dose by inhalation aerosol in normal healthy adult volunteers. The general approach to be followed in the continued evaluation of 552-02 du ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health -
Low Cost Production of Recombinant Proteins
SBC: PhaseBio Pharmaceuticals Inc Topic: N/ADESCRIPTION (provided by applicant): There are an increasing number of protein drugs in the pipeline, whose cost of production is very high compared to synthetic, small molecule drugs. Further, a number of protein drugs are coming off patent in the next few years, which will create an opening for a market for generic version of these drugs, if they can be produced at significantly lower cost and d ...
SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health