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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Unicondylar Resurfacing in an Ovine Osteoarthritis Disease Model
SBC: Cytex Therapeutics, Inc. Topic: NIAMSAbstractThe treatment of large cartilage lesions is a difficult clinical problem for which there are few good solutionsLeft untreatedthese lesions tend to degenerate to chronic pain and osteoarthritisOAultimately requiring a total joint replacementFor patients suffering from knee OAandin particularunicompartmental OAunicondylar knee arthroplastyUKAis an available first line treatment option that p ...
STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
PLATFORM FOR NEUROCOGNITIVE EVALUATION AND MONITORING
SBC: ENFORMIA INC. Topic: NCICurrent standardized neuropsychological tests are based on decades old paper and pencil methods They lack reliability sensitivity specificity repeatability and require trained neuropsychologists to administer them Their administration in clinical and research settings result in high cost complexity and inconsistent results There is a need and a commercial opportunity for an extensible co ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
An RNA targeted platform for anti flavivirus drug discovery
SBC: Ribometrix LLC Topic: NIAIDSUMMARY Emerging and re emerging mosquito borne flaviviruses cause widespread mortality morbidity and economic burden Options for prevention and treatment of mosquito borne flaviviruses are limited Flavivirus vaccines face unique development challenges no antiviral therapies are available and the mosquito vectors have proven difficult to eradicate Despite vaccines against Yellow Fever and J ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Development of user-friendly fluorescence based assays for marine toxins
SBC: SEATOX RESEARCH INC Topic: 113ABSTRACTHarmful algal bloomsHABsare becoming frequent occurrences off the coasts of the United Stateswith specific instances in the coastal waters of the west coastthe Gulf of Mexicoand the Pacific OceanHistoricallyHABs have been associated with fish kills and marine mammal mortalitieshowevertheir effects on human health and economic loss due to HAB contamination of seafood are becoming more preva ...
STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
A Phase I Clinical Trial: Binary Therapy with DM-CHOC-PEN and WBRT in Adults with Cancer Involving the CNS
SBC: DEKK-TEC INC Topic: NCIThe goal of this Phase I clinical trial will be to document safety and potential usefulness ofdemethylcholesteryloxycarbonylpenclomedineDM CHOC PENin combination with de escalating doses of whole brain radiation therapyWBRTas binary therapy in subjects with advanced cancer involving the CNSa Phase I clinical trialDM CHOC PEN is a polychlorinated pyridyl cholesteryloxycarbonatewhich has completed P ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Peptide based tool for the rapid isolation of quiescent monocytes from peripheral blood
SBC: AFFINERGY, LLC Topic: 102SUMMARY ABSTRACT Dendritic cell DC therapy represents a new and promising immunotherapeutic approach for treatment of advanced stage cancers with DC vaccines already approved for use in advanced prostate cancer and more than DC based vaccines in the clinical development pipeline for other cancers In particular the US market for cancer vaccines including DC based vaccines is set to expan ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
IND Enabling Studies of ZB an Orally Bioavailable SERD
SBC: Zenopharm, LLC Topic: 102IND enabling Studies of ZB an Orally Bioavailable SERD Project Summary Most patients with advanced metastatic breast cancer eventually develop resistance to tamoxifen or aromatase inhibitor AI treatment where the recurrent and or progressive disease retains the expression of ER The standard treatment of breast cancer progressing after tamoxifen or AI therapy is fulvestrant which is the onl ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Inexpensive, sensitive and specific, point-of-care diagnostic for bacterial infections in the central nervous system
SBC: CNine Biosolutions Topic: NIAIDThe objective of this Phase I application is to develop and assess a sMAC lateral flow assay diagnostic tool for bacterial meningitisBMDevelopment of rapidhighly sensitive and specific clinical diagnostic for bacterial infections in the central nervous systemCNSsuch as BM and shunt infectionthat are easy to use and cost effectivewould significantly improve healthcare in the US and worldwideWe have ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Novel enzyme inhibitor screening platform using modified designer nucleosomes
SBC: Epicypher, Inc. Topic: 300Project Summary Nucleosomes are the basic units of chromatin comprised of a histone octamer made up of two copies of each of the histone subunits H A H B H and H Changes in chromatin structure and function are mediated through histone post translational modifications PTMs such as methylation and ubiquitination Alterations of specific PTMs are highly associated with human diseases i ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Microfluidic S nitrosothiol Sensor
SBC: CLINICAL SENSORS, INC. Topic: 400PROJECT SUMMARY This Small Business Innovation Research SBIR Phase I project aims to develop an accurate rapid and commercially available microfluidic sensor that measures low molecular weight S nitrosothiols in biological samples S nitrosothiols RSNOs the primary transporters of nitric oxide NO in physiology play a critical role for NOandapos s bioactivity Homeostatic control of low ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health